Levofloxacin
Levofloxacin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Levofloxacin is a brand name. Its generic name is Levofloxacin.
Levofloxacin Introduction
Levofloxacin is an antibiotic that belongs to the family of medications known as quinolones. It is used to treat a variety of bacterial infections including, chest and urinary tract infections. It works by stopping the growth of bacteria.
Uses for Levofloxacin
Levofloxacin is used to treat a variety of bacterial infections, including:
- respiratory tract infections
- urinary tract infections, including prostatitis
- skin and soft tissue infections
- acute bacterial sinusitis
- complicated intra-abdominal infections
- chronic bacterial prostatitis
Mechanism of Action
Levofloxacin works by interfering with bacterial DNA synthesis. It inhibits the action of an enzyme called DNA gyrase, so that the bacteria can no longer reproduce. This stops the bacteria from growing and allows the body’s natural defences to fight the infection.
How Long Does it Take to Work?
Levofloxacin typically starts to work within 48-72 hours, although this can vary depending on the severity and type of infection.
Absorption
Levofloxacin is rapidly and almost completely absorbed from the gastrointestinal tract.
Route of Elimination
Levofloxacin is eliminated largely in the urine, with smaller amounts eliminated in the feces. It is eliminated primarily by the kidneys.
Dosage
The dosage of Levofloxacin will vary depending on the type and severity of the infection being treated. The usual dose for adults is 250-500mg per day, taken once or twice daily. For children, the dose may be lower depending on the child's weight and age.
Administration
Levofloxacin should be taken with plenty of fluids. It should not be taken with alcohol, as this may increase the risk of side effects. It should be taken on an empty stomach, at least one hour before food, or two hours after food.
Side Effects
The most common side effects associated with Levofloxacin include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, insomnia, fatigue, and rash. More serious side effects may include allergic reactions, tendon or joint pain, muscle weakness, seizures, and liver damage.
Toxicity
At therapeutic doses, Levofloxacin is generally well-tolerated. The most serious adverse reaction is liver injury, which can occur at high doses. Other less serious but more commonly reported adverse reactions include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, insomnia, fatigue, and rash.
Precautions
Before using Levofloxacin, talk to your healthcare provider about any allergies, your medical history, and any other medications you may be taking. Tell your healthcare provider if you have ever had any kidney or liver problems, G6PD deficiency, any joint or tendon problems, or any mental health issues including depression or suicidal thoughts. Let your healthcare provider know if you are pregnant or breastfeeding before using Levofloxacin.
Interactions
Levofloxacin can interact with other medications, vitamins, and herbal supplements. Tell your healthcare provider about all other medications you are taking before taking Levofloxacin. Some medications that may interact with Levofloxacin include blood thinners, anti-seizure medications, and certain antibiotics.
Disease Interactions
Levofloxacin should not be used by patients with a known hypersensitivity to quinolone antibiotics. Patients with a history of tendon disorders should also not use Levofloxacin. Patients with any kidney or liver disease should use this medication with caution.
Drug Interactions
Levofloxacin can interact with other medications, vitamins, and herbal supplements. Tell your healthcare provider about all other medications you are taking before taking Levofloxacin. Some medications that may interact with Levofloxacin include blood thinners, anti-seizure medications, and certain antibiotics.
Food Interactions
Levofloxacin should be taken on an empty stomach. Avoid taking it with alcohol, as this may increase the risk of side effects.
Pregnancy Use
Levofloxacin should not be used during pregnancy, as it may cause birth defects. Tell your healthcare provider if you are pregnant before taking Levofloxacin.
Lactation Use
Levofloxacin is not recommended for use in breastfeeding women, as it may pass into breast milk and cause harm to a nursing baby. Tell your healthcare provider if you are breastfeeding before taking Levofloxacin.
Acute Overdose
Symptoms of an acute overdose of Levofloxacin include confusion, tremors, restlessness, nausea, and vomiting. Seek medical attention immediately if you think you have taken too much Levofloxacin.
Contraindication
Levofloxacin should not be used by patients with a known hypersensitivity to quinolones. Patients with a history of tendon disorders should also not use Levofloxacin. Patients with any kidney or liver disease should use this medication with caution.
Use Direction
Levofloxacin should be taken exactly as prescribed by your healthcare provider. Do not take more or less of the medication than prescribed. Take the medication on an empty stomach at least one hour before food, or two hours after food. Take Levofloxacin with plenty of fluids. Do not take with alcohol, as this may increase the risk of side effects. Do not stop taking the medication early, or skip doses, even if you feel better.
