Iprost
Iprost Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Iprost is a brand name. Its generic name is Latanoprost.
Introduction
Iprost is an antiglaucoma drug, belonging to a group of drugs called prostaglandin analogs often used to reduce intraocular pressure. It works by decreasing the production of aqueous humor, thus reducing pressure inside the eye.Uses of Iprost
Iprost is used to reduce intraocular pressure in people with open-angle glaucoma. It can be used in those who have glaucoma or ocular hypertension, when other medicines have failed to reduce the intraocular pressure.Mechanism of Action
Iprost acts by increasing the outflow of aqueous humor from the anterior chamber of the eye to the sclera, thus reducing the intraocular pressure. It does this by increasing the activity of aqueous outflow pathways, like the trabecular meshwork and Schlemm's canal.How long does it take to work?
Iprost usually starts to work within a few hours after it is applied. However, it may take as long as three to four weeks before the full benefit of the drug is seen.Absorption, Route of elimination, Dosage, Administration
Iprost is absorbed through the conjunctiva and is metabolized in the liver by enzyme cytochrome P450. It is eliminated mainly through the urine and feces. The suggested dose for adults and children over 12 years of age is one drop in each affected eye daily, usually in the evening. For children under 12, the exact dosage should be prescribed by a doctor. Iprost should be administered as eye drops. To apply the drop, the user should start by washing their hands. The tip of the dropper should be gently placed to the eye and the solution should be released while the eye is closed. The medication should not be used more than once in a day.Side Effect
Iprost can cause side effects such as conjunctival hyperemia (redness of the eyes), burning sensation, blurred vision, dry eyes, cough, headache, nausea, and an increased amount of tears.Toxicity
Iprost is usually well tolerated, but may be toxic in cases of overdoses. Common symptoms of an overdose include headache, dizziness, nausea, vomiting, and difficulty breathing. If an overdose is suspected, the patient should be taken to the nearest hospital or poison control center immediately.Precautions
Iprost should be used with caution in patients who have severe allergic reactions, high blood pressure, and pterygium.It should also be used cautiously in patients with glaucoma caused by pseudoexfoliation or neovascularization.Interactions
There are no known drug interactions with latanoprost, but it may interact with other eye medications like ophthalmic beta blockers, carbonic anhydrase inhibitors, and miotics, so any current medications should be discussed with the doctor before use.Disease Interaction
Iprost may be toxic to those with severe viral, bacterial, or fungal infections affecting the eye. Severe narrow angle glaucoma, iritis, and cystoid macular edema may also present a risk.Drug Interaction
Iprost should not be used with drugs that lower intraocular pressure, like beta blockers or anticholinesterase drugs.Food Interactions
Foods that may interact with Iprost include salsalate, ascorbic acid, and sucralfate. Grapefruit may increase the absorption and concentration of latanoprost and should be avoided.Pregnancy Use
Iprost is not recommended for use during pregnancy. Animal studies have revealed evidence of embryo toxicity, so the benefits of use should be weighed against the potential risks.Lactation Use
It is not recommended for use during lactation as it is not known if latanoprost is present in breast milk and it could affect the baby.Acute Overdose
Symptoms of acute overdose can include headache, dizziness, fever, nausea, vomiting, and difficulty in breathing. In case of an overdose, medical attention should be sought immediately.Contraindication
Iprost is contraindicated in patients with hypersensitivity to the drug. It is also not recommended for use in those with neonates, infants, and children under 12 years of age.Use Directions
Iprost should be used as directed by the doctor or according to the instructions on the leaflet. The patient should ensure they use the medication in the evening only, as directed. The exact dosage should be determined by the doctor.Storage Condition
Iprost eye drops should be stored at a temperature between 2oC to 25oC. The dropper should be kept away from direct sources of sunlight and should be kept tightly closed when not in use.Volume of Distribution
Iprost has a volume of distribution of approximately 1 L/kg.Half Life
The half-life of latanoprost is approximately 6 hours.Clearance
Iprost has a clearance of approximately 0.11 L/h/kg.Here you find in details version of Iprost
Some Frequently Asked Questions About Iprost
What is Iprost?
Iprost is an eye medication that is used to treat glaucoma and ocular hypertension. It works by increasing the amount of fluid that drains from the eye, thereby decreasing pressure inside the eye.
Who should use Iprost?
Iprost is typically prescribed for people with glaucoma and ocular hypertension. Your healthcare provider will determine whether Iprost is the best treatment option for you based on your condition.
What should I do if I miss a dose of Iprost?
If you miss a dose, you should apply the missed dose as soon as you remember. If it is almost time for your next dose, you should skip the missed dose and go back to your regular dosing schedule.
How should Iprost be stored?
Iprost should be stored at room temperature between 15-30°C (59-86°F). Keep the medication away from light and excessive moisture.
How do I use Iprost?
Iprost should be used once daily in the evening. Wash your hands and face before using the medication. Place one drop of the medication directly onto the eye. Do not touch the dropper tip to the eye, eye lids, or any other surface. Close the eye for 2-3 minutes and then discard any remaining solution.
What should I do if I get Iprost in my mouth?
If you get Iprost in your mouth, you should rinse your mouth with water. Do not swallow the medication.
What should I do if I get Iprost in my eye?
If you get Iprost in your eye, you should flush the eye with warm water for 15 minutes. Contact your healthcare provider if there is no improvement in your symptoms.
