Frefast
Frefast Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Frefast is a brand name. Its generic name is Methyl Salicylate + Menthol + Camphor.
Introduction
Methyl salicylate, menthol, and camphor are topical analgesics commonly found in many over-the-counter ointments and other medications. The combination of these three ingredients provides relief from pain, itching, and other ailments. When applied to the skin, the menthol and camphor provide a cooling sensation, while the methyl salicylate acts as a topical analgesic to reduce pain.Uses
Methyl salicylate, menthol, and camphor are used primarily to provide relief from skin irritations and pain, including itching, rashes, muscle and joint aches, and sprains, as well as sunburns. They can also be used to temporarily relieve minor aches and pains of the muscles and joints, and chest congestion.Mechanism of Action
Methyl salicylate, menthol, and camphor work together to provide relief from irritations and pain. Methyl salicylate acts as a topical analgesic, providing relief from pain and inflammation. Menthol and camphor are cooling agents that provide a pleasant sensation when applied to the skin. In addition, menthol has anti-pruritic properties, which help to reduce itching.How Long Does it Take to Work?
The combination of methyl salicylate, menthol, and camphor typically takes effect upon first application. However, the effects may vary from person to person, and may last for around an hour or two.Absorption
Methyl salicylate, menthol, and camphor are absorbed through the skin and enter the bloodstream, where they are rapidly distributed throughout the body.Route of Elimination
Methyl salicylate, menthol, and camphor are broken down and eliminated from the body through the kidneys.Dosage
The typical dosage of methyl salicylate, menthol, and camphor is 2.5%, 0.5%, and 3.3% by weight respectively. The dosage may vary depending on the patient’s condition and should only be administered under medical supervision.Administration
Methyl salicylate, menthol, and camphor can be applied topically to the affected area(s) up to four times a day, or as directed by a medical professional. It is important to apply an even coating of the medication and not to exceed the recommended dosage.Side Effects
Possible side effects of methyl salicylate, menthol, and camphor include skin irritation, redness, burning, and stinging. In some cases, the combination of these substances may also cause an allergic reaction. If any of these side effects occur, contact a physician promptly.Toxicity
Methyl salicylate, menthol, and camphor can be toxic if taken in large quantities or if the prescribed dosage is exceeded. If any of these substances are ingested, seek medical attention immediately.Precaution
Methyl salicylate, menthol, and camphor should be used with caution. Do not use more than the recommended dosage or apply to broken or irritated skin. Avoid contact with eyes, mouth, or nasal cavity. Do not use on children under 2 years old without a doctor's consent.Interactions
Methyl salicylate, menthol, and camphor may interact with other medications or herbal supplements. Tell your doctor about any prescription or over-the-counter medications you are taking, as well as any herbal supplements.Disease Interactions
Methyl salicylate, menthol, and camphor may interact with certain medical conditions. Tell your doctor if you have a kidney or liver disorder, asthma, diabetes, or any other medical conditions.Drug Interactions
Methyl salicylate, menthol, and camphor may interact with certain drugs. Tell your doctor if you are taking any prescription medications, especially aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), or blood-thinning drugs.Food Interactions
Methyl salicylate, menthol, and camphor may interact with certain foods. Avoid eating excessive amounts of grapefruit or interacting foods, as this can increase the effects and side effects of these medicines.Pregnancy Use
Methyl salicylate, menthol, and camphor should be used with caution during pregnancy. These substances may pass through the placenta and into the unborn child. Talk to your doctor before using this product, as it may harm an unborn baby.Lactation Use
Methyl salicylate, menthol, and camphor should be used with caution while breastfeeding. These substances may pass into the breast milk and may cause harm to an infant. Talk to your doctor before using this product, as it may harm an infant.Acute Overdose
An acute overdose of methyl salicylate, menthol, and camphor may cause serious side effects, including nausea, vomiting, headache, dizziness, irregular heartbeat, confusion, agitation, seizures, or loss of consciousness. If you suspect an overdose, seek medical attention immediately.Contraindication
Methyl salicylate, menthol, and camphor should not be used by those who are allergic to any of the ingredients. It should not be used on broken or irritated skin. It should also not be used by people taking aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), or blood-thinning drugs unless otherwise directed by a medical professional.Use Direction
Methyl salicylate, menthol, and camphor should be applied topically to the affected area up to four times a day, or as directed by a medical professional. Do not exceed the recommended dosage.Storage Condition
Methyl salicylate, menthol, and camphor should be stored at room temperature, away from direct sunlight and heat. Keep out of reach of children.Volume of Distribution
Methyl salicylate, menthol, and camphor have a relatively low volume of distribution, meaning they are quickly and easily absorbed through the skin and into the bloodstream.Half Life
Methyl salicylate, menthol, and camphor are quickly eliminated from the body. They have an estimated half-life of 1.76 hours.Clearance
Methyl salicylate, menthol, and camphor are eliminated from the body through the kidneys. The clearance rate is estimated to be 9.43 ml/min/1.73 m2.Here you find in details version of Frefast