Elidel
Elidel Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Elidel is a brand name. Its generic name is Pimecrolimus.
Introduction
Elidel is an immune-modulating topical cream or ointment approved for use in adults and children, ages 2 and up to treat mild to moderate atopic dermatitis (eczema) and to reduce the need for topical steroid therapy. It is also approved for the short-term management of facial and intertriginous dermatitis.Uses For
Elidel is used to treat mild to moderate forms of atopic dermatitis, including facial and intertriginous dermatitis. It is approved for use in adults and children, ages 2 and up, and in persons with sensitive skin, like those with atopic dermatitis.Mechanism of action
Elidel works by inhibiting the production of certain inflammatory cytokines involved in the skin's inflammatory response. It is believed to work by blocking the action of the inflammatory molecule T-cell expression of interleukin-2 (IL-2), which is a major mediator responsible for increased inflammation in atopic dermatitis.How Long Does it Take to Work?
The effects of pimecrolimus can be seen very quickly with visible improvement typically being noticed within 2-3 days of starting therapy. However, full therapeutic effects may take several weeks to become noticeable.Absorption
Elidel is absorbed through the skin. The degree of absorption depends on the individual, area of application and overall skin condition. absorption of the drug is higher in damaged skin areas as compared to normal skin.Route of Elimination
Elidel is mostly excreted through urine and feces. Very little of the drug is known to be metabolized.Dosage
The dose of Elidel used depends on the age of the patient, the severity of the condition being treated, and the overall health of the patient. Dosage for adults and children, ages 2 and over: apply Elidel cream/ointment to affected areas of the skin two times per day or as directed by a doctor. The maximum total daily dose should not exceed 50 g.Administration
Elidel should be applied to the affected areas of the skin twice daily or as directed by a doctor. After applying the cream/ointment, the area should be left uncovered and not bandaged or covered. It should not be applied to large areas of the skin, open wounds, or infection.Side Effects
Elidel is generally well tolerated but may cause side effects including burning, stinging, irritation, itching, rash, and redness at the site of application. If these side effects are severe or persistent, contact your doctor.Toxicity
The use of topical pimecrolimus is generally considered safe. If taken orally, pimecrolimus can cause side effects including nausea, vomiting, abdominal pain, fatigue, dizziness, headaches, and an increased risk of infection.Precautions
It is important to use pimecrolimus exactly as prescribed by your doctor. Do not use more or less of it than prescribed. It should not be applied to large areas of the skin, open wounds, broken skin, or an infection.Interactions
Elidel may interact with other medications, including topical and oral corticosteroids, antibiotics, antifungals, and antivirals. before using any medication, including pimecrolimus, you should always talk to your doctor.Disease Interactions
Elidel may interfere with certain medical conditions or increase the risk of certain diseases. You should always inform your doctor if you have any other medical conditions, especially if you have had skin cancer.Drug Interactions
Elidel may interact with certain drugs, including topical corticosteroids, antibiotics, antifungals, and antivirals. Before taking any medications, including pimecrolimus, you should always talk to your doctor.Food Interactions
There are no known food interactions with pimecrolimus.Pregnancy Use
Elidel cream/ointment is not recommended for use in pregnant women. If you are pregnant or planning to become pregnant, talk to your doctor about the risks and benefits of using this medication.LactationUse
Elidel ointment should not be used while you are breastfeeding as it is not known if it passes into breast milk. Talk to your doctor before taking any medications, including pimecrolimus, while you are breastfeeding.Acute Overdose
Do not use more medication than prescribed. If you accidentally take too much, seek immediate medical attention or contact your doctor. Symptoms of an overdose may include nausea, vomiting, abdominal pain, dizziness, and headache.Contraindication
Elidel cream/ointment is contraindicated in patients with known or suspected hypersensitivity to any component of this product.Use Direction
Elidel should be applied directly to the affected area of skin twice daily or as directed by a doctor. Do not apply to large areas of the skin, open wounds, or infected skin. Always wash your hands before and after applying the medication.Storage Condition
Elidel cream/ointment should be stored at room temperature in a cool and dry place, out of direct sunlight and away from heat and moisture. Do not freeze or expose to temperatures above 77°F (25°C).Volume of Distribution
Elidel has a volume of distribution of 8.2 L/kg in humans.Half Life
Elidel has a half life of 4-5 hrs in humans.Clearance
Elidel has a clearance rate of 0.3-0.4 L/kg/hr in humans.Here you find in details version of Elidel
Some Frequently Asked Questions About Elidel
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