Isoclox

Isoclox Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Isoclox is a brand name. Its generic name is Flucloxacillin.

Introduction

Isoclox is an antibiotic belonging to the penicillin family. It is used to treat infections caused by both Gram positive and Gram negative bacteria. It is available in most countries either as a generic drug or as branded versions.

Uses

Isoclox is primarily used to treat a wide range of bacterial infections including infections of the respiratory tract, skin, and urinary tract. It is also used to treat some sexually transmitted diseases such as gonorrhea.

Mechanism of Action

Isoclox works by inhibiting synthesis of bacterial cell wall. It attaches itself to enzymes responsible for cross-linking peptidoglycans molecules. This prevents these enzymes from functioning, effectively killing the bacterial cell.

How Long Does it Take to Work

Isoclox should start working within 12 to 24 hours of taking the medicine. However, it is important to take the medication as prescribed, and for the entire course of treatment, in order to get the full benefit.

Absorption

Isoclox is absorbed through the walls of the upper gastrointestinal tract. It is rapidly absorbed, reaching a peak concentration in one hour.

Route of Elimination

Isoclox is eliminated mainly through the urine. It is also excreted in bile.

Dosage

Isoclox is available in various dosage forms and strengths. The dosage usually depends on the type and severity of the infection being treated, as well as the patient’s age, weight, and kidney function. Common oral dosage forms and strengths include 250 mg, 500 mg, and 750 mg capsules. Common IV dosage forms and strengths include 500 mg, 1 g, and 2 g vials. Dosage should be determined by a doctor or pharmacist.

Administration

The medication can be taken orally with or without food, or it can be administered intravenously. If administered IV, it should be diluted with a compatible IV solution, such as normal saline, and administered slowly.

Side Effect

Common side effects of Isoclox may include nausea, diarrhea, vomiting, headache, and skin rash or itching. In rare cases it can cause severe allergic reactions or anaphylaxis. Serious side effects, such as watery or bloody diarrhea and flu-like symptoms, may require immediate medical attention.

Toxicity

Isoclox is considered to have relatively low toxicity when taken at the recommended dose. Overdose may lead to nausea, vomiting, abdominal pain, and other symptoms.

Precaution

Isoclox should be taken with caution if you are allergic to other medicines in the penicillin family, or if you have any other allergies. It should also be used with caution if you have preexisting kidney or liver problems.

Interaction

Isoclox can interact with some other medications. It is important to tell your doctor or pharmacist about all medications, vitamins, and supplements you are taking before starting to take this medication.

Disease Interaction

Isoclox should be used with caution if you have certain diseases such as diabetes, kidney disease, blood diseases, or liver disease.

Drug Interaction

Isoclox may interact with other medications such as antacids, birth control pills, and some blood pressure medications.

Food Interactions

Isoclox should be taken with food to minimize gastric irritation.

Pregnancy Use

Isoclox is not recommended for pregnant women due to the potential risk of harm to the fetus.

Lactation Use

Isoclox should not be used during lactation due to the potential risk of compromising the quality of breast milk.

Acute Overdose

In the case of an acute overdose, it is important to seek medical attention immediately. Symptoms may include nausea, vomiting, abdominal pain, and other symptoms.

Contraindication

Isoclox is contraindicated in patients who are allergic to penicillins, cephalosporins, or any other antibiotic.

Use Direction

Isoclox should be taken exactly as prescribed by your doctor or pharmacist. It should not be taken longer than the prescribed course of treatment as this increases the risk of developing bacterial resistance.

Storage Condition

Isoclox should be stored at room temperature and away from direct sunlight.

Volume of Distribution

Isoclox has a large volume of distribution. It is distributed into most body tissues and fluids, including saliva, semen, and cerebrospinal fluid.

Half Life

The half-life of flucloxacillin is 1.5 - 2 hours.

Clearance

Isoclox is cleared by both renal and non-renal mechanisms. It is primarily cleared by the kidneys, but it is also cleared by metabolism and excretion into bile.

Here you find in details version of Isoclox

Some Frequently Asked Questions About Isoclox

What is Isoclox?

Isoclox is a type of antibiotic, and it belongs to a group of medicines called 'penicillins'. It is used to treat bacterial infections, such as skin, chest, urine, and ear infections caused by susceptible organisms.

What is it used to treat?

Isoclox is used to treat bacterial infections, such as skin, chest, urinary, and ear infections, caused by susceptible organisms.

How does Isoclox work?

Isoclox works by stopping the bacteria from multiplying and killing them. It also helps the body's own natural defenses to fight the infection.

How quickly does Isoclox work?

Isoclox usually starts working within a few days and will often work within 24 hours, but it might take slightly longer to get rid of all the bacteria causing the infection.

How long should I take Isoclox?

It is important to take Isoclox for as long as your doctor has prescribed it for you. This is usually 5 to 10 days after your symptoms have gone. Stopping the medicine too soon could make the infection come back.

Is Isoclox the same as Penicillin?

No, Isoclox is a type of penicillin, but it is a more powerful form of penicillin that is used to treat more serious bacterial infections.

Can I drink alcohol while taking Isoclox?

It is not advisable to drink alcohol while taking any type of antibiotic. Alcohol can reduce the effectiveness of the antibiotic, and can also increase the risk of side effects such as nausea and vomiting.

Do I need to take Isoclox with food?

Isoclox does not need to be taken with food. However, if you experience any stomach discomfort or an upset stomach while taking the medicine, then taking it with food may help.

Can I take Isoclox while pregnant?

Generally, Isoclox is safe to take while pregnant, but it is important to speak to your doctor before taking any medication while pregnant.

