Indelix SR

Indelix SR Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Indelix SR is a brand name. Its generic name is Indapamide.

Indelix SR

Indelix SR is a medication used to treat high blood pressure and swelling due to fluid build up. It is a thiazide diuretic, which works by decreasing salt and water retention in the body. Indelix SR is used to control hypertension and was approved by the US Food and Drug Administration (FDA) in 1982 and is available in both tablet and capsule form.

Uses For

Indelix SR is used to treat hypertension, or high blood pressure, by blocking the reabsorption of salt and water in the kidney. This causes an increased production of urine, which results in lower blood pressure levels.

Mechanism of Action

Indelix SR works by blocking the reabsorption of salt and water in the kidneys. This stimulates increased urine production, leading to lower blood pressure levels. Indelix SR reduces the amount of water retained in the body by the kidneys and directly affects the heart by decreasing preload, therefore decreasing the amount of work the heart needs to do.

How Long Does It Take to Work?

Indelix SR typically begins to work within 4 to 6 hours. Patients taking indapamide should maintain close contact with their doctor to monitor blood pressure and symptoms for up to 8 weeks to ensure the medication is working as intended.

Absorption

Indelix SR is rapidly and almost completely absorbed in the small intestine. It is highly protein bound in the plasma and can cross the placenta.

Route of Elimination

Indelix SR is metabolized in the liver and eliminated through the kidneys, primarily via the urine.

Dosage

Indelix SR is available as 2.5 and 5 mg tablets. It is usually taken once daily in either a 2.5 or 5 mg dose. Your doctor will determine which dose is most appropriate for your situation.

Administration

Indelix SR can be taken with or without food. It is important to take the medication as prescribed by your doctor or pharmacist and follow all directions when taking it.

Side Effect

Common side effects include dizziness, lightheadedness, headache, diarrhea, nausea, vomiting, and low blood sugar. More serious side effects may include electrolyte abnormalities, low blood pressure, fever, rash, abdominal pain, and jaundice.

Toxicity

Indelix SR is generally well tolerated. The most common side effects include dizziness, lightheadedness, headache, diarrhea, nausea, vomiting, and low blood sugar. Rarely, more serious side effects may occur, including electrolyte abnormalities, low blood pressure, fever, rash, abdominal pain, and jaundice. If any of these side effects occur, contact your doctor immediately.

Precautions

Indelix SR should not be used in patients with allergies to it or sulfonamide drugs. Additionally, the medication should also not be used in patients with extreme electrolyte imbalance or severe kidney disease. Patients should not take the medication if they are pregnant or breastfeeding. Common sense precautions should be taken, as the medication may interact with other drugs or treatments.

Interactions

Indelix SR may interact with other medications. For example, it has been shown that indapamide can interact with ACE inhibitors, calcium channel blockers, and other diuretics. Some medications, such as lithium and non-steroidal anti-inflammatory drugs (NSAIDs), may increase the risk of side effects when taken with indapamide. Always consult a healthcare professional before taking any medication in combination with indapamide.

Disease Interactions

Indelix SR can interact with certain diseases, such as diabetes mellitus, gout, and a history of kidney or liver disease. It can also interact with certain autoimmune diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis. Patients with these conditions should discuss the risks and benefits with their doctor.

Drug Interactions

Indelix SR may interact with other medications. For example, it can interact with ACE inhibitors, calcium channel blockers, and other diuretics. It may also interact with certain medications, such as SSRIs and tricyclic antidepressants, herbal products, and barbiturates. Always consult a healthcare professional before taking any medication in combination with indapamide.

Food Interactions

Indelix SR may interact with certain foods. The drug may decrease the absorption of potassium, which can interfere with the effects of high-potassium foods such as oranges and bananas. Additionally, alcohol and caffeine may increase the risk of side effects. Speak to your doctor about your dietary restrictions before taking indapamide.

Pregnancy Use

Indelix SR is not recommended in pregnant women. The risk versus benefit should be assessed and discussed with a healthcare professional before taking the medication.

Lactation Use

Indelix SR is not recommended in breastfeeding women. The risk versus benefit should be assessed and discussed with a healthcare professional before taking the medication.