How long does it take for Iprost to start working?
It typically takes up to a month of use for the full effects of Iprost to be seen. You may see some improvement in your symptoms within the first week.
How often should Iprost be used?
Iprost should be used once daily in the evening. It is important to use it at the same time each day to get the most benefit.
Can Iprost cause side effects?
Yes, Iprost can cause side effects. Common side effects include eye irritation, redness, and stinging. Serious side effects include sudden vision changes, eye swelling, worsening eye pain, or an increase in eye pressure. Contact your healthcare provider if you experience any serious side effects.
Can I wear contact lenses while using Iprost?
No, you should not wear contact lenses while using Iprost. You should wait at least 15 minutes after applying the medication before inserting your contact lenses.
Can I use Iprost with other eye medications?
Yes, you may be able to use Iprost with other eye medications. Talk to your healthcare provider about the medications you are taking and whether you can use them together.
Can I use Iprost while pregnant or nursing?
The safety of Iprost for use in pregnant or nursing women has not been established. Talk to your doctor before using this medication if you are pregnant or nursing.
Is Iprost over-the-counter?
No, Iprost is a prescription medication and is not available over-the-counter.
How long can I use Iprost?
Iprost should only be used for as long as your healthcare provider prescribes it. If you have further questions about its use, contact your healthcare provider.
Does Iprost cause weight gain?
No, Iprost does not cause weight gain.
Does Iprost cause dry eyes?
Iprost can cause dry eyes. Talk to your healthcare provider if you experience dry eyes with Iprost.
Can Iprost improve vision?
No, Iprost cannot improve vision. It can decrease eye pressure and help reduce the risk of vision loss due to glaucoma or ocular hypertension.
What should I do if I have an allergic reaction to Iprost?
If you experience a severe allergic reaction, stop using the medication and seek immediate medical attention. Symptoms of an allergic reaction include difficulty breathing, rash, itching or swelling of the face, tongue, or throat.
Can I drive or operate machinery while using Iprost?
Iprost may cause blurred vision and other vision changes. You should not drive or operate machinery until you know how the medication affects you.
How long does it take for Iprost to be absorbed by the body?
Iprost is rapidly absorbed by the body. Peak levels are typically reached within 1 hour of administration.
Is Iprost covered by insurance?
It depends on your insurance plan. Ask your insurance provider if Iprost is covered under your plan.
What should I do if I experience burning or stinging after using Iprost?
Iprost can cause burning and stinging when applied. This is a common side effect and should not last long. If the burning or stinging becomes severe or does not go away, contact your healthcare provider.
What should I do if Iprost is not working?
If Iprost is not working, it may be necessary to add or switch medications. Talk to your healthcare provider about your treatment options.
Can I wear eye makeup while using Iprost?
Yes, you can wear eye makeup while using Iprost. However, you should wait 10 minutes after applying the medication before applying makeup.
Can I use Iprost if I have allergies?
If you have allergies, you should talk to your doctor about the use of Iprost. Your doctor can determine if Iprost is safe for you to use.
Can I wear sunglasses while using Iprost?
Yes, you can wear sunglasses while using Iprost. However, you should apply the medication first and wait 30 minutes before putting on your sunglasses.
Can I use Iprost on my lower eyelid?
No, Iprost should only be used as directed by your healthcare provider.
Can I use Iprost if I have conjunctivitis?
No, Iprost should not be used if you have conjunctivitis. Talk to your healthcare provider about your treatment options.
Can Iprost be used in the morning?
No, Iprost should only be used once daily in the evening.
Is there a generic form of Iprost?
Yes, there is a generic form of Iprost available. Talk to your healthcare provider about the form that is right for you.
Is Iprost available in different concentrations?
Yes, Iprost is available in different concentrations. Your healthcare provider will determine the best concentration for you based on your condition.
Can Iprost cause an increase in eye pressure?
Iprost can cause an increase in eye pressure in some people. If you experience an increase in eye pressure, contact your healthcare provider.
What should I do if I experience discoloration of my eyelids or iris while using Iprost?
Iprost can cause discoloration of the eyelids or iris. If discoloration occurs, contact your healthcare provider.
Can I use Iprost if I have had eye surgery?
Yes, you may be able to use Iprost if you have had eye surgery. Talk to your doctor before using this medication after eye surgery.
Can I use Iprost if I have a corneal abrasion?
No, Iprost should not be used if you have a corneal abrasion. Talk to your healthcare provider about other treatment options.
Can Iprost be used in children?
The safety and efficacy of Iprost for use in children has not been established. Talk to your healthcare provider before giving Iprost to a child.
Can skin contact with Iprost cause side effects?
Yes, skin contact with Iprost may cause side effects. Wash the area with soap and water and contact your healthcare provider if skin irritation or discoloration occurs.
Can I wear contact lenses after using Iprost?
Yes, you can wear contact lenses after using Iprost. However, you should wait at least 15 minutes before inserting the contact lenses.
Does Iprost need to be refrigerated?
No, Iprost does not need to be refrigerated. It should be stored at room temperature between 15-30°C (59-86°F). Keep the medication away from light and excessive moisture.
What should I do if I experience eye pain while using Iprost?
If you experience eye pain while using Iprost, contact your healthcare provider. They may recommend suspending the medication or switching to a different medication.