Does Isoclox have any side effects?

Isoclox is generally well tolerated, but some people may experience side effects such as feeling sick, diarrhoea, stomach pain, and allergic reactions. Speak to your doctor if you experience any of these symptoms.

What should I do if I forget to take Isoclox?

If you forget to take a dose, take it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and take the next one when it is due. Do not take two doses at once.

Is Isoclox available over the counter?

No, Isoclox is a prescription-only medicine and is not available over the counter.

Is Isoclox safe for children?

Isoclox is generally safe for children, but it is important to speak to your doctor before giving any medication to a child.

Is Isoclox available as a generic medicine?

Yes, Isoclox is available in generic form and is usually cheaper than the branded version.

Is it safe to take Isoclox long-term?

It is not advised to take Isoclox for an extended period of time because it can cause antibiotic resistance in the body. If you have been prescribed Isoclox for a long-term infection, make sure to take it as directed.

Can Isoclox cause an allergic reaction?

Yes, an allergic reaction to Isoclox is possible. Symptoms of an allergic reaction can include an itchy rash, swelling of the face, tongue, and throat, difficulty breathing, and dizziness. If you experience any of these symptoms, seek medical help immediately.

Can Isoclox interact with other medicines?

Isoclox can interact with certain medicines, such as antacids, or other antibiotics. It is important to tell your doctor about any other medicines you are taking before starting Isoclox.

Can I take ibuprofen while taking Isoclox?

It is not advised to take ibuprofen while taking Isoclox as this can make it less effective. Speak to your doctor before taking any medicines while taking Isoclox.

Can Isoclox make my skin sensitive to the sun?

Yes, Isoclox can make your skin more sensitive to sunlight. It is important to wear sunscreen when outside and avoid direct exposure to sunlight.

Does Isoclox cause drowsiness?

No, Isoclox does not cause drowsiness. However, some people may experience dizziness, so it is important to be careful when driving or operating machinery.

Can I take Isoclox for a viral infection?

No, Isoclox is an antibiotic and only works against bacterial infections. It will not work against a viral infection and should not be taken for one.

What should I do if I experience any side effects with Isoclox?

If you experience any side effects while taking Isoclox, speak to your doctor as soon as possible. The side effects should go away after you stop taking the medicine, but if they persist, you should seek medical advice.

Can Isoclox be used to treat a sinus infection?

Isoclox can be used to treat a sinus infection if it is caused by bacteria, but it will not be effective against a sinus infection caused by a virus.

Can I take Isoclox if I have an intolerance to penicillin?

If you have an intolerance to penicillin, it is recommended that you do not take Isoclox. Speak to your doctor about an alternative medication.

What is the usual dosage of Isoclox?

The usual dose of Isoclox is 250-500 mg, taken every 6 hours for adult doses and 250-500 mg, taken every 8 hours for children's doses. The exact dose will depend on your medical condition and the severity of the infection.

Should Isoclox be taken with water?

Isoclox can be taken with or without water, but it is important to take it as directed on the patient information leaflet.

Can Isoclox be used to treat a urinary tract infection?

Yes, Isoclox is commonly used to treat urinary tract infections caused by susceptible bacteria.

Can Isoclox treat a tooth infection?

Yes, Isoclox can be used to treat a tooth infection if it is caused by susceptible bacteria.

Is Isoclox safe for elderly people?

Yes, Isoclox is generally safe for elderly people, as long as it is taken as directed. However, it is important to speak to your doctor before taking Isoclox if you are elderly, as they may need to adjust your dose.

Can Isoclox cause diarrhea?

Yes, Isoclox can cause diarrhea as a side effect. If you experience any other symptoms or the diarrhea persists, contact your doctor for advice.

Is Isoclox safe for people with kidney disease?

Isoclox is usually safe for people with kidney disease, but it is important to speak to your doctor before taking it. They may need to adjust your dose or monitor your kidney function.

Can I take Isoclox for a sore throat?

Isoclox is not usually prescribed for a sore throat, unless it is caused by a bacterial infection. If your sore throat is caused by a bacterial infection, speak to your doctor about the possibility of taking Isoclox.

Can I take Isoclox for a chest infection?

Yes, Isoclox is commonly used to treat chest infections caused by susceptible bacteria.

Can Isoclox treat an ear infection?

Yes, Isoclox can be used to treat ear infections caused by susceptible bacteria.

What are the storage instructions for Isoclox?

Isoclox should be stored in a cool, dry, and dark place, away from direct sunlight. It should also be kept away from children and pets.

Can I take Isoclox if I'm breast feeding?

It is generally safe to take Isoclox while breast feeding, but you should speak to your doctor for advice. There may be an alternative medicine that you can take.

Can Isoclox be taken with other antibiotics?

No, it is not recommended to take Isoclox with other antibiotics, as this can reduce its effectiveness. Speak to your doctor before taking any other medicines while taking Isoclox.

Does Isoclox cause weight gain?

No, Isoclox does not cause weight gain.

Can I take Isoclox with paracetamol?

Yes, it is safe to take paracetamol while taking Isoclox but do not take any other medicines, unless they have been approved by your doctor.

Is Isoclox safe for people with diabetes?

Yes, Isoclox is usually safe for people with diabetes, but it is important to speak to your doctor before taking any medication if you have diabetes.

Can I take Isoclox on an empty stomach?

Yes, Isoclox can be taken on an empty stomach. However, if you experience any stomach discomfort or an upset stomach while taking the medicine, then taking it with food may help.

Can Isoclox be used to treat a skin infection?

Yes, Isoclox can be used to treat skin infections caused by susceptible bacteria.