DuoCain

DuoCain Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? DuoCain is a brand name. Its generic name is Lidocaine + Prilocaine.

Introduction of Lidocaine and Prilocaine

Lidocaine and Prilocaine are local anesthetics that are combined to form a eutectic mixture of local anesthetics (EMLA). They are both amide-type anesthetics.

Uses for Lidocaine and Prilocaine

EMLA is used on normal intact skin as a topical anaesthetic to relieve pain before minor procedures such as venipuncture and laser treatment. It can be used to reduce discomfort during laser tattoo removal and can also be used to anaesthetize the perianal area during a rectal exam.

Mechanism of Action

Lidocaine works by temporarily disabling the nerves that carry pain signals from the skin to the brain while Prilocaine reduces the amount of neurotransmitters that are released when a nerve is stimulated. Together, they provide a stronger and longer lasting anaesthesia than either anesthetic alone.

How Long Does It Take to Work?

The effects of EMLA usually begin within 5 minutes of application and last up to four hours.

Absorption

EMLA is quickly and almost completely absorbed through the stratum corneum (outer layer of skin). It is then metabolized in the dermis (middle layer) before entering the bloodstream.

Route of Elimination

Lidocaine and Prilocaine are both metabolized in the liver and eliminated through the kidneys.

Dosage and Administration

EMLA is available as a cream that should be applied to affected area, as instructed by your doctor. Depending on the area being treated, your doctor may tell you to apply the cream 30 minutes to a few hours before your procedure.

Side Effects of Lidocaine and Prilocaine

The most common side effects of EMLA are reversible local skin reactions such as:

• Burning sensation
• Pain
• Itching

Toxicity

Overdose symptoms may include confusion, numbness, slowed breathing, seizures, unconsciousness, coma, and death. If an overdose occurs, get emergency medical help.

Precautions

EMLA should not be used in patients who are sensitive to any of its components, or have open wounds, cuts, scrapes, or sores near the site of application. It should also not be used in areas affected by frostbite and should be avoided in infants and premature babies.

Interaction

EMLA should not be used with other topical preparations or medications that may affect the skin.

Drug Interaction

EMLA should not be used with sedatives or anxiety drugs, such as alprazolam (Xanax) or lorazepam (Ativan). It may interact with other medications that can cause drowsiness, such as opioid pain relievers or antidepressants.

Food Interactions

No food interactions have been reported.

Pregnancy Use

Lidocaine and Prilocaine have not been studied during pregnancy and should be used with caution in pregnant women.

Lactation Use

EMLA has not been evaluated in lactating women and should be used with caution.

Acute Overdose

In cases of overdose, supportive measures, including airway support, should be instituted immediately. Activated charcoal may be administered. Hemodialysis is not likely to be beneficial in removing Lidocaine and Prilocaine as they are highly bound to plasma proteins.

Contraindication

EMLA should not be used in patients who are sensitive to any of its components, or have open wounds, cuts, scrapes, or sores near the site of application. It should also not be used in areas affected by frostbite and should be avoided in infants and premature babies.

Use Direction

EMLA should be applied to the affected area once or twice daily, as directed by your doctor. Cover the area with a bandage or plastic wrap after applying.

Storage Conditions

Store at room temperature between 15-30°C. Do not freeze.

Volume of Distribution

The volume of distribution of Lidocaine and Prilocaine is approximately 2.3L/kg.

Half Life

The half-life of Lidocaine and Prilocaine is approximately 2.2 hours.

Clearance

The clearance of Lidocaine and Prilocaine is approximately 0.55L/kg/h.

Here you find in details version of DuoCain

Some Frequently Asked Questions About DuoCain

What is Lidocaine and Prilocaine?

Lidocaine and Prilocaine are topical anesthetics used to reduce skin sensation to stimulate pain relief before superficial medical treatments.

What is DuoCain?

DuoCain is a combination of the two topical anesthetics Lidocaine and Prilocaine, which work together to provide a more effective solution for pain relief.

How do DuoCain work?

DuoCain work by blocking pain signals from reaching the brain, thus allowing for increased numbing of the area. The combination provides additional pain relief compared to a single anesthetic.

What is DuoCain used for?

DuoCain is most commonly used to provide topical anesthesia prior to minor medical procedures such as laser hair removal, dermabrasion, and surface wound repairs.

Is DuoCain safe to use?

DuoCain is generally safe to use, though some people may experience minor side effects depending on their individual sensitivity. If any discomfort or adverse reactions occur, stop using the product and contact a medical professional.

What are the side effects of DuoCain?

Side effects of DuoCain may include skin irritation, redness, swelling, burning, itching, or numbness. If any of these side effects occur, stop using the product and contact a medical professional.

Can I use DuoCain while pregnant?

It is not recommended to use DuoCain while pregnant. Consult with your physician before using any topical anesthetics during pregnancy.

Where can I purchase DuoCain?

You can purchase DuoCain from most major retailers as well as online. Make sure to consult your doctor before using any topical anesthetics.