Storage Condition
Levofloxacin should be stored at room temperature, away from heat and direct light. Keep the medication in the original container, and keep it tightly closed. Do not store the medication in the bathroom or near a sink. Keep all medication out of sight and reach of children.
Volume of Distribution
Levofloxacin is highly soluble in water and is widely distributed throughout the body. It has a volume of distribution of 0.77-1.5 L/kg.
Half Life
The half-life of Levofloxacin is about 8 hours, but may be longer in patients with reduced renal function.
Clearance
Renal clearance of Levofloxacin is approximately 25 mL/min. Liver metabolism is not significant.
Here you find in details version of Levofloxacin
Some Frequently Asked Questions About Levofloxacin
s.What is Levofloxacin?
Levofloxacin is an antibiotic medication used to treat a wide variety of bacterial infections. It belongs to a class of antibiotics called fluoroquinolones and works by stopping the growth of bacteria.
What are the uses of Levofloxacin?
Levofloxacin is used to treat a number of bacterial infections, including bronchitis, pneumonia, sinus infections, skin infections, urinary tract infections, and some sexually transmitted diseases.
Is Levofloxacin an antibiotic?
Yes, Levofloxacin is an antibiotic medication used to treat bacterial infections.
What is the usual adult dose of Levofloxacin?
The usual adult dose of Levofloxacin is 250 to 750 mg daily, depending on the type of infection being treated.
Is Levofloxacin a form of penicillin?
No, Levofloxacin is not a form of penicillin; it belongs to a class of antibiotics called fluoroquinolones.
What is Levofloxacin used for?
Levofloxacin is used to treat a number of bacterial infections, including bronchitis, pneumonia, sinus infections, skin infections, urinary tract infections, and some sexually transmitted diseases.
Should I take Levofloxacin with food?
Levofloxacin can be taken with or without food. However, for best absorption, it should be taken with a full glass of water.
How long do I need to take Levofloxacin?
It is important to take Levofloxacin until you have completed the prescribed course of treatment, even if you start to feel better. Generally, Levofloxacin is taken for a period of 5 to 14 days.
Why is Levofloxacin prescribed?
Levofloxacin is prescribed for a number of bacterial infections, including bronchitis, pneumonia, sinus infections, skin infections, urinary tract infections, and some sexually transmitted diseases.
When should I take Levofloxacin?
Levofloxacin should be taken at least 1 hour before or 2 hours after meals, or as directed by your doctor.
Can I drink alcohol while taking Levofloxacin?
No, it is not recommended to drink alcohol while taking Levofloxacin as it may increase the risk of side effects. It is best to check with your doctor first before drinking alcohol.
Are there any side effects associated with Levofloxacin?
Common side effects associated with Levofloxacin include nausea, diarrhea, dizziness, headache, and rashes. More serious side effects include liver damage, tendon rupture, and changes in heart rhythm.
Do I need to avoid sunlight while taking Levofloxacin?
Yes, it is important to avoid direct sunlight and sunlamps while taking Levofloxacin, as it can increase the risk of sunburn. If you must go out in the sun, wear protective clothing and use sunblock.
What should I do if I miss a dose of Levofloxacin?
If you miss a dose of Levofloxacin, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
How long does it take for Levofloxacin to work?
Levofloxacin begins to work quickly, usually within the first 24 hours of taking it. However, it is important to take the full course of medication as prescribed in order to fully eliminate the infection.
Is Levofloxacin suitable for children?
Only in very specific cases. It is important to discuss the risks and benefits with your doctor to determine if Levofloxacin is suitable for children.
Will Levofloxacin treat a virus?
No, Levofloxacin is an antibiotic medication that is used to treat bacterial infections only. It will not be effective in treating viral infections.
Does Levofloxacin interact with any other medications?
Yes, Levofloxacin may interact with other medications, including certain antibiotics, antifungals, drugs used to treat high cholesterol levels, and drugs used to treat tuberculosis. It is important to discuss all medications you are taking with your doctor before taking Levofloxacin.
Does Levofloxacin cause weight gain?
No, Levofloxacin does not typically cause weight gain. Weight gain is more commonly associated with some of the other antibiotics, such as macrolides.
Can Levofloxacin be used to treat UTI?
Yes, Levofloxacin can be used to treat urinary tract infections (UTI). It is important to complete the full course of treatment for it to be effective.
What are the storage instructions for Levofloxacin?
Levofloxacin should be stored at room temperature, between 15-30°C (59-86°F), and away from light and moisture. It should also be kept out of the reach of children.
