Fixal Plus

Fixal Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Fixal Plus is a brand name. Its generic name is Fexofenadine + Pseudoephedrine.

Introduction

Fixal Plus is a combination medication used to temporarily relieve the symptoms of seasonal allergies such as sneezing, watery eyes, and runny nose. It is an antihistamine (fexofenadine) and decongestant (pseudoephedrine) combination drug.

Uses For

Fixal Plus is indicated for treating seasonal allergy symptoms, such as sneezing, nasal stuffiness and itchiness. It is useful for treating congestion due to these allergies.

Mechanism of Action

Fexofenadine is an orally active antihistamine that blocks the release of histamine in the body as a result of allergic reactions. Histamine is a substance that causes allergic symptoms. Pseudoephedrine is an orally active decongestant that works by constricting the blood vessels in the nose, thereby reducing nasal congestion.

How Long Does It Take to Work

Relief of symptoms can be noticed within 1 hour from the intake of Fixal Plus. However, its effect can last up to 12 hours.

Absorption

Fixal Plus is rapidly and completely absorbed after oral administration with peak plasma concentrations occurring in 1-3 hours.

Route Of Elimination

Fixal Plus is excreted mainly in the urine as unchanged drug and metabolites.

Dosage

The dosage of Fixal Plus should be taken exactly as prescribed by the physician. Usually, the recommended doses of Fixal Plus capsules are one capsule twice a day. The maximum dose is two 120 mg/60 mg oral capsules twice a day. It may be taken with or without food.

Administration

Fixal Plus tablets should be taken by mouth, usually twice daily. It can be taken with or without food.

Side Effects

Common side effects of Fixal Plus include drowsiness, dizziness, headache, nausea, dry mouth, upset stomach, and diarrhea.

Toxicity

The adverse effects of Fixal Plus can become serious if taken in excessive doses. Common toxic symptoms include racing heartbeat, nervousness, tremors, high blood pressure, chest pain, and tingling in the extremities.

Precaution

Patients with high blood pressure, heart diseases, glaucoma, diabetes, hyperthyroidism, kidney disease, or enlarged prostate should use Fixal Plus cautiously.
Patients who are currently taking monoamine oxidase inhibitors (MAOIs) or who have taken them within the past two weeks should not take Fixal Plus.
Pregnant women and breastfeeding women should consult their doctor before taking Fixal Plus.
Patients who are taking other medications should consult their doctor before taking Fixal Plus.
Patients should not take alcohol while taking Fixal Plus.

Interaction

Fixal Plus may interact with certain medications such as alcohol, warfarin, and other antihistamines. Therefore, patients should consult their doctor before taking other medications while on Fixal Plus.

Disease Interaction

Fixal Plus should be used with caution among elderly patients and those with hepatic or renal impairment.

Drug Interaction

Fixal Plus may interact with other drugs such as antidepressants, benzodiazepines, oral contraceptives, and antifungals. Therefore, it is important to inform the doctor of any medications being taken before taking Fixal Plus.

Food Interactions

Fixal Plus may interact with certain foods, such as food containing a large amount of calcium or aluminum. Therefore, patients should consult their doctor before taking this medication with food.

Pregnancy Use

Fixal Plus should be avoided during pregnancy unless absolutely necessary. Women should consult their doctor before taking this medication during pregnancy.

Lactation Use

Fixal Plus should be avoided during lactation unless medically necessary. Women should consult their doctor before taking Fixal Plus while breastfeeding.

Acute Overdose

The signs of an acute overdose of Fixal Plus include restlessness, rapid heartbeat, excessive sweating, nausea, vomiting, abdominal pain, blurred vision, confusion, and dizziness.

Contraindication

Fixal Plus should not be taken in the presence of any known hypersensitivity to any of the ingredients.

Use Direction

Fixal Plus should be taken exactly as prescribed by the doctor. It should not be taken in larger or smaller amounts than recommended by the doctor.

Storage Condition

Fixal Plus should be stored at a temperature between 20°C and 25°C. Keep away from direct sunlight and moisture.

Volume of Distribution

The Volume of Distribution of Fixal Plus is reported to be 1.6 L/Kg.

Half Life

The elimination half-life of Fexofenadine is reported to be 18 hours. The elimination half-life of Pseudoephedrine is reported to be 9.8 hours.

Clearance

The clearance of Fexofenadine is reported to be 17.2 ± 4.3 mL/min/kg. The clearance of Pseudoephedrine is reported to be 24.4 ± 10.3 mL/min/kg.

Here you find in details version of Fixal Plus

Some Frequently Asked Questions About Fixal Plus

What is Fixal Plus?

Fixal Plus is a combination medicine that can be used to treat both nasal congestion and allergies. This medication is a combination of two drugs, a histamine blocker (fexofenadine) and a decongestant (pseudoephedrine). It works by blocking the effects of histamine, which is a natural substance that causes an allergic reaction, as well as reducing nasal congestion.

What is Fexofenadine?

Fexofenadine is an antihistamine drug that is used to treat allergic symptoms such as itching, sneezing, runny nose, watery eyes, and hives. It works by blocking the effects of histamine, which is a natural substance that causes an allergic reaction.

What is Pseudoephedrine?

Pseudoephedrine is a decongestant drug that is used to treat nasal congestion. It works by narrowing the small blood vessels in the nose, which helps to reduce congestion and stuffiness.

What are the uses of Fixal Plus?

Fixal Plus is used to relieve nasal congestion and allergic symptoms caused by hay fever or other allergies. It can also be used to relieve symptoms associated with the common cold.

What are the side effects of Fixal Plus?

Common side effects of Fixal Plus include headache, drowsiness, nausea, dry mouth, and throat irritation. More serious side effects may include rapid heartbeat, dizziness, difficulty breathing, and jitteriness.

