Evran

Evran Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Evran is a brand name. Its generic name is Ranitidine.

Introduction

Evran is a histamine-2(H2)-blocker used to treat and prevent stomach and duodenal ulcers, and to treat other stomach and gastrointestinal conditions. It is an over-the-counter drug, available both as a prescription and non-prescription medication.

Uses

Evran is used to treat gastrointestinal disorders such as gastroesophageal reflux disease (GERD), ulcers, and other conditions involving excessive stomach acid. It can also be used to prevent stress ulcers, to treat heartburn, and to reduce the occurrence of stomach or duodenal ulcers

Mechanism of Action

Evran works by reducing the amount of acid produced by the stomach, therefore reducing the symptoms of heartburn and other gastrointestinal conditions. It does this by blocking histamine-2, which reduces the amount of acid production in the stomach in response to food.

How Long Does it Take to Work?

Evran begins to reduce stomach acid production and improve symptoms within a few hours or days after the first dose. The maximum benefit is usually reached within 4 weeks.

Absorption

Evran is well absorbed in the stomach and intestine. It has an oral absorption rate of 65-80%.

Route of Elimination

Evran is eliminated by the kidneys through urine via glomerular filtration and tubular secretion. Its elimination half-life is 1-2 hours.

Dosage

Evran is available in tablets, capsules, and suspension forms. The dosage forms and strengths are as follows:

  • Tablet: 75 mg, 150 mg, and 300 mg
  • Capsules: 75 mg and 150 mg
  • Suspension: 10 mg/mL

The usual adult dose for treatment of active duodenal ulcers is 150 mg to 300 mg twice daily. For maintenance of healing of duodenal ulcers, 150 mg once daily is recommended.

For treatment of esophageal reflux, the usual dose is 150 to 300 mg twice daily. For maintenance of healing of esophageal lesions, the recommended dose is 150 mg once daily.

For treatment of conditions involving excessive stomach acid, the recommended dose is 150 to 300 mg twice daily.

Administration

Evran can be taken with or without food. It should be taken with a full glass of water to ensure that it is completely absorbed. It is important to consume the full amount of water that is recommended for each dose.

Side Effects

Common side effects of ranitidine include headache, diarrhea, constipation, nausea, rash, dizziness, and abdominal pain. Less common side effects may include muscle pain, joint pain, fever, mental confusion, and depression.

Toxicity

Evran has a low toxicity and is generally well tolerated. Large doses may cause hypotension and can be fatal in cases of overdose.

Precautions

Evran should be used with caution in people with kidney or liver disease, and those with a history of drug allergies.

Interactions

Evran may interact with other medications including antacids, drugs used to treat heartburn, anti-seizure medications, certain antibiotics, and theophyllines.

Disease Interactions

Evran should not be used in people with porphyria, a rare metabolic disorder. It should also be used with caution in people with severe kidney disease.

Drug Interactions

Evran can interact with certain medications such as antacids, drugs used to treat heartburn, anti-seizure medications, certain antibiotics, and theophyllines. Be sure to discuss all medications you are taking with your healthcare provider before taking ranitidine.

Food Interactions

Evran may interact with food. Consuming alcohol while taking ranitidine may increase the risk of side effects such as headache, dizziness, and drowsiness.

Pregnancy Use

Evran should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Be sure to discuss the use of ranitidine with your healthcare provider before using it during pregnancy.

Lactation Use

Evran is excreted in breast milk and may affect a nursing baby. Therefore, it should be used with caution in breastfeeding women.

Acute Overdose

If an overdose of Evran occurs, seek medical attention immediately. Symptoms of overdose may include low blood pressure, dizziness, and unusual sleepiness.

Contraindication

Evran is contraindicated in people who are allergic to the active ingredient in the drug.

Use Direction

Evran should be taken as directed by your healthcare provider. The usual adult dose for treatment of active duodenal ulcers is 150 mg to 300 mg twice daily. For maintenance of healing of duodenal ulcers, 150 mg once daily is recommended.

Storage Condition

Evran should be stored at room temperature, away from heat and moisture. Keep out of reach of children.

Volume of Distribution

The apparent volume of distribution for Evran is 5L/kg.

Half Life

The half-life of Evran is 1-2 hours.

Clearance

The clearance for Evran is 10 mL/min/kg.

Here you find in details version of Evran

Some Frequently Asked Questions About Evran

.

What is Evran?

Evran is an over-the-counter and prescription histamine-2 blocker or H2 blocker used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison Syndrome (ZES) and other conditions caused by too much acid in the stomach.

How does Evran work?

Evran works by inhibiting the production of acid in the stomach, thus reducing the symptoms of acid reflux. It can also protect the lining of the stomach from damage due to the excess stomach acid.

What is the brand name of Evran?

The brand name of Evran is Zantac.

What is the dosage of Evran?

The dosage of Evran depends on the medical condition and age of the patient; however, the usual dosage for adults in the treatment of acid reflux is 150 mg twice a day.

What are the side effects of Evran?

The most common side effects of Evran include headache, dizziness, nausea, and diarrhea. Other less common side effects include constipation, stomach pain, and rash.

Does Evran interact with other medications?

Yes, Evran can interact with other medications such as anticoagulants, sulfonylureas, and NSAIDs. Talk to your doctor or pharmacist before taking any other medication while taking Evran.

