Kanaprim

Kanaprim Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Kanaprim is a brand name. Its generic name is Primaquine.

Introduction

Kanaprim is an antimalarial medication used to treat and prevent certain types of malaria. It is also used as a prophylaxis, which is used to prevent the further spread of malaria after initial treatment. Kanaprim belongs to a group of antimalarials called 8-amino-quinolines.

Uses For

Kanaprim is used to treat and prevent certain types of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is also used as a prophylaxis (preventive medication) against further accusations of malaria in travelers in areas that are infected with Plasmodium vivax and Plasmodium falciparum. Kanaprim should not be used in children under 8 years old.

Mechanism Of Action

Kanaprim works by interfering with two essential proteins involved in the synthesis of DNA in the malaria parasite. It inhibits the enzyme dihydrofolate reductase and interferes with the electron transport system, both of which are essential for the parasite to survive. Kanaprim also has a role in preventing the transmission of the malaria parasite to uninfected mosquito vectors.

How Long Does It Take To Work?

Kanaprim usually takes effect within 1-2 hours of ingestion. The effects of Kanaprim can last up to 48 hours, so it is important to take the medication as prescribed by a physician.

Absorption

Kanaprim is absorbed quickly and completely from the gastrointestinal tract. It has an apparent volume of distribution of 1.31 L/kg and an apparent bioavailability of 42%.

Route Of Elimination

Kanaprim is eliminated primarily by the kidneys. It has an elimination half-life of 23 hours.

Dosage

The recommended dosage for Kanaprim depends on the condition being treated. For prophylaxis, the usual dosage is 15mg orally once daily for 7 days. For treatment of acute malaria, the usual dosage is 15mg orally once daily for 14 days. It is important to take Kanaprim exactly as prescribed by a physician.

Administration

Kanaprim should be taken with food or a full glass of water. It should be taken at the same time each day to maintain an even level of medication in the bloodstream.

Side Effects

The most common side effects of Kanaprim include nausea, vomiting, headache, dizziness, loss of appetite, hair loss, hepatitis, rash, and anemia.

Toxicity

The toxic effects of Kanaprim include changes in behavior, disorientation, difficulty breathing, and seizures.

Precautions

Before taking Kanaprim, it is important to inform your physician if you have liver or kidney disease, blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or any allergies.

Interactions

Kanaprim can interact with other drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Disease Interactions

Kanaprim can worsen certain diseases, including cancer, diabetes, anemia, and liver or kidney disease.

Drug Interactions

Kanaprim can interact with certain drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Food Interactions

It is important to take Kanaprim with food to reduce the risk of interactions.

Pregnancy use

Kanaprim should not be used in pregnant women, as it may cause serious birth defects.

Lactationuse

Kanaprim should not be used while breastfeeding as it may be passed to the infant through breast milk.

Acute Overdose

The symptoms of an acute overdose may include severe abdominal pain, nausea, vomiting, seizures, and difficulty breathing. If you suspect an overdose, contact your local poison control center or emergency room immediately.

Contraindication

Kanaprim should not be used in people with certain conditions, including porphyria, G6PD deficiency, severe anemia, and hemolytic anemia.

Use Direction

Kanaprim should be taken as prescribed by a physician. Do not take more or less than the recommended amount.

Storage Condition

Kanaprim should be stored in a cool, dry place, at room temperature. Keep out of reach of children and pets.

Volume Of Distribution

Kanaprim has an apparent volume of distribution of 1.31 L/kg.

Half Life

Kanaprim has an elimination half-life of 23 hours.

Clearance

Kanaprim is eliminated primarily by the kidneys.

Here you find in details version of Kanaprim

Some Frequently Asked Questions About Kanaprim

What is Kanaprim?

Kanaprim is an antimalarial medication used to treat and prevent malaria infection.

How does Kanaprim work?

Kanaprim works by killing the malaria parasites in the liver. It also prevents the parasites from multiplying and spreading.

What is the active ingredient in Kanaprim?

The active ingredient in Kanaprim is primaquine phosphate.

How long does it take for Kanaprim to work?

Kanaprim typically begins to work within 24 hours of taking the medication.

What are the side effects of Kanaprim?

Typical side effects of Kanaprim include headache, nausea, dizziness, vomiting, loss of appetite, and abdominal pain.

Is Kanaprim safe to take during pregnancy?

Kanaprim should not be used during pregnancy, as it can cause harm to the unborn baby.

Is Kanaprim safe for children?

Kanaprim is generally not recommended for use in children under the age of 16.

Does Kanaprim interact with other medications?

