Glikazid MR
Glikazid MR Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Glikazid MR is a brand name. Its generic name is Gliclazide.
Introduction
Glikazid MR (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
Glikazid MR is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
Glikazid MR works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
Glikazid MR is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
Glikazid MR is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
Glikazid MR should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
Glikazid MR can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
Glikazid MR is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
Glikazid MR can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
Glikazid MR can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
Glikazid MR may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
Glikazid MR may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
Glikazid MR can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
Glikazid MR should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
Glikazid MR should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
Glikazid MR should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
Glikazid MR should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of Glikazid MR
Some Frequently Asked Questions About Glikazid MR
What is Glikazid MR?
Glikazid MR is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does Glikazid MR work?
Glikazid MR works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of Glikazid MR?
Glikazid MR is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of Glikazid MR?
Glikazid MR may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does Glikazid MR cause hypoglycemia?
Yes, Glikazid MR can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should Glikazid MR be taken?
Glikazid MR should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for Glikazid MR to work?
Glikazid MR usually starts to work within 1-2 hours after it is taken.
Does Glikazid MR need to be taken with food?
No, Glikazid MR does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of Glikazid MR?
The recommended dose of Glikazid MR depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take Glikazid MR?
If you forget to take Glikazid MR, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking Glikazid MR?
Yes, it is recommended to avoid alcohol while taking Glikazid MR as it can increase the risk of adverse effects such as low blood sugar.
Can Glikazid MR be taken while pregnant or breastfeeding?
Glikazid MR should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking Glikazid MR?
It is important to follow a healthy and balanced diet while taking Glikazid MR. Avoid foods high in sugar, fat, and cholesterol.
Is Glikazid MR available as a generic medication?
Yes, Glikazid MR is available as a generic medication.
What other medications should not be taken with Glikazid MR?
Certain medications can interact with Glikazid MR and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take Glikazid MR with metformin?
Yes, Glikazid MR can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to Glikazid MR?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can Glikazid MR be used to treat type 1 diabetes?
No, Glikazid MR is not suitable for use in people with type 1 diabetes.
Does Glikazid MR cause weight gain?
Glikazid MR can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking Glikazid MR?
If you experience side effects while taking Glikazid MR, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking Glikazid MR?
Yes, diabetic ketoacidosis can occur while taking Glikazid MR. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should Glikazid MR be stored?
Glikazid MR should be stored at room temperature away from direct sunlight and heat. Do not keep Glikazid MR in the refrigerator or freezer.
Can I overdose on Glikazid MR?
Yes, it is possible to overdose on Glikazid MR. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking Glikazid MR?
No, it is recommended that you do not donate blood while taking Glikazid MR.
Can I take Glikazid MR if I have kidney disease?
It is recommended that you speak to your doctor before taking Glikazid MR if you have kidney disease. Your doctor may recommend a different medication.
Is Glikazid MR a blood thinner?
No, Glikazid MR is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can Glikazid MR be used to treat Type 1 diabetes?
No, Glikazid MR is not suitable for use in people with Type 1 diabetes.
Can Glikazid MR cause low blood pressure?
Yes, Glikazid MR can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take Glikazid MR while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking Glikazid MR. Certain medications can interact with Glikazid MR.
Does Glikazid MR raise cholesterol levels?
Yes, Glikazid MR can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is Glikazid MR a steroid?
No, Glikazid MR is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does Glikazid MR cause diarrhea?
Yes, Glikazid MR can cause diarrhea. If you experience diarrhea while taking Glikazid MR, speak to your doctor or pharmacist.
Can I take Glikazid MR with ibuprofen?
It is recommended that you do not take Glikazid MR with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take Glikazid MR with muscle relaxers?
It is recommended that you do not take Glikazid MR with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of Glikazid MR?
If you miss a dose of Glikazid MR, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take Glikazid MR while breastfeeding?
No, it is recommended that you do not take Glikazid MR while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take Glikazid MR while pregnant?
No, it is recommended that you do not take Glikazid MR while pregnant. Speak to your doctor before taking any medications while pregnant.
Can Glikazid MR cause headaches?
Yes, Glikazid MR can cause headaches in some people. If you experience headaches while taking Glikazid MR, speak to your doctor or pharmacist.
Can I take Glikazid MR with other diabetes medications?
Yes, Glikazid MR can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking Glikazid MR?
If you experience low blood sugar while taking Glikazid MR, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking Glikazid MR?
It is important to follow a healthy and balanced diet while taking Glikazid MR. Avoid foods high in sugar, fat, and cholesterol.
How long can I take Glikazid MR for?
The length of time that you take Glikazid MR for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is Glikazid MR a controlled substance?
No, Glikazid MR is not a controlled substance.