Epidual
Epidual Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Epidual is a brand name. Its generic name is Adapalene + Benzoyl peroxide.
Adapalene + Benzoyl Peroxide Introduction
Adapalene + Benzoyl Peroxide is a combination of two medications that are used to treat acne. Adapalene is a topical retinoid used for the treatment of acne, and Benzoyl Peroxide is an antimicrobial agent that works by killing the bacteria that are associated with acne.
Uses for Adapalene + Benzoyl Peroxide
Adapalene + Benzoyl Peroxide is used to treat severe acne, which can include blackheads, whiteheads, and other pimples on the face, chest, and back. It is most commonly used in combination with other topical medications for the treatment of severe acne.
Mechanism of Action
Adapalene works by affecting the growth of skin cells and reducing inflammation. It is an anti-inflammatory and anti-oxidant agent that helps to reduce the severity of acne. Benzoyl Peroxide works by killing the bacteria associated with acne, and also helps to reduce skin irritation and inflammation.
How Long Does It Take to Work?
It may take several weeks of using Adapalene + Benzoyl Peroxide before you begin to see improvements in your acne. The exact amount of time depends on your skin type and the severity of your acne.
Absorption
Adapalene has been shown to be absorbed through the skin, and then metabolized by the liver. Benzoyl Peroxide also can be absorbed through the skin, and has been shown to have low systemic absorption.
Route of Elimination
Adapalene is eliminated by metabolism and excretion in the bile. Benzoyl Peroxide is removed from the body by gastrointestinal metabolism and excretion in feces and urine.
Dosage
The usual starting dose of Adapalene + Benzoyl Peroxide is one application of the product twice per day to affected areas. If you experience side effects, your doctor may adjust your dose up or down. It is important to follow your doctor's instructions when using this product.
Administration
Adapalene + Benzoyl Peroxide should be applied to the affected area of skin once or twice per day, as directed by your doctor. The product should be applied to the entire affected area, avoiding contact with the eyes, mouth, or any area of broken or irritated skin.
Side Effects
Common side effects with Adapalene + Benzoyl Peroxide include skin irritation, dryness, redness, burning, stinging, and/or peeling. If you experience any of these side effects, you should contact your doctor right away. More serious side effects, such as swelling, itching, hives, or difficulty breathing should be reported to your doctor immediately.
Toxicity
Adapalene and Benzoyl Peroxide are both considered to be safe and effective medications when used as directed. Overdose of Adapalene + Benzoyl Peroxide is unlikely, but if an overdose is suspected, seek emergency medical attention.
Precautions
It is important to use Adapalene + Benzoyl Peroxide as directed by your doctor to help reduce the risk of side effects. Avoid contact with the eyes and mouth, and avoid applying the product to any area of broken or irritated skin. Do not use any other topical acne medications when using Adapalene + Benzoyl Peroxide.
Interactions
There are no known drug interactions associated with Adapalene + Benzoyl Peroxide, but it is important to mention any allergies or medications that you are taking to your doctor before beginning treatment.
Disease Interactions
Adapalene + Benzoyl Peroxide may not be recommended for use if you have a history of eczema or any skin sensitivity. Your doctor may need to adjust your dose if you have any existing medical conditions or other medications that you are taking.
Drug Interactions
It is important to tell your doctor about any medications that you are taking before using Adapalene + Benzoyl Peroxide. This medication may interact with certain other drugs, including oral retinoids, antibiotics, benzoyl peroxide, and sulfur-containing drugs.
Food Interactions
Adapalene + Benzoyl Peroxide is not known to interact with any foods or beverages.
Pregnancy Use
Adapalene + Benzoyl Peroxide should not be used during pregnancy without first consulting a doctor. It is not known if this medication can cause harm to an unborn baby, and there are limited data about the use of this medication during pregnancy.
Lactation Use
It is not known if Adapalene + Benzoyl Peroxide passes into breast milk, and it is recommended that mothers should not use this medication while breastfeeding.
Acute Overdose
An overdose of Adapalene + Benzoyl Peroxide is unlikely to occur, but if it does, seek emergency medical attention. Symptoms of an overdose may include nausea, vomiting, and/or difficulty breathing.
Contraindication
Adapalene + Benzoyl Peroxide should not be used by patients who are allergic to any of the ingredients.
Use Direction
Adapalene + Benzoyl Peroxide should be used as directed by your doctor. Apply the product to the affected area of skin, usually once or twice per day, as directed. Avoid contact with the eyes, mouth, or any area of broken or irritated skin.
Storage Conditions
Store Adapalene + Benzoyl Peroxide at room temperature, away from direct sunlight and heat. Keep the product out of reach of children and pets.
