Jasoprim

Jasoprim Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Jasoprim is a brand name. Its generic name is Primaquine.

Introduction

Jasoprim is an antimalarial medication used to treat and prevent certain types of malaria. It is also used as a prophylaxis, which is used to prevent the further spread of malaria after initial treatment. Jasoprim belongs to a group of antimalarials called 8-amino-quinolines.

Uses For

Jasoprim is used to treat and prevent certain types of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is also used as a prophylaxis (preventive medication) against further accusations of malaria in travelers in areas that are infected with Plasmodium vivax and Plasmodium falciparum. Jasoprim should not be used in children under 8 years old.

Mechanism Of Action

Jasoprim works by interfering with two essential proteins involved in the synthesis of DNA in the malaria parasite. It inhibits the enzyme dihydrofolate reductase and interferes with the electron transport system, both of which are essential for the parasite to survive. Jasoprim also has a role in preventing the transmission of the malaria parasite to uninfected mosquito vectors.

How Long Does It Take To Work?

Jasoprim usually takes effect within 1-2 hours of ingestion. The effects of Jasoprim can last up to 48 hours, so it is important to take the medication as prescribed by a physician.

Absorption

Jasoprim is absorbed quickly and completely from the gastrointestinal tract. It has an apparent volume of distribution of 1.31 L/kg and an apparent bioavailability of 42%.

Route Of Elimination

Jasoprim is eliminated primarily by the kidneys. It has an elimination half-life of 23 hours.

Dosage

The recommended dosage for Jasoprim depends on the condition being treated. For prophylaxis, the usual dosage is 15mg orally once daily for 7 days. For treatment of acute malaria, the usual dosage is 15mg orally once daily for 14 days. It is important to take Jasoprim exactly as prescribed by a physician.

Administration

Jasoprim should be taken with food or a full glass of water. It should be taken at the same time each day to maintain an even level of medication in the bloodstream.

Side Effects

The most common side effects of Jasoprim include nausea, vomiting, headache, dizziness, loss of appetite, hair loss, hepatitis, rash, and anemia.

Toxicity

The toxic effects of Jasoprim include changes in behavior, disorientation, difficulty breathing, and seizures.

Precautions

Before taking Jasoprim, it is important to inform your physician if you have liver or kidney disease, blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or any allergies.

Interactions

Jasoprim can interact with other drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Disease Interactions

Jasoprim can worsen certain diseases, including cancer, diabetes, anemia, and liver or kidney disease.

Drug Interactions

Jasoprim can interact with certain drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Food Interactions

It is important to take Jasoprim with food to reduce the risk of interactions.

Pregnancy use

Jasoprim should not be used in pregnant women, as it may cause serious birth defects.

Lactationuse

Jasoprim should not be used while breastfeeding as it may be passed to the infant through breast milk.

Acute Overdose

The symptoms of an acute overdose may include severe abdominal pain, nausea, vomiting, seizures, and difficulty breathing. If you suspect an overdose, contact your local poison control center or emergency room immediately.

Contraindication

Jasoprim should not be used in people with certain conditions, including porphyria, G6PD deficiency, severe anemia, and hemolytic anemia.

Use Direction

Jasoprim should be taken as prescribed by a physician. Do not take more or less than the recommended amount.

Storage Condition

Jasoprim should be stored in a cool, dry place, at room temperature. Keep out of reach of children and pets.

Volume Of Distribution

Jasoprim has an apparent volume of distribution of 1.31 L/kg.

Half Life

Jasoprim has an elimination half-life of 23 hours.

Clearance

Jasoprim is eliminated primarily by the kidneys.

Here you find in details version of Jasoprim

Some Frequently Asked Questions About Jasoprim

What is Jasoprim?

Jasoprim is an antimalarial medication used to treat and prevent malaria infection.

How does Jasoprim work?

Jasoprim works by killing the malaria parasites in the liver. It also prevents the parasites from multiplying and spreading.

What is the active ingredient in Jasoprim?

The active ingredient in Jasoprim is primaquine phosphate.

How long does it take for Jasoprim to work?

Jasoprim typically begins to work within 24 hours of taking the medication.

What are the side effects of Jasoprim?

Typical side effects of Jasoprim include headache, nausea, dizziness, vomiting, loss of appetite, and abdominal pain.

Is Jasoprim safe to take during pregnancy?

Jasoprim should not be used during pregnancy, as it can cause harm to the unborn baby.

Is Jasoprim safe for children?

Jasoprim is generally not recommended for use in children under the age of 16.

Does Jasoprim interact with other medications?

Yes, Jasoprim can interact with other medications, including antacids, antibiotics, antivirals, and nonsteroidal anti-inflammatory drugs (NSAIDs).

What is the recommended dosage of Jasoprim?

The recommended dosage of Jasoprim is 0.5-1 tablet per day for adults and 0.25-0.5 tablet per day for children aged 16 and over.

What is the difference between Jasoprim and chloroquine?

Jasoprim is an antimalarial medication used to treat and prevent malaria infections, while chloroquine is an antimalarial medication used to treat and prevent malaria infections and also reduce inflammation in some autoimmune diseases.

Does Jasoprim need to be taken with food?

It is recommended to take Jasoprim with food to reduce the risk of stomach upset.

What should I do if I miss a dose of Jasoprim?

If you miss a dose of Jasoprim, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time.

