Emer
Emer Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Emer is a brand name. Its generic name is Phenobarbital.
Emer Introduction
Emer is a barbiturate with sedative-hypnotic, anticonvulsant, and antiarrhythmic properties; it is also used as an adjunct in the management of pain. Emer is used in the short-term treatment of severe insomnia. It is also used in seizure disorders, particularly when other medications do not control the seizures.
Uses for Emer
Emer is primarily used in the treatment of seizure disorders, including partial seizures, tonic-clonic (generalized) seizures, and mixed seizure patterns. It is also used as a sedative-hypnotic and an adjunctive therapy for the treatment of pain.
Mechanism of Action
Emer has an encephalodepressant action, possibly via binding to GABAA receptors. This action produces an anxiolytic effect, as well as decreased seizure activity. It also has a tranquilizing effect.
How Long Does It Take to Work?
The onset of action of phenobarbital is rapid, usually within minutes, and the duration of action is typically 12-24 hours.
Absorption
Emer is rapidly and almost completely absorbed after oral administration, reaching peak serum concentrations within 1-2 hours.
Route of Elimination
Emer is metabolized in the liver and excreted via the kidneys. Approximately 70-90% of a dose is eliminated in the urine as glucuronide conjugates within 24 hours.
Dosage
The usual dose for adults is 1.5-3 mg/kg a day in two or three divided doses. The usual dose for children is 2-5 mg/kg a day in two or three divided doses. If the dose is taken twice daily, the dose should be taken at bedtime and at noon for best effects.
Administration
Emer should be taken orally with a glass of water. It should be taken with food or milk if GI irritation occurs. The tablets should not be crushed, chewed, or dissolved in liquid.
Side Effects
Common side effects of phenobarbital include confusion, drowsiness, dizziness, impaired coordination, headache, nausea, vomiting, blurred vision, and rash. Rarely, phenobarbital can cause an allergic reaction, which may include difficulty breathing, hives, swelling of the face, lips, tongue, or throat.
Toxicity
Overdose of phenobarbital can lead to central nervous system depression, coma, respiratory depression, and death. The symptoms of overdose include confusion, disorientation, slurred speech, tachycardia, and impaired motor coordination.
Precautions
Emer should be used with caution in patients with liver disease, as the drug is metabolized in the liver. It should also be used with caution in elderly patients, as they may be more sensitive to the drug's effects. It should be used with caution in patients with a history of alcoholism or drug addiction.
Interaction
Emer may interact with other drugs, including other anticonvulsants, alcohol, antidepressants, and narcotic pain relievers. It may also interact with other substances, such as alcohol, caffeine, and tobacco. These interactions may increase or decrease the effectiveness of the medication.
Disease Interaction
Emer may interact with certain diseases, including liver and kidney disease, depression, and mental illness. Patients with any of these conditions should consult their healthcare provider before taking this medication.
Drug Interactions
Emer may interact with other medications, including anticonvulsants, antidepressants, anticholinergics, antiarrhythmics, sedatives/hypnotics, warfarin, and other CNS depressants. Patients should inform their healthcare provider about any medications they are taking before taking phenobarbital.
Food Interactions
Emer may interact with certain foods, such as alcohol, caffeine, and tobacco. Patients should inform their healthcare provider about any foods they are consuming before taking this medication.
Pregnancy Use
Emer should not be used during pregnancy unless the benefits outweigh the risks. Patients should inform their healthcare provider if they are pregnant or planning to become pregnant before taking this medication.
Lactation Use
Emer is excreted in breast milk and may cause undesirable effects in a nursing infant. Patients should inform their healthcare provider if they are breastfeeding before taking this medication.
Acute Overdose
An overdose of phenobarbital can be dangerous and may require immediate medical attention. Symptoms of an overdose include confusion, disorientation, slurred speech, tachycardia, impaired motor coordination, and coma. Patients should seek medical attention immediately if they suspect they have overdosed.
Contraindication
Emer is contraindicated in patients with allergies to the drug, in patients with severe liver or kidney disease, in those with a history of porphyria, and in those with a history of drug abuse or addiction. Patients should inform their healthcare provider if they have any of these conditions before taking this medication.
Use Direction
Emer should be taken orally with a glass of water. The tablets should not be crushed, chewed, or dissolved in liquid. The usual dose for adults is 1.5-3 mg/kg a day in two or three divided doses. The usual dose for children is 2-5 mg/kg a day in two or three divided doses. If the dose is taken twice daily, the dose should be taken at bedtime and at noon for best effects.
Storage Conditions
Emer should be stored at room temperature away from light, heat, and moisture. It should be kept out of the reach of children and pets.
Volume of Distribution
Emer has a volume of distribution of 1 to 5 L/kg.
Half-Life
The half-life of phenobarbital is 3-6 hours.
Clearance
Emer has a clearance of 0.2-0.9 mL/min/kg.
Here you find in details version of Emer
Some Frequently Asked Questions About Emer
30What is Emer?
Emer is a long-acting barbiturate drug that is used mainly as an anticonvulsant and sedative. It is also used to treat seizures, insomnia, and other sleep disorders.
How does Emer work?
Emer works by increasing the action of gamma-Aminobutyric acid (GABA) in the brain, a neurotransmitter that helps regulate neural activity. By increasing the action of GABA, phenobarbital reduces the activity of nerve cells in the brain, which has a calming and sedative effect.
What are the common side effects of Emer?
The most common side effects of Emer are drowsiness, fatigue, confusion, dizziness, nausea, blurred vision, and difficulty concentrating. More serious side effects include depression, headaches, and rashes.
Who should not take Emer?