Volume of Distribution
Adapalene has a volume of distribution of 15-50L/kg, and Benzoyl Peroxide has a volume of distribution of 0.5-1.5L/kg.
Half Life
Adapalene has a terminal half-life of 15 hours, and Benzoyl Peroxide has a terminal half-life of 11 hours.
Clearance
Adapalene is eliminated by metabolism and excretion in the bile, and Benzoyl Peroxide is eliminated by gastrointestinal metabolism and excretion in feces and urine.
Here you find in details version of Epidual
Some Frequently Asked Questions About Epidual
What is Epidual?
Adapalene + Benzoyl Peroxide is a topical medication containing two active ingredients that is used to treat mild to moderate acne. The combination of adapalene and benzoyl peroxide helps to reduce acne lesions, unclog pores, and reduce inflammation associated with acne.
What are the side effects of Epidual?
The most common side effects of Adapalene + Benzoyl Peroxide include skin irritation, redness, burning, dryness, itching, stinging, and peeling. Other rare but serious side effects such as rash, hives, and swelling can also occur.
Is Epidual safe?
Adapalene + Benzoyl Peroxide is generally considered safe when used as directed. It is important to follow the instructions on the package insert of the medication and ask your healthcare provider any questions you may have about your treatment.
Who should not use Epidual?
Adapalene + Benzoyl Peroxide should not be used by children under the age of 12, by women who are pregnant or breastfeeding, and by people with very sensitive skin or a history of severe allergies.
Is there a generic form of Epidual?
Yes, a generic form of Adapalene + Benzoyl Peroxide is available. There are a few brands of generic Adapalene + Benzoyl Peroxide, including Differin XP.
How often should Epidual be applied?
Adapalene + Benzoyl Peroxide should be applied once daily or according to the package instructions. Do not exceed the recommended amount.
What should I do if I forget to apply Epidual?
If you forget to apply Adapalene + Benzoyl Peroxide, you should apply it as soon as you remember. Do not double up on doses of the medication.
Can I use makeup while using Epidual?
Yes, you can use makeup while using Adapalene + Benzoyl Peroxide. It is recommended to use water-based or oil-free makeup and non-comedogenic moisturizers.
How long does it take for Epidual to work?
It may take several weeks for Adapalene + Benzoyl Peroxide to start working. Your skin will need some time to adjust to the medication, and you may experience some skin irritation or dryness during this period. However, you should start seeing improvements in your skin over time.
Is Epidual expensive?
Adapalene + Benzoyl Peroxide may be expensive depending on your insurance coverage. If it is not covered by your insurance, you may be able to find generic versions of the medication that are more affordable.
What should I do if I experience increased redness, burning, itching, or peeling?
If you experience increased redness, burning, itching, or peeling while using Adapalene + Benzoyl Peroxide, you should contact your healthcare provider. They may recommend adjusting your dosage or discontinuing use of the medication if necessary.
Can I use Epidual with other acne medications?
It is generally not recommended to use Adapalene + Benzoyl Peroxide with other acne medications. Talk to your healthcare provider about the best way to manage your acne.
Should I use Epidual all over my face or just on problem areas?
Adapalene + Benzoyl Peroxide should be applied all over the face, not just on problem areas. Even if you only have a few blemishes, it is important to apply the medication all over your face to get the best results.
Is Epidual good for preventing acne?
Yes, Adapalene + Benzoyl Peroxide is effective for preventing acne. It helps to reduce oil production, unclog pores, reduce inflammation, and prevent new blemishes from forming.
Can I use Adapalene + Benzoyl Peroxide on other parts of the body?
No, Adapalene + Benzoyl Peroxide should only be used on the face. If you experience acne on other areas of body, you should talk to your healthcare provider about the best treatment.
Is Adapalene + Benzoyl Peroxide suitable for sensitive skin?
No, Adapalene + Benzoyl Peroxide is not suitable for people with sensitive skin or a history of severe allergies. Talk to your healthcare provider if you have any concerns about using this medication.
Does Adapalene + Benzoyl Peroxide make my skin more sun sensitive?
Yes, Adapalene + Benzoyl Peroxide makes the skin more sun sensitive, so it is important to wear sunscreen and protective clothing when spending time outdoors to protect your skin from UV rays.
Can I use Adapalene + Benzoyl Peroxide with other skincare products?
Yes, you can use other skincare products with Adapalene + Benzoyl Peroxide, but you should avoid products that contain alcohol, fragrances, and harsh ingredients, as these may cause skin irritation. It is also important to avoid using other acne medications at the same time.
Should I avoid waxing or hair removal while using Adapalene + Benzoyl Peroxide?
Yes, Adapalene + Benzoyl Peroxide may make the skin more sensitive to waxing and other types of hair removal. You should refrain from these activities while using the medication.