How should DuoCain be applied?

DuoCain should be applied as directed by the manufacturer or as directed by your doctor. Make sure to carefully follow instructions to ensure safe and effective use.

How long does DuoCain last?

The effects of DuoCain typically last anywhere from 1 to 2 hours, but the exact duration of action will depend on the individual and the type of procedure being performed.

How long does it take for DuoCain to take effect?

The effects of DuoCain usually begin to take effect within 10-15 minutes after being applied.

Do I need a prescription for DuoCain?

No, a prescription is not necessary in order to purchase DuoCain.

What should I do if I accidentally get DuoCain in my eyes?

If DuoCain is accidentally applied in the eye, rinse out the eye with cool water and contact a doctor immediately.

What should I do if I have an allergic reaction to DuoCain?

If you are experiencing an allergic reaction to DuoCain, immediately discontinue use and seek medical attention.

Can I use DuoCain on open wounds?

No, it is not recommended to use DuoCain on open wounds. Consult your doctor to find a suitable anesthetic for open-wound procedures.

Can I use DuoCain on children?

It is not recommended to use DuoCain on children. If a topical anesthetic is necessary for medical procedures, consult your doctor for an appropriate alternative for children.

Does DuoCain cause scarring?

No, DuoCain is not known to cause scarring. However, some medical procedures may cause scarring regardless of anesthetic used.

Can I use DuoCain on my pets?

No, DuoCain is intended for use in humans only and should not be used on pets.

Does DuoCain enter the bloodstream?

Yes, DuoCain can enter the bloodstream, though this is typically only possible with prolonged use or overapplication of the product.

Is it safe to use DuoCain on broken skin?

No, it is not recommended to use DuoCain on broken or damaged skin.

Does DuoCain work on tattoos?

No, DuoCain is not intended for use on tattoos or permanent makeup.

Should I avoid certain activities after using DuoCain?

Yes, it is important to avoid activities that require alertness as DuoCain can cause some dizziness and drowsiness.

Can I use DuoCain long term?

No, it is not recommended to use DuoCain long term or on a frequent basis.

Should I wash off DuoCain after the procedure?

Yes, it is recommended to wash off any remaining DuoCain after the procedure is completed.

Is DuoCain type of numbing cream?

Yes, DuoCain is a type of topical anesthetic, which causes numbness and helps to reduce pain prior to superficial medical treatments.

What is the difference between Lidocaine and DuoCain?

The difference between Lidocaine and DuoCain is that DuoCain uses a combination of two topical anesthetics, which work together to provide a more effective solution for pain relief.

Can DuoCain make the skin numb?

Yes, DuoCain can make the skin numb, as it is a topical anesthetic.

Can I use DuoCain to treat a sunburn?

No, it is not recommended to use DuoCain to treat a sunburn as it is intended for use prior to superficial medical treatments.

Can I use DuoCain on cuts and scrapes?

No, it is not recommended to use DuoCain on cuts and scrapes as it is intended for use prior to superficial medical treatments. Consult your doctor for an appropriate alternative.

What is the recommended dosage of DuoCain?

The recommended dosage of DuoCain will depend on individual and the type of procedure being performed. Consult with your doctor for the most appropriate dosage.

Can I use DuoCain on my face?

Yes, DuoCain can be used on the face, though it should be used as directed by the manufacturer or as directed by your doctor.

Can I use DuoCain while breastfeeding?

It is not recommended to use DuoCain while breastfeeding. Consult with your physician before using any topical anesthetics while breastfeeding.

Can I use DuoCain before getting a tattoo?

No, it is not recommended to use DuoCain before getting a tattoo, as it is intended for use prior to superficial medical treatments. Consult your doctor for an appropriate alternative.

Can I use DuoCain for other medical procedures?

Yes, DuoCain can be used for other medical procedures, though it is important to consult your doctor before using a topical anesthetic for any medical procedure.

When should I stop using DuoCain?

It is recommended to stop using DuoCain when the procedure is finished and any necessary numbing has occurred. Make sure to follow manufacturer instructions when using the product.

Can I use DuoCain after a laser hair removal treatment?

Yes, DuoCain is commonly used prior to laser hair removal treatments. Make sure to follow manufacturer instructions when using the product.

Can I use DuoCain for oral procedures?

No, it is not recommended to use DuoCain for oral procedures. Consult your doctor for an appropriate alternative.

Can I use DuoCain on body piercings?

No, it is not recommended to use DuoCain on body piercings. Consult your doctor for an appropriate alternative.

Does DuoCain interfere with other medications?

Yes, DuoCain may interact with certain medications. Before using the product, consult with your doctor about possible interactions with other medications.

Does DuoCain have any long term effects?

No, DuoCain is not known to have any long term effects. However, using the product on a frequent or long-term basis could lead to sensitization of the skin.

Can I use DuoCain after waxing?

Yes, DuoCain is commonly used prior to waxing treatments. Make sure to follow manufacturer instructions when using the product.