Lansoprazole, a brand name for a formulation containing essential Lansoprazole, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Lansoprazole, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.


Lansoprazole is an oral prescription drug which belongs to a family of medications called proton-pump inhibitors or PPIs. It is mainly used for treating acid related conditions such as heartburn, gastroesophageal reflux disease (GERD), and stomach and duodenal ulcers. It helps to reduce the acid build-up in the stomach by blocking the activity of some enzymes which produce acid.

Uses For

Lansoprazole is used to treat a variety of conditions related to acid in the stomach, including heartburn, gastroesophageal reflux disease (GERD), duodenal ulcer, and Zollinger-Ellison syndrome. It can also be used to prevent ulcers associated with long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Mechanism of Action

Lansoprazole works by inhibiting the pumps in the wall of the stomach which are responsible for producing acid to digest food. By blocking these pumps, it reduces the amount of acid in the stomach and helps to prevent acid reflux and other digestive complaints.

How Long Does it Take to Work?

Lansoprazole is usually effective within 24 hours and its full effect is seen usually within 7-14 days. It may take up to 3 weeks for the effects to be completely seen.


Lansoprazole is well absorbed from the gastrointestinal tract. It has an absolute bioavailability of approximately 93%.

Route of Elimination

Lansoprazole is eliminated primarily in the urine. The elimination half-life is about 1 hour and the clearance is approximately 0.2 L/h.


The usual adult dose for treating heartburn, duodenal ulcers, GERD, and Zollinger-Ellison syndrome is 15-30 mg once a day. For the treatment and prevention of stomach or duodenal ulcers associated with long-term NSAID use, the usual adult dose is 30 mg once daily.


Lansoprazole is available in capsule, tablet, and suspension form. It should be taken on an empty stomach, usually once a day. It should be taken before a meal, preferably in the morning.

Side Effects

Common side effects of lansoprazole may include headache, stomach pain, diarrhea, constipation, nausea, and rash. These effects usually improve after a few days, but should be reported to the doctor if they persist. Severe side effects such as fast or irregular heartbeat, intense abdominal pain, and difficulty breathing should be reported immediately to a doctor.


Lansoprazole is generally safe, but overdose can lead to serious adverse effects such as severe breathing problems, convulsions, and coma. It is important to take lansoprazole only at the prescribed dose and not exceed it.


Lansoprazole should be taken with caution in people with kidney or liver disease, history of heart attack or stroke, or any other medical condition. It should also be used with caution in children, pregnant or breastfeeding women. People taking lansoprazole should not drink alcohol or take other medications without consulting a doctor.


Lansoprazole may interact with other medications, vitamins, herbal supplements, or dietary supplements. It is important to tell the doctor about all the medications one is taking, including over-the-counter drugs, to avoid potential drug interactions.

Disease Interaction

Lansoprazole may interact with certain existing medical conditions such as liver or kidney disease, heart disease, or any other genetic or metabolic disorder. People with such conditions should consult with a doctor before taking lansoprazole.

Drug Interaction

There are several drugs which may interact with lansoprazole such as antifungal drugs, cancer drugs, anti-seizure drugs, blood thinners, and iron supplements. People should inform their doctor about all the drugs they are taking before taking lansoprazole.

Food Interactions

Certain food items such as dairy products, antacids, or calcium supplements can interfere with the absorption of lansoprazole and hence should be avoided. People should inform their doctor about any such interactions before taking lansoprazole.

Pregnancy Use

Lansoprazole should be used during pregnancy only if clearly needed and after consulting with a doctor. Its safety during pregnancy has not been established and hence should be used with caution. It should not be used in the first trimester unless clearly needed.

Lactation Use

Lansoprazole should be used during lactation only if clearly needed and after consulting with a doctor. It should not be used in combination with any other medication during lactation as it could increase the risk of adverse effects in the infant.

Acute Overdose

An acute overdose of lansoprazole may lead to symptoms such as convulsions, coma, extreme drowsiness, difficulty in breathing, and abdominal pain. Immediate medical attention is required in such cases.


Lansoprazole should not be used in people who are allergic to it or any of its ingredients. It should also not be used with certain drugs such as atazanavir and nelfinavir. People should inform their doctor if they are taking any other medication before taking lansoprazole.

Use Direction

Lansoprazole should be taken with water and on an empty stomach, usually once a day. It should be taken before a meal, preferably in the morning. Do not exceed the recommended dose or take this medicine for a longer period than recommended.

Storage Condition

Lansoprazole should be stored in a cool dry place, away from heat and direct light. It should be kept out of sight and reach of children.

Volume of Distribution

The volume of distribution of lansoprazole is 0.2 L/kg.

Half Life

The half-life of lansoprazole is approximately 1 hour.


The clearance of lansoprazole is approximately 0.2 L/h.

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