Hepamerz

Hepamerz Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Hepamerz is a brand name. Its generic name is L-Ornithine L-Aspartate + Pancrelipase.

Introduction

L-Ornithine L-Aspartate in combination with Pancrelipase is an oral medication used to treat exocrine pancreatic insufficiency (EPI). EPI is a condition in which the pancreas is unable to produce enough enzymes to digest food, resulting in impaired digestion and absorption of nutrients. L-Ornithine L-Aspartate and Pancrelipase help to supplement the natural enzymes produced by the pancreas and increase digestion and absorption of nutrients.

Uses For

L-Ornithine L-Aspartate and Pancrelipase are used to treat exocrine pancreatic insufficiency. This condition is caused by a lack of pancreatic enzymes, which can lead to poor digestion and absorption of nutrients.

Mechanism of Action

L-Ornithine L-Aspartate is an amino acid that works to increase the natural production of the enzymes produced by the pancreas. Pancrelipase is a pancreatic enzyme that helps to supplement the natural enzymes produced by the pancreas. Together, they help to increase digestion and absorption of nutrients in patients with exocrine pancreatic insufficiency.

How Long Does it Take to Work?

The effects of taking L-Ornithine L-Aspartate in combination with Pancrelipase can be felt within 24-48 hours after starting treatment.

Absorption

L-Ornithine L-Aspartate is readily absorbed through the gastrointestinal (GI) tract, whereas Pancrelipase is slowly absorbed.

Route of Elimination

L-Ornithine L-Aspartate is eliminated primarily through the urine, whereas Pancrelipase is eliminated through the feces.

Dosage

L-Ornithine L-Aspartate in combination with Pancrelipase is available in capsule and tablet form. The usual dosage range for adults is one capsule or tablet taken two to three times daily, 30 minutes before meals and at bedtime. The dosage range for children depends on the child’s age and weight. It is recommended that the dosage be determined by a healthcare professional.

Administration

L-Ornithine L-Aspartate and Pancrelipase should be taken by mouth as directed by a healthcare professional. The capsules or tablets should be swallowed whole with a full glass of water.

Side Effects

Common side effects of L-Ornithine L-Aspartate and Pancrelipase include nausea, vomiting, diarrhea, abdominal pain, flatulence, and rash.

Toxicity

L-Ornithine L-Aspartate and Pancrelipase are generally well tolerated when taken at the recommended doses. At higher than recommended doses, the possibility of toxicity increases.

Precaution

L-Ornithine L-Aspartate and Pancrelipase should not be taken by those with known hypersensitivity to any of the ingredients. It should also not be taken by those with an active or suspected pancreatic disease, advanced renal disease, or severe bowel obstruction.

Interaction

L-Ornithine L-Aspartate and Pancrelipase may interact with other medications, especially those that affect gastric emptying or absorption. It is recommended that one speaks to their healthcare provider about potential interactions.

Disease Interaction

L-Ornithine L-Aspartate and Pancrelipase should not be taken by those with active or suspected pancreatic disease, advanced renal disease, or severe bowel obstruction.

Drug Interaction

L-Ornithine L-Aspartate and Pancrelipase may interact with other medications, especially those that affect gastric emptying or absorption. It is recommended that one speaks to their healthcare provider about potential interactions.

Food Interactions

L-Ornithine L-Aspartate and Pancrelipase may interact with certain foods. One should consult their healthcare provider for a list of foods to avoid or limit while taking this medication.

Pregnancy Use

L-Ornithine L-Aspartate and Pancrelipase is not recommended for use during pregnancy. It is not known if this medication will harm a developing fetus.

Lactation Use

L-Ornithine L-Aspartate and Pancrelipase is not recommended for use during breastfeeding. It is not known if this medication passes into breast milk and could cause harm to a nursing baby.

Acute Overdose

An acute overdose of L-Ornithine L-Aspartate and Pancrelipase can be dangerous and cause severe side effects. If an overdose is suspected, contact a healthcare provider immediately.

Contraindication

L-Ornithine L-Aspartate and Pancrelipase should not be used by those with known hypersensitivity to any of the ingredients.

Use Direction

L-Ornithine L-Aspartate in combination with Pancrelipase should be taken as directed by a healthcare professional. The capsules or tablets should be taken with a full glass of water and swallowed whole.