Yes, Kanaprim can interact with other medications, including antacids, antibiotics, antivirals, and nonsteroidal anti-inflammatory drugs (NSAIDs).

What is the recommended dosage of Kanaprim?

The recommended dosage of Kanaprim is 0.5-1 tablet per day for adults and 0.25-0.5 tablet per day for children aged 16 and over.

What is the difference between Kanaprim and chloroquine?

Kanaprim is an antimalarial medication used to treat and prevent malaria infections, while chloroquine is an antimalarial medication used to treat and prevent malaria infections and also reduce inflammation in some autoimmune diseases.

Does Kanaprim need to be taken with food?

It is recommended to take Kanaprim with food to reduce the risk of stomach upset.

What should I do if I miss a dose of Kanaprim?

If you miss a dose of Kanaprim, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time.

How long should I take Kanaprim?

The length of time that Kanaprim should be taken depends on your individual medical condition. Your doctor will advise you on how long to take the medication.

Can I drink alcohol while taking Kanaprim?

It is not recommended to drink alcohol while taking Kanaprim, as it may increase the risk of side effects.

What is the generic name for Kanaprim?

The generic name for Kanaprim is primaquine phosphate.

Is Kanaprim an antibiotic?

No, Kanaprim is not an antibiotic; it is an antimalarial medication.

Can I buy Kanaprim over the counter?

No, Kanaprim is a prescription-only medication and cannot be bought over the counter.

Can Kanaprim be used to treat other conditions?

No, Kanaprim is only used to treat and prevent malaria infection.

What is the price of Kanaprim?

The price of Kanaprim varies depending on the manufacturer and dosage. Your pharmacy can provide you with the most up-to-date pricing information.

Can Kanaprim cause liver damage?

Yes, Kanaprim can cause liver damage in some individuals. If you have any liver problems, speak to your doctor before taking Kanaprim.

Does Kanaprim cause drowsiness?

Yes, Kanaprim can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

Does Kanaprim interact with birth control?

Yes, Kanaprim can interact with birth control. It is recommended to use another form of birth control while taking Kanaprim.

Does Kanaprim cause diarrhea?

Yes, Kanaprim can cause diarrhea in some individuals.

Is Kanaprim used to treat malaria?

Yes, Kanaprim is used to treat and prevent malaria infection.

Does Kanaprim cause weight gain?

No, Kanaprim does not typically cause weight gain.

Can I take Kanaprim with other medications?

It is important to tell your doctor about any other medications you are taking before taking Kanaprim, as some medications can interact with Kanaprim.

Will Kanaprim work against all strands of malaria?

Kanaprim has been shown to be effective against most strains of malaria; however, it may not work against all strains.

Does Kanaprim cause loss of appetite?

Yes, Kanaprim can cause loss of appetite in some individuals.

When should I start taking Kanaprim?

Your doctor will advise you as to when you should start taking Kanaprim. It is typically recommended to start taking the medication 1-2 days prior to traveling to a malaria-endemic region.

Is Kanaprim safe to take if I have kidney problems?

Yes, Kanaprim is generally considered safe to take if you have kidney problems; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take Kanaprim if I have high blood pressure?

Yes, Kanaprim can be taken if you have high blood pressure; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take Kanaprim for longer than the recommended time?

No, Kanaprim should only be taken for the recommended time, as it can cause serious side effects if taken for longer than recommended.

Can Kanaprim be split in half?

Yes, Kanaprim tablets can be safely split in half in order to reduce the dose taken.

What are the symptoms of an overdose on Kanaprim?

Symptoms of an overdose on Kanaprim may include headache, nausea, dizziness, vomiting, and abdominal pain.

Can Kanaprim cause an allergic reaction?

Yes, Kanaprim can cause an allergic reaction in some individuals. Stop taking the medication and seek medical attention if you experience any symptoms of an allergic reaction, such as rash, itching, or swelling.

Is Kanaprim effective against Plasmodium falciparum malaria?

Yes, Kanaprim has been found to be effective against Plasmodium falciparum malaria.

Does Kanaprim cause hair loss?

No, Kanaprim does not typically cause hair loss.

Can I take Kanaprim if I'm breastfeeding?

No, Kanaprim should not be taken while breastfeeding, as it can pass into breast milk and cause harm to the baby.

Does Kanaprim need to be taken with food?

It is recommended to take Kanaprim with food to reduce the risk of stomach upset.

What should I do if I get an upset stomach while taking Kanaprim?

If you experience an upset stomach while taking Kanaprim, try taking the medication with food. If your symptoms persist, speak to your doctor.

Does Kanaprim cause drowsiness?

Yes, Kanaprim can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

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