What are the possible allergic reactions to Levofloxacin?
Allergic reactions to Levofloxacin may include rashes, hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, stop taking Levofloxacin and seek medical attention immediately.
Can I take ibuprofen with Levofloxacin?
Yes, ibuprofen can be taken with Levofloxacin. It is important to follow the instructions of your doctor or pharmacist to avoid any interactions.
Should I take Levofloxacin with food?
Levofloxacin can be taken with or without food. However, for best absorption, it should be taken with a full glass of water.
Is Levofloxacin safe for pregnant women?
Levofloxacin is generally not recommended for use in pregnant women, as it can increase the risk of adverse effects on the developing baby. It is important to discuss the risks and benefits with your doctor before taking this medication.
Are there any interactions between Levofloxacin and other medications?
Yes, Levofloxacin can interact with other medications, including certain antibiotics, antifungal medications, and drugs used to treat high cholesterol levels. It is important to discuss all medications you are taking with your doctor before taking Levofloxacin.
Can Levofloxacin treat a bacterial infection?
Yes, Levofloxacin is an antibiotic medication used to treat a number of bacterial infections, including bronchitis, pneumonia, sinus infections, skin infections, and urinary tract infections.
How quickly will I start to feel better after taking Levofloxacin?
Most people start to feel better within 24 hours of taking Levofloxacin, however it is important to complete the full course of treatment for it to be effective.
Can I take Levofloxacin with dairy products?
No, it is best to avoid taking Levofloxacin with dairy products, such as milk, cheese, and yogurt, as they can decrease the effectiveness of Levofloxacin.
How long can I take Levofloxacin?
It is important to take Levofloxacin until you have completed the prescribed course of treatment, even if you start to feel better. Generally, Levofloxacin is taken for a period of 5 to 14 days.
Should I take Levofloxacin at the same time every day?
Yes, it is best to take Levofloxacin at the same time each day to maintain an even level of medication in your blood.
Does Levofloxacin have any interactions with alcohol?
Yes, it is not recommended to drink alcohol while taking Levofloxacin as it may increase the risk of side effects. It is best to check with your doctor first before drinking alcohol.
Can I take Levofloxacin while breastfeeding?
No, Levofloxacin is not recommended for use in breastfeeding women because it can pass into breast milk and may harm a nursing infant. It is important to discuss the risks and benefits with your doctor.
Can Levofloxacin cause stomach upset?
Yes, Levofloxacin can cause abdominal cramps, nausea, vomiting, and diarrhea. It is important to drink plenty of fluids to stay hydrated and talk to your doctor if the side effects persist.
Does Levofloxacin ever need to be refrigerated?
No, Levofloxacin does not need to be refrigerated. It should be stored at room temperature, between 15-30°C (59-86°F), and away from light and moisture.
Can Levofloxacin affect the liver?
Yes, Levofloxacin can cause liver damage in some people. It is important to report any changes in liver function to your doctor immediately.
Can I breastfeed while taking Levofloxacin?
No, Levofloxacin is not recommended for use in breastfeeding women because it can pass into breast milk and may harm a nursing infant. It is important to discuss the risks and benefits with your doctor.
Can I take vitamins while taking Levofloxacin?
Yes, you can take vitamins while taking Levofloxacin. However, it is best to check with your doctor first, as some vitamins may interact with Levofloxacin.
Can I take Levofloxacin with other medications?
Yes, Levofloxacin may be taken with other medications, however it is important to discuss all medications you are taking with your doctor to avoid any interactions.
Can Levofloxacin cause kidney damage?
Yes, Levofloxacin can cause kidney damage in some people. It is important to stay well hydrated while taking Levofloxacin and to report any changes in urine output to your doctor immediately.
Can Levofloxacin cause yeast infections?
Yes, taking Levofloxacin can upset the natural balance of bacteria in the body, which may lead to yeast infections. It is important to talk to your doctor if you experience any signs or symptoms of a yeast infection.
Does Levofloxacin cause drowsiness?
Yes, Levofloxacin can cause drowsiness and dizziness. It is important to avoid driving or operating machinery until you know how Levofloxacin will affect you.
Does Levofloxacin cause hair loss?
No, Levofloxacin is not known to cause hair loss. However, if you are taking other medications, it is important to talk to your doctor to see if they can cause hair loss.
Can Levofloxacin be used to treat skin infections?
Yes, Levofloxacin is an effective treatment for many types of skin infections, including bacterial skin