How long should I take Jasoprim?

The length of time that Jasoprim should be taken depends on your individual medical condition. Your doctor will advise you on how long to take the medication.

Can I drink alcohol while taking Jasoprim?

It is not recommended to drink alcohol while taking Jasoprim, as it may increase the risk of side effects.

What is the generic name for Jasoprim?

The generic name for Jasoprim is primaquine phosphate.

Is Jasoprim an antibiotic?

No, Jasoprim is not an antibiotic; it is an antimalarial medication.

Can I buy Jasoprim over the counter?

No, Jasoprim is a prescription-only medication and cannot be bought over the counter.

Can Jasoprim be used to treat other conditions?

No, Jasoprim is only used to treat and prevent malaria infection.

What is the price of Jasoprim?

The price of Jasoprim varies depending on the manufacturer and dosage. Your pharmacy can provide you with the most up-to-date pricing information.

Can Jasoprim cause liver damage?

Yes, Jasoprim can cause liver damage in some individuals. If you have any liver problems, speak to your doctor before taking Jasoprim.

Does Jasoprim cause drowsiness?

Yes, Jasoprim can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

Does Jasoprim interact with birth control?

Yes, Jasoprim can interact with birth control. It is recommended to use another form of birth control while taking Jasoprim.

Does Jasoprim cause diarrhea?

Yes, Jasoprim can cause diarrhea in some individuals.

Is Jasoprim used to treat malaria?

Yes, Jasoprim is used to treat and prevent malaria infection.

Does Jasoprim cause weight gain?

No, Jasoprim does not typically cause weight gain.

Can I take Jasoprim with other medications?

It is important to tell your doctor about any other medications you are taking before taking Jasoprim, as some medications can interact with Jasoprim.

Will Jasoprim work against all strands of malaria?

Jasoprim has been shown to be effective against most strains of malaria; however, it may not work against all strains.

Does Jasoprim cause loss of appetite?

Yes, Jasoprim can cause loss of appetite in some individuals.

When should I start taking Jasoprim?

Your doctor will advise you as to when you should start taking Jasoprim. It is typically recommended to start taking the medication 1-2 days prior to traveling to a malaria-endemic region.

Is Jasoprim safe to take if I have kidney problems?

Yes, Jasoprim is generally considered safe to take if you have kidney problems; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take Jasoprim if I have high blood pressure?

Yes, Jasoprim can be taken if you have high blood pressure; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take Jasoprim for longer than the recommended time?

No, Jasoprim should only be taken for the recommended time, as it can cause serious side effects if taken for longer than recommended.

Can Jasoprim be split in half?

Yes, Jasoprim tablets can be safely split in half in order to reduce the dose taken.

What are the symptoms of an overdose on Jasoprim?

Symptoms of an overdose on Jasoprim may include headache, nausea, dizziness, vomiting, and abdominal pain.

Can Jasoprim cause an allergic reaction?

Yes, Jasoprim can cause an allergic reaction in some individuals. Stop taking the medication and seek medical attention if you experience any symptoms of an allergic reaction, such as rash, itching, or swelling.

Is Jasoprim effective against Plasmodium falciparum malaria?

Yes, Jasoprim has been found to be effective against Plasmodium falciparum malaria.

Does Jasoprim cause hair loss?

No, Jasoprim does not typically cause hair loss.

Can I take Jasoprim if I'm breastfeeding?

No, Jasoprim should not be taken while breastfeeding, as it can pass into breast milk and cause harm to the baby.

Does Jasoprim need to be taken with food?

It is recommended to take Jasoprim with food to reduce the risk of stomach upset.

What should I do if I get an upset stomach while taking Jasoprim?

If you experience an upset stomach while taking Jasoprim, try taking the medication with food. If your symptoms persist, speak to your doctor.

Does Jasoprim cause drowsiness?

Yes, Jasoprim can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

https://www.medicinesfaq.com/brand/jasoprim, http://classyfire.wishartlab.com/tax_nodes/C0000000, http://classyfire.wishartlab.com/tax_nodes/C0000002, http://classyfire.wishartlab.com/tax_nodes/C0001253, http://classyfire.wishartlab.com/tax_nodes/C0000053, http://classyfire.wishartlab.com/tax_nodes/C0000053, http://classyfire.wishartlab.com/tax_nodes/C0003999, http://classyfire.wishartlab.com/tax_nodes/C0000138, http://classyfire.wishartlab.com/tax_nodes/C0002458, http://classyfire.wishartlab.com/tax_nodes/C0000128, http://classyfire.wishartlab.com/tax_nodes/C0000089, http://classyfire.wishartlab.com/tax_nodes/C0004144, http://classyfire.wishartlab.com/tax_nodes/C0004139, http://classyfire.wishartlab.com/tax_nodes/C0004557, http://classyfire.wishartlab.com/tax_nodes/C0000469, http://classyfire.wishartlab.com/tax_nodes/C0004150, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:8405, http://www.hmdb.ca/metabolites/HMDB0015219, http://www.genome.jp/dbget-bin/www_bget?cpd:C07627, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4908, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508222, https://www.chemspider.com/Chemical-Structure.4739.html, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71542, https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=8687, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=8405, https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL506, http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000216, http://www.pharmgkb.org/drug/PA451103, https://www.drugs.com/cdi/primaquine.html, https://en.wikipedia.org/wiki/Primaquine,