Who should not take Fixal Plus?

Fixal Plus should not be taken by people with certain medical conditions, such as high blood pressure, adrenal gland problems, severe liver or kidney disease, narrow-angle glaucoma, or difficulty urinating. It should also not be taken by people who are taking certain other medications, such as MAO inhibitors or people who are sensitive to any of the ingredients in the medication.

What is the recommended dosage for Fixal Plus?

The recommended dosage for Fixal Plus depends on the person's age and weight. It is important to follow the instructions of your doctor or pharmacist for the correct dosage. Overdose of this medication can be dangerous and it is important to follow the directions carefully.

What should I do if I missed a dose of Fixal Plus?

If you forget to take a dose of Fixal Plus, take it as soon as you can. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed dose.

Can I take Fixal Plus while pregnant?

Fixal Plus should not be taken during pregnancy unless it is absolutely necessary. It's important to talk to your doctor before taking this medication if you are pregnant as there may be risks associated with taking it during pregnancy.

Can I take Fixal Plus while breastfeeding?

Fixal Plus should not be taken while breastfeeding because it can pass into breast milk and may be harmful to the infant. It's important to talk to your doctor before taking this medication if you are breastfeeding as there may be risks associated with taking it while breastfeeding.

Can Fixal Plus be used for children?

Fixal Plus is generally not recommended for use in children younger than 12 years of age unless it is absolutely necessary. Children younger than 12 years of age should not take more than one tablet per day. It is important to talk to your doctor before giving this medication to a child.

Can Fixal Plus interact with other medications?

Yes, Fixal Plus can interact with other medications. It is important to tell your doctor about all other medications you are taking, including non-prescription medications, vitamins, and herbal supplements. This will help to prevent any drug interactions that may occur.

What should I do if I have an allergic reaction to Fixal Plus?

If you have an allergic reaction to Fixal Plus, stop taking the medication immediately and seek medical attention. Common signs of an allergic reaction include hives, difficulty breathing, swelling of the lips, tongue or throat, and chest pain.

Are there any diet restrictions while taking Fixal Plus?

No, there are no diet restrictions while taking Fixal Plus. However, it is important to stay hydrated and maintain a healthy diet in general.

What is the difference between Fixal Plus and Fexofenadine?

The main difference between Fixal Plus and Fexofenadine is that Fixal Plus contains a decongestant (pseudoephedrine) that can provide added relief from nasal congestion, while Fexofenadine does not have this added relief.

What should I avoid while taking Fixal Plus?

It is important to avoid driving or operating heavy machinery while taking Fixal Plus, as this medication can cause drowsiness and dizziness. It is also important to avoid drinking alcohol and using other medications that can interact with Fixal Plus, such as MAO inhibitors.

Should I take Fixal Plus with food?

Fixal Plus can be taken with or without food. However, it may be better to take it with food to reduce the risk of stomach upset or nausea.

How long does it take for Fixal Plus to start working?

It usually takes about 30 minutes for Fixal Plus to start working. However, it can take up to 2 hours for the full effects of this medication to be felt.

What should I do if I experience side effects while taking Fixal Plus?

If you experience any side effects while taking Fixal Plus, it is important to contact your doctor or pharmacist. They will be able to advise you on the best course of action to manage the side effects.

I have high blood pressure. Can I take Fixal Plus?

Fixal Plus should not be taken by people with high blood pressure, as this medication can increase blood pressure. It's important to talk to your doctor before taking this medication if you have high blood pressure as there may be other risks associated with taking it.

Does Fixal Plus cause sedation?

Fixal Plus may cause drowsiness or sedation in some people. It is important to avoid driving or operating heavy machinery while taking this medication until you know how it affects you.

Does Fixal Plus interact with other herbal supplements?

Yes, Fixal Plus can interact with other herbal supplements. It is important to tell your doctor about all other medications you are taking, including non-prescription medications, vitamins, and herbal supplements. This will help to prevent any drug interactions that may occur.

Does Fixal Plus cause weight gain?

Fixal Plus does not cause weight gain. However, it can cause an increase in appetite, which can lead to weight gain if not managed properly.

What is the lowest dose of Fixal Plus available?

The lowest dose of Fixal Plus available is 1 tablet, which contains 120 mg of Fexofenadine and 60 mg of Pseudoephedrine.

Does Fixal Plus come in liquid form?

No, Fixal Plus is only available in tablet form.

Can Fixal Plus be taken with antihistamines?

No, Fixal Plus should not be taken with antihistamines as this can increase the risk of side effects. It is important to talk to your doctor before taking this medication if you are taking any other medications.

Does Fixal Plus cause dry mouth?

Yes, Fixal Plus may cause dry mouth. It is important to take sips of water or chew sugar-free gum to help reduce the dryness. It is also important to avoid drinking alcohol, as this can worsen the dryness.

Does Fixal Plus interact with other medications?

Can Fixal Plus be used to treat a cold?

Yes, Fixal Plus can be used to treat a cold. It is a combination of two drugs, a histamine blocker (fexofenadine) and a decongestant (pseudoephedrine) which can work together to reduce the symptoms of a cold.

What is the difference between Fixal Plus and Benadryl?

The main difference between Fixal Plus and Benadryl is that Fixal Plus contains both an antihistamine (fexofenadine) and a decongestant (pseudoephedrine), while Benadryl only contains an antihistamine.

Can I take Fixal Plus at the same time as ibuprofen?

It is generally not recommended to take Fixal Plus at the same time as ibuprofen, as this can increase the risk of side effects. It is important to talk to your doctor or pharmacist before taking these medications together.

What does Fixal Plus do?

Can I take Fixal Plus while taking other medications?

Yes, Fexofenadine

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