Storage Condition

L-Ornithine L-Aspartate with Pancrelipase should be stored in a cool, dry place away from direct sunlight.

Volume of Distribution

The volume of distribution of L-Ornithine L-Aspartate with Pancrelipase is not known.

Half Life

The half-life of L-Ornithine L-Aspartate with Pancrelipase is not known.

Clearance

The clearance of L-Ornithine L-Aspartate with Pancrelipase is not known.

Here you find in details version of Hepamerz

Some Frequently Asked Questions About Hepamerz

What is Hepamerz?

L-ornithine L-aspartate + pancrelipase is an oral osmotic drug formulation commonly used in the treatment of exocrine pancreatic insufficiency. It is composed of a combination of L-ornithine L-aspartate, which helps to reduce ammonia in the body, and a pancreatic enzyme, which helps to break down fats, proteins, and carbohydrates.

What is Exocrine Pancreatic Insufficiency (EPI)?

Exocrine Pancreatic Insufficiency (EPI) is a disorder characterized by the lack of digestive enzymes produced by the pancreas. This condition can lead to malabsorption of food, resulting in weight loss, diarrhea, and abdominal pain.

How effective is Hepamerz in treating Exocrine Pancreatic Insufficiency?

Studies have shown that L-ornithine L-aspartate + pancrelipase is beneficial in treating EPI. It has been found to improve digestive enzyme activity, reduce abdominal pain, and reduce malabsorption. However, it is important to discuss any treatment plans with your doctor before taking any medications.

What are the side effects of Hepamerz?

Common side effects of L-ornithine L-aspartate + pancrelipase include abdominal pain, diarrhea, nausea, and headache. If you experience any of these symptoms, it is important to speak with your doctor right away.

Who should not take Hepamerz?

L-ornithine L-aspartate + pancrelipase is not recommended for those who are allergic to any of the medications or substances used in the formulation. It is also not recommended for pregnant or breastfeeding women, children, and those with liver or kidney disease.

What are the possible drug interactions with Hepamerz?

Drug interactions are possible with L-ornithine L-aspartate + pancrelipase. Common drug interactions include antacids, antibiotics, and digoxin. It is important to tell your doctor about all medications and supplements you are taking before starting this medication.

What should I do if I miss a dose of Hepamerz?

If you miss a dose of L-ornithine L-aspartate + pancrelipase, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next one as scheduled. Do not double up on doses to make up for a missed dose.

Can I drink alcohol while taking Hepamerz?

It is not recommended to drink alcohol while taking L-ornithine L-aspartate + pancrelipase. Alcohol can decrease the effectiveness of the medication and should be avoided.

How long does Hepamerz take to work?

It typically takes around 2 to 4 weeks for the medication to reach its full effect. During this time you may experience some side effects, such as diarrhea or abdominal cramps, which usually dissipate after a few days.

How should Hepamerz be stored?

L-ornithine L-aspartate + pancrelipase should be stored in a dry, cool place away from direct sunlight. It should be protected from moisture and direct heat. Keep it out of reach of children and pets.

What are the ingredients in Hepamerz?

L-ornithine L-aspartate + pancrelipase contains the active ingredients L-ornithine L-aspartate and pancrelipase. It also contains the inactive ingredients sodium bicarbonate, sodium chloride, and water.

How often should I take Hepamerz?

It is important to take L-ornithine L-aspartate + pancrelipase as prescribed by your doctor. Typically the medication is taken twice daily, but it may be taken more or less often depending on your doctor's recommendation.

What should I do if I experience an allergic reaction to Hepamerz?

If you experience an allergic reaction while taking this medication, stop taking it immediately and call your doctor. Common signs of an allergic reaction include hives, itching, rash, difficulty breathing, and swelling of the face, tongue, or throat.

Is there a generic version of Hepamerz available?

Currently, there is no generic version of L-ornithine L-aspartate + pancrelipase available. However, generic versions of the individual ingredients, L-ornithine L-aspartate and pancrelipase, may be available.

Does Hepamerz come in different strengths?

L-ornithine L-aspartate + pancrelipase is available in two different strengths, 2.4 g and 4.8 g. Depending on your doctor's recommendation, you may be prescribed either strength.

Does Hepamerz interact with other medications?

