GL-80
GL-80 Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? GL-80 is a brand name. Its generic name is Gliclazide.
Introduction
GL-80 (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
GL-80 is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
GL-80 works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
GL-80 is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
GL-80 is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
GL-80 should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
GL-80 can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
GL-80 is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
GL-80 can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
GL-80 can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
GL-80 may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
GL-80 may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
GL-80 can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
GL-80 should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
GL-80 should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
GL-80 should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
GL-80 should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of GL-80
Some Frequently Asked Questions About GL-80
What is GL-80?
GL-80 is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does GL-80 work?
GL-80 works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of GL-80?
GL-80 is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of GL-80?
GL-80 may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does GL-80 cause hypoglycemia?
Yes, GL-80 can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should GL-80 be taken?
GL-80 should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for GL-80 to work?
GL-80 usually starts to work within 1-2 hours after it is taken.
Does GL-80 need to be taken with food?
No, GL-80 does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of GL-80?
The recommended dose of GL-80 depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take GL-80?
If you forget to take GL-80, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking GL-80?
Yes, it is recommended to avoid alcohol while taking GL-80 as it can increase the risk of adverse effects such as low blood sugar.
Can GL-80 be taken while pregnant or breastfeeding?
GL-80 should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking GL-80?
It is important to follow a healthy and balanced diet while taking GL-80. Avoid foods high in sugar, fat, and cholesterol.
Is GL-80 available as a generic medication?
Yes, GL-80 is available as a generic medication.
What other medications should not be taken with GL-80?
Certain medications can interact with GL-80 and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take GL-80 with metformin?
Yes, GL-80 can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to GL-80?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can GL-80 be used to treat type 1 diabetes?
No, GL-80 is not suitable for use in people with type 1 diabetes.
Does GL-80 cause weight gain?
GL-80 can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking GL-80?
If you experience side effects while taking GL-80, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking GL-80?
Yes, diabetic ketoacidosis can occur while taking GL-80. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should GL-80 be stored?
GL-80 should be stored at room temperature away from direct sunlight and heat. Do not keep GL-80 in the refrigerator or freezer.
Can I overdose on GL-80?
Yes, it is possible to overdose on GL-80. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking GL-80?
No, it is recommended that you do not donate blood while taking GL-80.
Can I take GL-80 if I have kidney disease?
It is recommended that you speak to your doctor before taking GL-80 if you have kidney disease. Your doctor may recommend a different medication.
Is GL-80 a blood thinner?
No, GL-80 is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can GL-80 be used to treat Type 1 diabetes?
No, GL-80 is not suitable for use in people with Type 1 diabetes.
Can GL-80 cause low blood pressure?
Yes, GL-80 can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take GL-80 while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking GL-80. Certain medications can interact with GL-80.
Does GL-80 raise cholesterol levels?
Yes, GL-80 can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is GL-80 a steroid?
No, GL-80 is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does GL-80 cause diarrhea?
Yes, GL-80 can cause diarrhea. If you experience diarrhea while taking GL-80, speak to your doctor or pharmacist.
Can I take GL-80 with ibuprofen?
It is recommended that you do not take GL-80 with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take GL-80 with muscle relaxers?
It is recommended that you do not take GL-80 with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of GL-80?
If you miss a dose of GL-80, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take GL-80 while breastfeeding?
No, it is recommended that you do not take GL-80 while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take GL-80 while pregnant?
No, it is recommended that you do not take GL-80 while pregnant. Speak to your doctor before taking any medications while pregnant.
Can GL-80 cause headaches?
Yes, GL-80 can cause headaches in some people. If you experience headaches while taking GL-80, speak to your doctor or pharmacist.
Can I take GL-80 with other diabetes medications?
Yes, GL-80 can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking GL-80?
If you experience low blood sugar while taking GL-80, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking GL-80?
It is important to follow a healthy and balanced diet while taking GL-80. Avoid foods high in sugar, fat, and cholesterol.
How long can I take GL-80 for?
The length of time that you take GL-80 for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is GL-80 a controlled substance?
No, GL-80 is not a controlled substance.