Should I use Adapalene + Benzoyl Peroxide at night or in the morning?
Adapalene + Benzoyl Peroxide should be applied at night, after thoroughly cleansing and drying the skin. Do not apply to wet or damp skin.
Can Adapalene + Benzoyl Peroxide treat cystic acne?
Adapalene + Benzoyl Peroxide may help to reduce the appearance of cystic acne, but it may not completely clear up cystic acne. It is important to talk to your healthcare provider about the best way to manage cystic acne.
How long can I safely use Adapalene + Benzoyl Peroxide?
Adapalene + Benzoyl Peroxide is generally considered safe for long-term use, but it may cause skin irritation over time. If you experience increased skin irritation, you should talk to your healthcare provider.
Can I use Adapalene + Benzoyl Peroxide on broken skin?
No, Adapalene + Benzoyl Peroxide should not be used on broken skin. If you have any open sores on your skin, you should wait until they have healed before using the medication.
Should I avoid certain foods while using Adapalene + Benzoyl Peroxide?
No, there are no foods you should specifically avoid while using Adapalene + Benzoyl Peroxide. However, it is important to maintain a balanced diet with plenty of fruits and vegetables and a healthy amount of water.
Can Adapalene + Benzoyl Peroxide be used on the chest or back?
No, Adapalene + Benzoyl Peroxide should only be used on the face. If you experience acne on the chest or back, talk to your healthcare provider about the best treatment for these areas.
Should I avoid exercise while using Adapalene + Benzoyl Peroxide?
No, you should not avoid exercise while using Adapalene + Benzoyl Peroxide. However, it is important to wash off sweat and makeup after exercising to prevent acne.
What is the difference between Adapalene and Benzoyl Peroxide?
Adapalene is a retinoid used to reduce acne and inflammation, while Benzoyl Peroxide is an antibacterial agent used to kill bacteria and reduce oil production. Both ingredients are effective for treating acne, but they work in different ways.
Can I use Adapalene + Benzoyl Peroxide with birth control pills?
Yes, Adapalene + Benzoyl Peroxide can be used with birth control pills. However, you should talk to your healthcare provider about any potential interactions between the medications.
What happens if I get Adapalene + Benzoyl Peroxide in my eyes?
If you get Adapalene + Benzoyl Peroxide in your eyes, rinse them out with water immediately. If you experience any pain, redness, swelling, or discomfort, seek medical attention.
Is Adapalene + Benzoyl Peroxide safe to use during pregnancy?
No, Adapalene + Benzoyl Peroxide is not safe to use during pregnancy. Talk to your healthcare provider about safe and effective alternative treatments.
What is the best way to store Adapalene + Benzoyl Peroxide?
Adapalene + Benzoyl Peroxide should be stored away from light and heat in a cool, dry place. It should also be kept out of reach of children and pets.
How should Adapalene + Benzoyl Peroxide be applied?
Adapalene + Benzoyl Peroxide should be applied to a clean, dry face once daily or according to the package instructions. Always followed the directions on the package insert when applying the medication.
Can I get Adapalene + Benzoyl Peroxide over the counter?
Yes, Adapalene + Benzoyl Peroxide is available over the counter. However, it is important to talk to a healthcare professional to make sure it is right for you before using it.
Should I use a moisturizer with Adapalene + Benzoyl Peroxide?
Yes, it is important to use a non-comedogenic moisturizer with Adapalene + Benzoyl Peroxide to help reduce skin irritation and dryness. Your healthcare provider can recommend a suitable moisturizer.
Can I use a toner while using Adapalene + Benzoyl Peroxide?
Yes, you can use a toner while using Adapalene + Benzoyl Peroxide. However, it is important to choose an alcohol-free, non-comedogenic toner and use it sparingly to prevent skin irritation.
Can I use Adapalene + Benzoyl Peroxide while taking antibiotics?
Yes, Adapalene + Benzoyl Peroxide can be used with antibiotics. However, it is important to talk to your healthcare provider about potential interactions between the medications.
Should I avoid going in the sun while using Adapalene + Benzoyl Peroxide?
Yes, you should avoid excessive sun exposure while using Adapalene + Benzoyl Peroxide as it can make the skin more sensitive to UV rays. Wear sunscreen and protective clothing when spending time outdoors.
Does Adapalene + Benzoyl Peroxide have any other uses?
Adapalene + Benzoyl Peroxide is generally used to treat mild to moderate acne. It is not recommended for any other uses.
Can Adapalene + Benzoyl Peroxide cause discoloration of the skin?
Adapalene + Benzoyl Peroxide may cause discoloration of the skin in some people. If you experience discoloration, you should talk to your healthcare provider. Discoloration may go away over time when use of the medication is discontinued.