Gliclid
Gliclid Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Gliclid is a brand name. Its generic name is Gliclazide.
Introduction
Gliclid (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
Gliclid is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
Gliclid works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
Gliclid is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
Gliclid is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
Gliclid should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
Gliclid can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
Gliclid is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
Gliclid can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
Gliclid can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
Gliclid may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
Gliclid may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
Gliclid can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
Gliclid should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
Gliclid should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
Gliclid should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
Gliclid should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of Gliclid
Some Frequently Asked Questions About Gliclid
What is Gliclid?
Gliclid is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does Gliclid work?
Gliclid works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of Gliclid?
Gliclid is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of Gliclid?
Gliclid may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does Gliclid cause hypoglycemia?
Yes, Gliclid can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should Gliclid be taken?
Gliclid should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for Gliclid to work?
Gliclid usually starts to work within 1-2 hours after it is taken.
Does Gliclid need to be taken with food?
No, Gliclid does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of Gliclid?
The recommended dose of Gliclid depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take Gliclid?
If you forget to take Gliclid, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking Gliclid?
Yes, it is recommended to avoid alcohol while taking Gliclid as it can increase the risk of adverse effects such as low blood sugar.
Can Gliclid be taken while pregnant or breastfeeding?
Gliclid should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking Gliclid?
It is important to follow a healthy and balanced diet while taking Gliclid. Avoid foods high in sugar, fat, and cholesterol.
Is Gliclid available as a generic medication?
Yes, Gliclid is available as a generic medication.
What other medications should not be taken with Gliclid?
Certain medications can interact with Gliclid and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take Gliclid with metformin?
Yes, Gliclid can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to Gliclid?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can Gliclid be used to treat type 1 diabetes?
No, Gliclid is not suitable for use in people with type 1 diabetes.
Does Gliclid cause weight gain?
Gliclid can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking Gliclid?
If you experience side effects while taking Gliclid, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking Gliclid?
Yes, diabetic ketoacidosis can occur while taking Gliclid. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should Gliclid be stored?
Gliclid should be stored at room temperature away from direct sunlight and heat. Do not keep Gliclid in the refrigerator or freezer.
Can I overdose on Gliclid?
Yes, it is possible to overdose on Gliclid. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking Gliclid?
No, it is recommended that you do not donate blood while taking Gliclid.
Can I take Gliclid if I have kidney disease?
It is recommended that you speak to your doctor before taking Gliclid if you have kidney disease. Your doctor may recommend a different medication.
Is Gliclid a blood thinner?
No, Gliclid is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can Gliclid be used to treat Type 1 diabetes?
No, Gliclid is not suitable for use in people with Type 1 diabetes.
Can Gliclid cause low blood pressure?
Yes, Gliclid can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take Gliclid while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking Gliclid. Certain medications can interact with Gliclid.
Does Gliclid raise cholesterol levels?
Yes, Gliclid can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is Gliclid a steroid?
No, Gliclid is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does Gliclid cause diarrhea?
Yes, Gliclid can cause diarrhea. If you experience diarrhea while taking Gliclid, speak to your doctor or pharmacist.
Can I take Gliclid with ibuprofen?
It is recommended that you do not take Gliclid with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take Gliclid with muscle relaxers?
It is recommended that you do not take Gliclid with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of Gliclid?
If you miss a dose of Gliclid, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take Gliclid while breastfeeding?
No, it is recommended that you do not take Gliclid while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take Gliclid while pregnant?
No, it is recommended that you do not take Gliclid while pregnant. Speak to your doctor before taking any medications while pregnant.
Can Gliclid cause headaches?
Yes, Gliclid can cause headaches in some people. If you experience headaches while taking Gliclid, speak to your doctor or pharmacist.
Can I take Gliclid with other diabetes medications?
Yes, Gliclid can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking Gliclid?
If you experience low blood sugar while taking Gliclid, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking Gliclid?
It is important to follow a healthy and balanced diet while taking Gliclid. Avoid foods high in sugar, fat, and cholesterol.
How long can I take Gliclid for?
The length of time that you take Gliclid for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is Gliclid a controlled substance?
No, Gliclid is not a controlled substance.