Emer should not be taken by those who have a history of drug or alcohol abuse, are pregnant or breastfeeding, are allergic to barbiturates, have a history of mental illness, have liver or kidney disease, or have low blood pressure.
Is Emer addictive?
Yes, Emer has a potential for addiction and dependence, especially when taken in large doses or for long periods of time. Those who have a history of drug or alcohol abuse should be monitored closely if taking Emer.
How should I take Emer?
Emer should be taken as prescribed by your doctor. It is usually taken 1-4 times per day, with or without food. Do not take more than the prescribed dose, and do not stop taking the medication without first consulting your doctor.
What are the withdrawal symptoms of Emer?
Common withdrawal symptoms of Emer include insomnia, anxiety, irritability, tremors, sweating, confusion, and nausea. More severe symptoms may include seizures, hallucinations, and delirium. If you experience any of these symptoms after stopping the medication, contact your doctor immediately.
What should I do if I miss a dose of Emer?
If you miss a dose of Emer, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. Do not take double doses to make up for a missed one.
How long does it take for Emer to start working?
It usually takes 1-4 hours for Emer to start working, although it can take longer in some individuals. The effects of the drug can last up to 8 hours.
Does Emer interact with other drugs?
Yes, Emer can interact with certain drugs and supplements. Before taking Emer, tell your doctor about all of the medications, vitamins, and herbal supplements that you are currently taking. Your doctor may change the dose or frequency of your other medications.
Can I drink alcohol while taking Emer?
No, you should not drink alcohol while taking Emer or any other barbiturates, as drinking alcohol can increase the effects of the drug. Drinking alcohol with Emer can cause drowsiness, confusion, and difficulty breathing.
What are the symptoms of an overdose of Emer?
Symptoms of an overdose of Emer include slow and shallow breathing, confusion, loss of consciousness, and seizures. If you think that you or someone else has taken too much of this drug, seek medical attention immediately.
Do I need to take special precautions while taking Emer?
Yes, you should take special precautions while taking Emer. Do not drive or operate heavy machinery while taking this medication. Also, avoid drinking alcohol and using other medications that may cause drowsiness or dizziness.
Can I take Emer while pregnant or breastfeeding?
No, Emer is not recommended for pregnant or nursing women. The drug can pass into breast milk and can harm the developing fetus.
Is Emer available over the counter?
No, Emer is a prescription medication and is not available over the counter.
Can I take Emer with other drugs?
Yes, Emer can be taken with other drugs such as pain relievers and anti-anxiety medications. Talk to your doctor before taking any medications together.
Does Emer affect blood pressure?
Yes, Emer can affect blood pressure. If you have a history of low blood pressure, your doctor may monitor your levels closely.
Is Emer habit-forming?
Yes, Emer is habit-forming, especially when taken in large doses or for long periods of time. It is important to follow the instructions of your doctor when taking this medication.
What are the long-term effects of Emer?
Long-term use of Emer can lead to dependency, impaired cognitive functioning, and depression. It is important to talk to your doctor before starting or stopping this medication.
Does Emer reduce seizure threshold?
Yes, Emer can reduce the seizure threshold in some people, especially those who have a history of seizures. If you have a history of seizures, talk to your doctor before taking this medication.
Can I take other medications while taking Emer?
Yes, you can take other medications while taking Emer. However, it is important to tell your doctor about all of the other medications and supplements that you are taking, as there is the potential for interactions between drugs.
Should I take Emer in the morning or at night?
Emer can be taken either in the morning or at night, depending on the dose. Your doctor will recommend the best time to take the medication.
Can Emer be used to treat anxiety?
Yes, Emer can be used to treat anxiety. However, it is important to talk to your doctor before taking this medication, as it is not intended for long-term use.
Is Emer safe for children?
Yes, Emer is approved for use in children over the age of 6 months. However, it is important to talk to your doctor before starting any medication for a child.
Is Emer used to treat epilepsy?
Yes, Emer is sometimes used to treat epilepsy. It is important to talk to your doctor before starting or stopping any medication for epilepsy.
How long can I take Emer?
You should take Emer for as long as your doctor advises, in order to get the most benefit from it. Do not stop taking the medication without discussing it with your doctor.
Can Emer cause weight gain?
Yes, Emer can cause weight gain in some people. If you experience weight gain while taking the medication, talk to your doctor.
Can Emer cause hair loss?
Yes, Emer can cause hair loss in some individuals. If you experience hair loss while taking the medication, talk to your doctor.
Does Emer cause liver damage?
Yes, long-term use of Emer can cause liver damage. If you have a history of liver disease, talk to your doctor before taking this medication.
Does Emer interact with birth control?
Yes, Emer can interact with some forms of birth control. If you are taking birth control, it is important to talk to your doctor before taking Emer.
Can Emer be used to treat depression?
No, Emer is not recommended for the treatment of depression. It should only be used to treat seizures or other sleep disorders. Talk to your doctor about other medications that may be used to treat depression.
Does Emer cause constipation?
Yes, Emer can cause constipation. If you experience constipation while taking the medication, talk to your doctor.
Can Emer be used to treat insomnia?
Yes, Emer can be used to treat insomnia in some cases. However, it is important to talk to your doctor before taking Emer for insomnia, as it may not be the best option for everyone.
Does Emer interact with other medications?
Yes, Emer can interact with other medications. Before taking Emer, tell your doctor about all of the medications, vitamins, and herbal supplements that you are currently taking.
What happens if I take too much Emer?
Taking too much Emer can cause serious side effects such as slow and shallow breathing, confusion, and loss of consciousness. If you think that you or someone else has taken too much of this medication, seek medical attention immediately.
Does Emer cause dizziness?
Yes, Emer can cause dizziness in some people. If you experience dizziness while taking the medication, talk to your doctor.