ফ্রিনস এ আছে Pseudoephedrine + Triprolidine। ফ্রিনস এর কাজঃ
This combination medication is used to temporarily relieve symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis). Pseudoephedrine (antihistamines) help relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Triprolidine (decongestants) help to relieve stuffy nose and ear congestion symptoms
|Frenos Tablet 2.5 mg+60 mg in bangla|
|জেনেরিকঃ||Pseudoephedrine + Triprolidine|
|পরিমাপঃ||2.5 mg+60 mg|
|চিকিৎসাগত শ্রেণিঃ||Combined cough suppressants|
|উৎপাদনকারীঃ||Opsonin Pharma Ltd|
|সর্বশেষ সম্পাদনাঃ||2020-11-20 18:15:00|
Pseudoephedrine is a decongestant as well as a bronchodilator for the upper respiratory tract, which gives symptomatic relief of nasal congestion. Pseudoephedrine is both an α-and β-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of α-adrenergic receptors of the respiratory mucosa. It also directly stimulates β-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility.
Like ephedrine, pseudoephedrine releasing norepinephrine from its storage sites, an indirect effect. This is its main and direct mechanism of action. The displaced noradrenaline is released into the neuronal synapse where it is free to activate the postsynaptic adrenergic receptors.
Triprolidine binds to the histamine H1 receptor. This block the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.
ফ্রিনস এ আছে Pseudoephedrine + Triprolidine 2.5 mg+60 mg। ফ্রিনস খাওয়ার নিয়ম নিম্নরূপঃ
Adult: 1 tablet 4-6 hrly, up to 4 times a day.
Child >12 year: 1 tablet 4-6 hrly, up to 4 times a day.
Drowsiness, dizziness, dry mouth/nose/throat, headache, upset stomach, constipation, or trouble sleeping may occur.
Severe hepatic impairment. Moderate to severe renal impairment. DM, hyperthyroidism, increased intraocular pressure, prostatic hypertrophy, hypertension, heart disease. May affect ability to drive or operate machinery. Pregnancy and lactation.
Increased BP with other sympathomimetic agents (e.g. decongestants, TCA, appetite suppressants). Reduced hypotensive effects of methyldopa, α- and β-adrenergic blockers. Increased side effects (e.g. somnolence, agitation) with atomoxetine.
Pregnancy Category- C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Concurrent use or within 2 wk of stopping MAOIs. Severe hypertension or coronary artery disease.
Symptoms: Drowsiness, lethargy, dizziness, ataxia, weakness, difficulty passing urine, dry skin, tachycardia, hypertension, high fever, hyperactivity, irritability, seizures and respiratory depression.
Management: Gastric lavage may be performed up to 3 hr after overdose. Treatment is supportive and symptomatic. Acid diuresis or dialysis may be helpful in pseudoephedrine elimination.
Tablet: Do not store above 25° C.
Syrup: Do not store above 25° C. Diluted syrup can be stored up to 4 wk at 25° C.
ফ্রিনস ট্যাবলেট এর দাম 4.91