Acute Overdose

If an overdose of indapamide is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose include electrolyte imbalances, hypotension, and dehydration.

Contraindication

Indelix SR is contraindicated in patients with allergies to it or sulfonamide drugs, and in patients with extreme electrolyte imbalance or severe kidney disease. Additionally, the medication should not be used in pregnant or breastfeeding women.

Use Direction

Indelix SR should be taken as directed by your doctor. It is usually taken once daily, in either a 2.5 or 5 mg dose, depending on your individual needs. It can be taken with or without food. If any side effects occur, contact your doctor immediately.

Storage Condition

Indelix SR should be stored at room temperature away from direct light and moisture. Do not store in the bathroom or near any other source of heat or humidity.

Volume of Distribution

The volume of distribution of indapamide is approximately 0.6 to 0.9 liters per kilogram of body weight.

Half Life

The half-life of indapamide is approximately 18 to 24 hours.

Clearance

The clearance of indapamide is approximately 0.15 to 0.40 ml/min per kg.

Here you find in details version of Indelix SR

Some Frequently Asked Questions About Indelix SR

What is indapamide?

Indelix SR is a diuretic (water pill) that is used to treat high blood pressure and edema in people with congestive heart failure. It is also used to treat salt and water retention in people with certain kidney conditions.

How long does it take for indapamide to work?

The effects of indapamide usually start within 1 to 2 hours of taking the medication, and its effect can last up to 24 hours.

What are the possible side effects of taking indapamide?

Common side effects of taking indapamide include headaches, dizziness, low blood pressure, and fatigue. More serious side effects include kidney problems, changes in electrolyte levels, and liver damage. Talk to your doctor about any side effects you may experience.

What is the recommended dosage of indapamide?

The recommended dosage of indapamide varies depending on your medical condition and other factors. Your doctor will determine the correct dose for you.

Should I take indapamide with food or without food?

It is best to take indapamide with food or a full glass of water to reduce the risk of side effects. Talk to your doctor or pharmacist about how and when to take your medication.

Is it safe to drink alcohol while taking indapamide?

It is not recommended to drink alcohol while taking indapamide as it may increase the risk of side effects. Talk to your doctor or pharmacist before drinking alcohol while taking this medication.

What should I do if I miss a dose of indapamide?

If you miss a dose of indapamide, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not take an extra dose to make up for the missed one.

What medications interact with indapamide?

Some medications that interact with indapamide include aspirin, ibuprofen, diuretics, laxatives, potassium supplements, lithium, certain antibiotics, NSAIDs, antifungals, and certain anti-seizure medications. Talk to your doctor about all the medications you are taking.

Are there any lifestyle changes I should make while taking indapamide?

It is important to eat a healthy diet and exercise regularly while taking indapamide. This can help reduce the risk of side effects and improve the effectiveness of the medication. Your doctor may have additional suggestions.

Is indapamide safe for pregnant women to take?

Indelix SR should generally be avoided during pregnancy, unless the benefits outweigh the risks. Talk to your doctor about your options.

Does indapamide have any long-term side effects?

Long-term usage of indapamide can cause a decrease in potassium levels and an increased risk of kidney or liver problems. Talk to your doctor about the potential long-term side effects of this medication.

What should I do if I experience any severe side effects while taking indapamide?

If you experience any severe side effects such as confusion, difficulty breathing, or yellowing of the skin while taking indapamide, seek medical attention as soon as possible.

Are there any other diuretic medications I can take beside indapamide?

Yes, there are other diuretic medications available such as furosemide, bumetanide, and torsemide. Talk to your doctor about which diuretic would be best for you.

Are there any other medical conditions I should tell my doctor about before taking indapamide?

Inform your doctor if you have any other medical conditions, especially heart or kidney disease, or if you have diabetes, gout, or liver disease. Let your doctor know if you are pregnant or planning to become pregnant.

Can I buy indapamide over the counter?

No, indapamide is a prescription medication and must be prescribed by a doctor. Do not attempt to purchase this medication without a prescription.

