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গেমসিটাবাইন একভিডা (আইভি ইনজেকশন)

By BioRx

Weight: 20 mg/ml

Unit Price: 1.4

Last Updated: 2019-11-05 09:25:23

গেমসিটাবাইন একভিডা আইভি ইনজেকশন এর কাজ

Ovarian Cancer: Gemcitabine in combination with carboplatin is indicated for the treatment of patients with advanced ovarian cancer that has relapsed at least 6 months after completion of platinum-based therapy.

Breast Cancer: Gemcitabine in combination with paclitaxel is indicated for the first-line treatment of patients with metastatic breast cancer after failure of prior anthracycline-containing adjuvant chemotherapy, unless anthracyclines were clinically contraindicated.

Non-Small Cell Lung Cancer: Gemcitabine is indicated in combination with cisplatin for the first-line treatment of patients with inoperable, locally advanced (Stage IIIA or IIIB), or metastatic (Stage IV) non-small cell lung cancer.

Pancreatic Cancer: Gemcitabine is indicated as first-line treatment for patients with locally advanced (nonresectable Stage II or Stage III) or metastatic (Stage IV) adenocarcinoma of the pancreas. Gemcitabine is indicated for patients previously treated with 5-FU.

গেমসিটাবাইন একভিডা জেনারিক

Gemcitabine

গেমসিটাবাইন একভিডা পরিচিতি

Gemcitabine is a synthetic pyrimidine nucleoside and cytarabine analogue which is metabolised intracellularly to active diphosphate and triphosphate nucleosides. It inhibits DNA synthesis by inhibiting DNA polymerase and ribonucleotide reductase. It also induces apoptosis and is primarily active against cells in the S-phase, but may also arrest cells at the G1-S border.

গেমসিটাবাইন একভিডা চিকিত্সাবিদ্যাগত শ্রেণী

Cytotoxic Chemotherapy

গেমসিটাবাইন একভিডা আইভি ইনজেকশন খাওয়ার নিয়ম

Intravenous (Adult)-

  • Advanced non-small cell lung cancer: 1000 mg/m2 on days 1, 8 and 15 of each 28-day cycle; or 1250 mg/m2 on days 1 and 8 of each 21-day cycle.
  • Pancreatic carcinoma: 1000 mg/m2 once wkly for up to 7 wk followed by 1 wk of rest. Continue thereafter with once wkly infusions for 3 consecutive wk out of 4.
  • Ovarian carcinoma: To be given before carboplatin: 1000 mg/m2 on days 1 and 8 of each 21-day cycle.
  • Breast cancer: Usually in combination with a taxane such as paclitaxel: 1250 mg/m2 on days 1 and 8 of each 21-day cycle.
  • Bladder cancer: To be given before cisplatin. 1000 mg/m2 on days 1, 8 and 15 of each 28-day cycle.

গেমসিটাবাইন একভিডা এর প্রয়োগ-পদ্ধতি

গেমসিটাবাইন একভিডা আইভি ইনজেকশন এর পার্শ্বপ্রতিক্রিয়া

Bone marrow suppression as manifested by leukopenia, thrombocytopenia, anaemia and myelosuppression. Mild GI effects; rashes; renal impairment, pulmonary toxicity, influenza-like symptoms; interstitial pneumonia, pulmonary oedema. Proteinuria, haematuria and haemolytic uraemic syndrome. Elevation of serum transaminase.

গেমসিটাবাইন একভিডা ব্যবহারে সতর্কতা

Children, hepatic and renal impairment. May impair ability to drive or operate machinery. Discontinue on 1st sign of microangiopathic haemolytic anaemia. Prolonged infusion time (>60 minutes) and more frequent than wkly dosing may increase toxicity. Monitor CBC before every dose. Increased risk of haemolytic uraemic syndrome and/or thrombocytcpenic purpura which may lead to irreversible renal failure.

গেমসিটাবাইন একভিডা এর প্রতিক্রিয়া

May increase the anticoagulant effect of warfarin when used together.

গেমসিটাবাইন একভিডা গর্ভকালীন কিংবা দুগ্ধদানকালীন অবস্থায় ব্যবহার

Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

গেমসিটাবাইন একভিডা মাত্রাতিরিক্ত সেবনের প্রতিক্রিয়া

 

গেমসিটাবাইন একভিডা এর প্রতিনির্দেশনা

Concurrent radical radiotherapy; pregnancy, lactation; hypersensitivity

গেমসিটাবাইন একভিডা এর ব্যবহারবিধি

 

গেমসিটাবাইন একভিডা সংরক্ষণ

Store at 25° C.

গেমসিটাবাইন একভিডা এর বিশেষ সতর্কতা

 

গেমসিটাবাইন একভিডা এর অন্যান্য ঔষধের সাথে প্রতিক্রিয়া