What is the difference between Evran and Famotidine?

Evran and Famotidine are both H2 blockers used for treating acid reflux and GERD. The main difference between them is that Evran is more effective for treating Zollinger-Ellison Syndrome. In terms of side effects, Evran may cause headaches and dizziness, while Famotidine may cause diarrhea.

Can I take Evran while pregnant/breastfeeding?

It is not recommended to take Evran while pregnant or breastfeeding as it may be harmful to the fetus or infant. Talk to your doctor before taking Evran during pregnancy or while breastfeeding.

How long does it take for Evran to work?

Evran usually begins to work within an hour of taking it and continues to work for up to 12 hours.

Can I take Tylenol (acetaminophen) and Evran together?

Yes, it is safe to take Tylenol (acetaminophen) and Evran together.

Is Evran a laxative?

No, Evran is not a laxative.

How should I take Evran?

Evran should be taken with or without food as prescribed by a doctor. It is important to take Evran exactly as prescribed and not to take more or less than recommended.

Can I take Evran long-term?

Evran can be taken long-term if it is necessary and advised by your doctor. It may be necessary to take Evran long-term to treat certain conditions, such as Zollinger-Ellison Syndrome.

What foods should I avoid while taking Evran?

It is recommended to avoid eating any food that increases the production of acid in the stomach, such as alcohol, caffeine, spicy foods, and citrus fruits while taking Evran.

Can Evran cause weight gain?

No, there is no evidence to suggest that Evran is linked to weight gain.

Can I take Omeprazole and Evran together?

No, it is not recommended to take Omeprazole and Evran together as they are both H2 blockers that work by suppressing acid production in the stomach.

Can I take vitamin C while taking Evran?

Yes, it is safe to take vitamin C while taking Evran.

Does Evran raise blood pressure?

No, there is no evidence to suggest that Evran is linked to increased blood pressure.

Can I take Evran if I have diabetes?

Yes, it is safe to take Evran if you have diabetes.

Can I take ibuprofen and Evran together?

Yes, it is safe to take ibuprofen and Evran together.

Can I take aspirin and Evran together?

Yes, it is safe to take aspirin and Evran together.

Does Evran cause constipation?

Yes, Evran can cause constipation in some people. If you experience constipation while taking Evran, it is important to contact your doctor.

Can I take Pepto-Bismol and Evran together?

No, it is not recommended to take Pepto-Bismol and Evran together as they both contain bismuth, which can have adverse effects when taken together.

What is the best time of day to take Evran?

The best time of day to take Evran depends on the dosage prescribed by your doctor. However, as a general rule, it is best to take the medication after meals or before bedtime.

Can I take Axid and Evran together?

No, it is not recommended to take Axid and Evran together as they both contain similar active ingredients and can lead to an overdose.

Can Evran cause liver damage?

Evran is not known to cause liver damage; however, if you notice any signs or symptoms of liver damage, it is important to contact your doctor immediately.

Can I take synthroid and Evran together?

Yes, it is safe to take synthroid and Evran together.

Does Evran cause weight loss?

No, there is no evidence to suggest that Evran is linked to weight loss.

Can Evran increase anxiety?

Yes, Evran can increase anxiety in some people. If you experience anxiety while taking Evran, it is important to contact your doctor.

Can Evran cause diarrhea?

Yes, Evran can cause diarrhea in some people. If you experience diarrhea while taking Evran, it is important to contact your doctor.

Can I take Prilosec and Evran together?

No, it is not recommended to take Prilosec and Evran together as they both contain similar active ingredients and can lead to an overdose.

Can I take phentermine and Evran together?

Yes, it is safe to take phentermine and Evran together.

Can I take smellaid and Evran together?

Yes, it is safe to take smellaid and Evran together.

Can I take Zofran and Evran together?

Yes, it is safe to take Zofran and Evran together.

Can I take Allegra and Evran together?

Yes, it is safe to take Allegra and Evran together.

Can I take a multivitamin and Evran together?

Yes, it is safe to take a multivitamin and Evran together.

Can I take Tagamet and Evran together?

No, it is not recommended to take Tagamet and Evran together as they both contain similar active ingredients and can lead to an overdose.

Can Evran cause stomach pain?

Yes, Evran can cause stomach pain in some people. If you experience stomach pain while taking Evran, it is important to contact your doctor.

Can I take ibuprofen and Evran at the same time?

Yes, it is safe to take ibuprofen and Evran at the same time.

Can I take aspirin and Evran at the same time?

Yes, it is safe to take aspirin and Evran at the same time.

Can Evran cause headaches?

Yes, Evran can cause headaches in some people. If you experience headaches while taking Evran, it is important to contact your doctor.

Can I take Benadryl and Evran together?

Yes, it is safe to take Benadryl and Evran together.

Can I take Tylenol and Evran together?

Yes, it is safe to take Tylenol and Evran together.

Can I take Prevacid and Evran together?

No, it is not recommended to take Prevacid and Evran together as they both contain similar active ingredients and can lead to an overdose.

Can I take Evran and Pepcid AC together?

No, it is not recommended to take Evran and Pepcid AC together as they both contain similar active ingredients and can lead to an overdose.

Can Evran cause dizziness?

Yes, Evran can cause dizziness in some people. If you experience dizziness while taking Evran, it is important to contact your doctor.