Can I take indapamide and ibuprofen together?

It is generally not recommended to take indapamide and ibuprofen together due to the risk of drug interaction and increased side effects. Talk to your doctor or pharmacist about other pain relievers you can take while taking indapamide.

Can indapamide be taken with other blood pressure medications?

Yes, indapamide can be taken with other blood pressure medications. However, talk to your doctor first to ensure that this combination is safe for you.

What should I do if I experience an allergic reaction to indapamide?

If you experience any signs of an allergic reaction such as hives, difficulty breathing, or swelling of the face or throat, seek medical attention as soon as possible.

How long does it take for indapamide to start working?

The effects of indapamide usually start within 1 to 2 hours of taking the medication, and its effect can last up to 24 hours.

Is indapamide safe for elderly people to take?

Yes, indapamide is safe for elderly people to take. However, they may be more prone to side effects, and the dosage may need to be adjusted. Talk to your doctor about the best dosage for you.

Is indapamide habit-forming?

No, indapamide is not habit-forming. However, it’s important to take the medication as prescribed by your doctor.

Can indapamide be used to treat heart failure?

Yes, indapamide can be used to treat heart failure by decreasing the amount of fluid in the body and making it easier for the heart to pump blood. Talk to your doctor about whether this medication is right for you.

Is indapamide effective in treating high blood pressure?

Yes, indapamide is effective in treating high blood pressure by helping to reduce the amount of fluid in the body, which helps lower blood pressure. Talk to your doctor about whether this medication is right for you.

Can indapamide help with water retention?

Yes, indapamide can help treat water retention and edematous conditions caused by certain conditions such as congestive heart failure or kidney failure. Talk to your doctor about whether this medication is right for you.

Can I take indapamide while breastfeeding?

Indelix SR may pass into breast milk, so it’s best to talk to your doctor before taking this medication while breastfeeding. Your doctor will determine the best course of action for you.

How long does it take for indapamide to start working?

The effects of indapamide usually start within 1 to 2 hours of taking the medication, and its effect can last up to 24 hours.

Can I take indapamide if I have kidney disease?

Indelix SR is sometimes used to treat salt and water retention in people with certain kidney conditions, however, you should talk to your doctor first before taking this medication. Your doctor will determine the best course of action for you.

Does indapamide cause dry mouth?

Yes, dry mouth is a possible side effect of taking indapamide. Make sure to drink plenty of fluids throughout the day to help reduce this symptom.

What should I do if I experience nausea or vomiting while taking indapamide?

If you experience nausea or vomiting while taking indapamide, talk to your doctor about adjusting the dosage or switching to a different medication. If these symptoms persist, seek medical attention as soon as possible.

How often should I take indapamide?

The frequency of your indapamide dosage depends on your medical condition and other factors. Your doctor will determine the correct frequency of your dosage.

How should I store indapamide?

Indelix SR should be stored at room temperature, away from moisture and heat. Keep the medication in a safe place where children and pets cannot access it.

Is indapamide safe for people with diabetes?

Yes, indapamide is safe for people with diabetes. However, talk to your doctor first to make sure this medication is right for you. Your doctor may need to monitor your blood sugar levels more closely while you take this medication.

Can indapamide cause fatigue?

Yes, fatigue is a possible side effect of taking indapamide. If you experience this symptom, talk to your doctor about adjusting your dosage or switching to a different medication.

Is indapamide a diuretic?

Yes, indapamide is a diuretic (water pill) that is used to treat high blood pressure and edema in people with congestive heart failure. It is also used to treat salt and water retention in people with certain kidney conditions.

Can indapamide cause an increase in potassium levels?

No, indapamide can actually cause a decrease in potassium levels. Talk to your doctor about monitoring your potassium levels while taking this medication.

How long does indapamide stay in the body?

The half-life of indapamide is about 6 – 12 hours, so it typically stays in your system for 1 to 2 days.

Who should not take indapamide?

People with severe liver or kidney disease, those with low blood pressure, or those allergic to indapamide or any other sulfonamide-based medication should not take indapamide. Talk to your doctor before taking this medication.