Glimepirida Ciclum

Glimepirida Ciclum, a brand name for a formulation containing essential Glimepiride, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Glimepirida Ciclum, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.

Introduction

Glimepirida Ciclum is an oral anti-diabetic drug used in the management of type 2 Diabetes mellitus. It helps reduce the blood glucose levels by increasing the production of insulin by the pancreas. Glimepirida Ciclum works by stimulating the release of insulin produced in the pancreatic beta cells.

Uses

Glimepirida Ciclum is used in the management of type 2 diabetes mellitus. It is used in combination with diet and exercise to improve blood sugar control.

Mechanism of Action

Glimepirida Ciclum belongs to a class of medications known as sulfonylureas. It works by stimulating the release of insulin produced in the pancreatic beta cells.

How Long Does It Take To Work?

It usually takes Glimepirida Ciclum about 2 to 4 weeks to show its full effect as it takes time for the body to adjust to the new medicine.

Absorption

Glimepirida Ciclum is quickly and almost completely absorbed from the gastrointestinal tract. It reaches peak concentrations in the plasma after about 2-4 hours post-ingestion.

Route of Elimination

The majority of Glimepirida Ciclum is eliminated in the urine, either as unchanged drug or in the form of metabolites. A small part of the drug is eliminated through the feces.

Dosage

Glimepirida Ciclum is available in the form of tablets ranging from 1 mg to 4 mg. The recommended starting dose is usually 1 mg once a day. The dose may be increased gradually, depending on the patient’s response to the drug. The maximum recommended dose is 6 mg once a day.

Administration

Glimepirida Ciclum should be taken with or immediately after food to reduce the risk of side effects. It should be taken as directed by the doctor.

Side Effects

Common side effects of Glimepirida Ciclum include nausea, dizziness, headache, diarrhea, blurred vision, and weight gain. More serious side effects such as low blood sugar levels, allergic reactions, and anemia may also occur.

Toxicity

Overdose of Glimepirida Ciclum can lead to serious side effects such as low blood sugar levels, severe allergic reactions, and anemia. If an overdose is suspected, contact a doctor or poison control center immediately.

Precaution

Patients should tell their doctor about all medications and health conditions before taking Glimepirida Ciclum. People who are allergic to sulfonamide-based drugs should not take Glimepirida Ciclum. Women who are pregnant or breastfeeding should not take Glimepirida Ciclum.

Interactions

Glimepirida Ciclum may interact with a number of drugs, including certain beta blockers, ACE inhibitors, MAO inhibitors, and diuretics. Such interactions could lead to serious side effects. Patients should tell their doctor about all medications and health conditions before taking Glimepirida Ciclum.

Disease Interaction

Patients with a history of liver or kidney disease should use Glimepirida Ciclum with caution as it may worsen their condition. Patients with certain heart conditions should not take Glimepirida Ciclum as it may increase the risk of certain heart conditions.

Drug Interaction

Glimepirida Ciclum can interact with a number of other drugs, including certain beta blockers, ACE inhibitors, MAO inhibitors, and diuretics. Such interactions could lead to serious side effects. Patients should tell their doctor about all medications and health conditions before taking Glimepirida Ciclum.

Food Interactions

Glimepirida Ciclum should be taken with or immediately after food to reduce the risk of side effects. Patients should avoid taking alcohol while taking Glimepirida Ciclum as this can increase the risk of low blood sugar levels.

Pregnancy Use

Glimepirida Ciclum should not be used in pregnant women. It may harm the fetus if used during pregnancy. Women should avoid taking Glimepirida Ciclum while pregnant or breastfeeding.

Lactation Use

It is not recommended to use Glimepirida Ciclum when breastfeeding. It may harm the infant if taken while breastfeeding.

Acute Overdose

If an overdose of Glimepirida Ciclum is suspected, contact a doctor or poison control center immediately. Symptoms of an overdose may include low blood sugar levels, severe allergic reactions, and anemia. Treatment of an overdose may involve the administration of dextrose or insulin as needed.

Contraindication

Glimepirida Ciclum is contraindicated in people who are allergic to sulfonamide-based drugs, those with liver or kidney disease, and those with certain heart conditions, as well as in women who are pregnant or breastfeeding.

Use Direction

Patients should take Glimepirida Ciclum exactly as prescribed by their doctor. The recommended starting dose is usually 1 mg once a day, taken with or immediately after food. The dose may be increased gradually, depending on the patient's response to the drug. The maximum recommended dose is 6 mg once a day.

Storage Condition

Glimepirida Ciclum should be stored at room temperature, away from direct heat and moisture. Keep in a tight, light-resistant container. Keep out of the reach of children and pets.

Volume of Distribution

The volume of distribution of Glimepirida Ciclum is 25 L.

Half Life

The half-life of Glimepirida Ciclum is 5-7 hours.

Clearance

Glimepirida Ciclum is metabolized in the liver and has a clearance of 118 ml/min.

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