Yes, L-ornithine L-aspartate + pancrelipase can interact with other medications. Common medications that can interact with this drug include antacids, antibiotics, and digoxin. It is important to tell your doctor about all medications and supplements you are taking before using this medication.

What can I do to make sure that Hepamerz is effective?

It is important to take L-ornithine L-aspartate + pancrelipase as prescribed. It is also important to maintain a healthy diet with plenty of fruits, vegetables, and whole grains. Additionally, it is important to avoid foods that can exacerbate symptoms, such as processed foods, high-fat foods, dairy products, and refined sugar.

Can Hepamerz be taken with other medications?

Yes, it is possible to take L-ornithine L-aspartate + pancrelipase with other medications. However, it is important to tell your doctor about all medications and supplements you are taking before using this medication, as drug interactions are possible.

What else can I do to help manage Exocrine Pancreatic Insufficiency?

In addition to taking medication, it is important to maintain a healthy lifestyle. Eating a balanced diet with plenty of fruits, vegetables, and whole grains is important. Additionally, getting regular exercise and avoiding or limiting alcohol and caffeine can also help to manage EPI.

Is Hepamerz safe for long-term use?

Yes, L-ornithine L-aspartate + pancrelipase is considered to be safe for long-term use. However, it is important to speak with your doctor if you have any concerns about taking this medication for extended periods of time.

Can Hepamerz be taken with food?

Yes, L-ornithine L-aspartate + pancrelipase can be taken with food. It is important to take the medication as prescribed by your doctor. If you are unsure, speak with your doctor or pharmacist.

Will Hepamerz cure Exocrine Pancreatic Insufficiency?

No, L-ornithine L-aspartate + pancrelipase is not a cure for Exocrine Pancreatic Insufficiency. It is used to treat the symptoms of EPI and improve digestive enzyme activity and calcium absorption. It is important to maintain a healthy lifestyle and take other medications as prescribed in order to manage EPI.

What should I do if I accidentally take too much Hepamerz?

If you accidentally take too much L-ornithine L-aspartate + pancrelipase, it is important to seek medical attention right away. Symptoms of an overdose of this medication can include abdominal pain, diarrhea, nausea, and vomiting.

Are there any foods I should avoid while taking Hepamerz?

It is important to maintain a balanced diet while taking L-ornithine L-aspartate + pancrelipase. However, it is important to avoid processed foods, high-fat foods, dairy products, and refined sugar. Additionally, it is important to speak with your doctor before introducing any new foods into your diet.

What is the recommended dosage for Hepamerz?

The recommended dosage of L-ornithine L-aspartate + pancrelipase varies depending on factors such as age, weight, medical history, and other medical conditions. It is important to follow your doctor's instructions carefully.

What medical conditions are contraindicated with Hepamerz?

L-ornithine L-aspartate + pancrelipase is not recommended for those who are allergic to any of the ingredients in the formulation. It is also not recommended for pregnant or breastfeeding women, children, and those with liver or kidney disease.

Should I take Hepamerz if I have an ulcer?

You should not take L-ornithine L-aspartate + pancrelipase if you have an ulcer. Taking this medication when you have an ulcer can increase the risk of abdominal pain, nausea, and vomiting.

Can I take Hepamerz with ibuprofen?

It is not recommended to take L-ornithine L-aspartate + pancrelipase with ibuprofen. Drug interactions are possible with this medication, and it is important to speak with your doctor before taking any medication.

Does Hepamerz help with digestive enzyme activity?

Yes, L-ornithine L-aspartate + pancrelipase helps to improve digestive enzyme activity. This can help to improve absorption of nutrients from food, resulting in improved overall health.

Should I take Hepamerz with food?

Yes, it is recommended to take L-ornithine L-aspartate + pancrelipase with food. Speak with your doctor or pharmacist to find out the best way to take this medication.

Are there any alternatives to taking Hepamerz?

Yes, there are alternatives to taking L-ornithine L-aspartate + pancrelipase. In some cases, a doctor may prescribe the individual active ingredients, L-ornithine L-aspartate and pancrelipase in separate tablets. Additionally, lifestyle changes such as following a healthy diet and getting regular exercise may also help to manage symptoms.

Can pregnant women take Hepamerz?

No, pregnant women should not take L-ornithine L-aspartate + pancrelipase. This medication is not recommended for pregnant women. Speak with your doctor for further information.