Glazide
Glazide Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Glazide is a brand name. Its generic name is Gliclazide.
Introduction
Glazide (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
Glazide is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
Glazide works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
Glazide is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
Glazide is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
Glazide should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
Glazide can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
Glazide is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
Glazide can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
Glazide can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
Glazide may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
Glazide may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
Glazide can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
Glazide should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
Glazide should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
Glazide should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
Glazide should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of Glazide
Some Frequently Asked Questions About Glazide
What is Glazide?
Glazide is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does Glazide work?
Glazide works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of Glazide?
Glazide is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of Glazide?
Glazide may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does Glazide cause hypoglycemia?
Yes, Glazide can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should Glazide be taken?
Glazide should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for Glazide to work?
Glazide usually starts to work within 1-2 hours after it is taken.
Does Glazide need to be taken with food?
No, Glazide does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of Glazide?
The recommended dose of Glazide depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take Glazide?
If you forget to take Glazide, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking Glazide?
Yes, it is recommended to avoid alcohol while taking Glazide as it can increase the risk of adverse effects such as low blood sugar.
Can Glazide be taken while pregnant or breastfeeding?
Glazide should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking Glazide?
It is important to follow a healthy and balanced diet while taking Glazide. Avoid foods high in sugar, fat, and cholesterol.
Is Glazide available as a generic medication?
Yes, Glazide is available as a generic medication.
What other medications should not be taken with Glazide?
Certain medications can interact with Glazide and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take Glazide with metformin?
Yes, Glazide can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to Glazide?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can Glazide be used to treat type 1 diabetes?
No, Glazide is not suitable for use in people with type 1 diabetes.
Does Glazide cause weight gain?
Glazide can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking Glazide?
If you experience side effects while taking Glazide, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking Glazide?
Yes, diabetic ketoacidosis can occur while taking Glazide. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should Glazide be stored?
Glazide should be stored at room temperature away from direct sunlight and heat. Do not keep Glazide in the refrigerator or freezer.
Can I overdose on Glazide?
Yes, it is possible to overdose on Glazide. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking Glazide?
No, it is recommended that you do not donate blood while taking Glazide.
Can I take Glazide if I have kidney disease?
It is recommended that you speak to your doctor before taking Glazide if you have kidney disease. Your doctor may recommend a different medication.
Is Glazide a blood thinner?
No, Glazide is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can Glazide be used to treat Type 1 diabetes?
No, Glazide is not suitable for use in people with Type 1 diabetes.
Can Glazide cause low blood pressure?
Yes, Glazide can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take Glazide while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking Glazide. Certain medications can interact with Glazide.
Does Glazide raise cholesterol levels?
Yes, Glazide can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is Glazide a steroid?
No, Glazide is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does Glazide cause diarrhea?
Yes, Glazide can cause diarrhea. If you experience diarrhea while taking Glazide, speak to your doctor or pharmacist.
Can I take Glazide with ibuprofen?
It is recommended that you do not take Glazide with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take Glazide with muscle relaxers?
It is recommended that you do not take Glazide with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of Glazide?
If you miss a dose of Glazide, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take Glazide while breastfeeding?
No, it is recommended that you do not take Glazide while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take Glazide while pregnant?
No, it is recommended that you do not take Glazide while pregnant. Speak to your doctor before taking any medications while pregnant.
Can Glazide cause headaches?
Yes, Glazide can cause headaches in some people. If you experience headaches while taking Glazide, speak to your doctor or pharmacist.
Can I take Glazide with other diabetes medications?
Yes, Glazide can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking Glazide?
If you experience low blood sugar while taking Glazide, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking Glazide?
It is important to follow a healthy and balanced diet while taking Glazide. Avoid foods high in sugar, fat, and cholesterol.
How long can I take Glazide for?
The length of time that you take Glazide for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is Glazide a controlled substance?
No, Glazide is not a controlled substance.