Doxiva

Doxiva Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Doxiva is a brand name. Its generic name is Doxofylline.

Introduction

Doxiva is an oral synthetic xanthine derivative used to treat and prevent wheezing or long-term breathing difficulty in people with asthma or other chronic pulmonary diseases such as COPD or emphysema. It is classified as a bronchodilator.

Uses for

Doxiva’s primary use is to help to open the airways in the lungs as it works as a bronchodilator. It is used in conditions such as asthma, chronic obstructive pulmonary disease (COPD), bronchitis, emphysema, and chronic bronchitis. In addition, Doxiva can also be used to treat nasal congestion, recurrent respiratory infections and difficulty in breathing during exercise.

Mechanism of Action

Doxiva works mainly by opening up the airways in the lungs. It achieves this by inhibiting the chemicals that cause the airways to become constricted or narrow. This relaxes the muscles in the airways allowing them to open wider, which makes it easier for the air to flow in and out of the lungs. This helps to reduce symptoms of asthma and other breathing difficulties as well as reducing the frequency of asthma attacks.

How Long Does it Take to Work?

Doxiva usually takes around 30 minutes to begin to take effect. The maximum effect is usually reached within one to four hours and the effects can last for up to six hours.

Absorption

Doxiva is rapidly and completely absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 1-2 hours of administration.

Route of Elimination

Doxiva is metabolised in the liver and is eliminated mainly by the kidneys. About 10-20% of the administered dose is excreted unchanged in the urine.

Dosage

The dosage of Doxiva will depend on the individual. It is available as 50, 100 and 400 mg tablets and can be taken once or twice a day. It is recommended to take the lowest dose that is effective in controlling the condition. For adults, the usual starting dose is 100 mg twice a day and the maximum dose is 400 mg twice a day.Children aged 6 years and above should take 6-12 mg/kg/day in two to three divided doses.

Administration

Doxiva should be taken exactly as your doctor has prescribed. It should be swallowed as a whole tablet with a glass of water and should not be crushed or chewed. The tablet should be taken before a meal or at bedtime.

Side Effect

The most common side effects of Doxiva are headache, nausea, vomiting, abdominal pain, diarrhoea, and loss of appetite. Other side effects include dizziness, insomnia, dry mouth, and rash.

Toxicity

Doxiva is not usually toxic in therapeutic doses, although an overdose of the drug may lead to serious side effects such as confusion, hallucinations, seizures, tachycardia, and respiratory depression. An overdose can be fatal if not treated immediately.

Precaution

Doxiva should be taken with caution in patients with kidney or liver impairment. It should be used with caution in patients with diabetes, as it may cause a decrease in blood sugar levels. Patients should be advised to monitor blood sugar levels. Patients with a history of seizures should also use caution when taking this drug.

Interaction

Doxiva can interact with certain medications, such as anticoagulants, oral contraceptives, and certain antibiotics. Alcohol can also interact with this drug and should be avoided. Patients should inform their doctor or pharmacist of all medications they are taking.

Disease Interaction

Doxiva should be used with caution in patients with certain diseases as it may worsen symptoms or cause side effects. These include diabetes, kidney or liver impairment, heart failure, an overactive thyroid, and certain eye diseases.

Drug Interactions

Doxiva can interact with certain drugs, including anticoagulants, diuretics, oral contraceptives, certain antibiotics, and other xanthine derivatives. Patients should inform their doctor or pharmacist of all medications they are taking.

Food Interactions

Food should be taken at least 2 hours (1 hour before or 1 hour after) after taking Doxiva to decrease its effects. Patients should avoid caffeine-containing foods and drinks such as coffee, tea, and chocolate during the course of treatment.

Pregnancy Use

Doxiva should be used with caution during pregnancy as it can cross the placenta and potentially cause harm to the fetus. It is not recommended for use during the first trimester of pregnancy.

Lactation Use

It is unknown whether Doxiva is excreted in human breast milk. Therefore, caution should be exercised when administering this drug to nursing mothers.

Acute Overdose

An acute overdose of Doxiva can lead to serious side effects such as confusion, hallucinations, seizures, tachycardia, and respiratory depression. Treatment of an overdose usually includes supportive care and symptomatic treatment.

Contraindication

Doxiva is contraindicated in patients with known hypersensitivity to xanthine derivatives, as well as in patients with severe liver or kidney impairment.

Use Direction

Doxiva should be taken as directed by the doctor or pharmacist. The tablets should be swallowed whole with a glass of water and should not be crushed or chewed. Take the drug at the same time every day and make sure to take the lowest dose that is effective in controlling the condition.

Storage Condition

Doxiva should be stored at a controlled room temperature of 15 to 30°C and must be kept away from light, moisture and heat. The tablets must be stored in a locked container and should be out of reach of children.

Volume of Distribution

The volume of distribution of Doxiva is approximately 0.6 L/kg. It is widely distributed into body tissues.

Half Life

The elimination half life of Doxiva is approximately 3.3 hours although it may vary in different individuals.

Clearance

The total clearance of Doxiva is approximately 17 mL/min/kg. The renal clearance is approximately 15 mL/min/kg.

Here you find in details version of Doxiva

Some Frequently Asked Questions About Doxiva

What is Doxiva?

Doxiva is a medicine used to treat breathing difficulties associated with asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing the air passages and reducing the swelling of the lining of the airways.

Is Doxiva safe to take?

Yes, Doxiva is generally considered safe to take and is used to treat breathing difficulties associated with asthma and COPD. However, it is important to discuss any potential risks or side effects with your doctor before taking this medicine.

How do I take Doxiva?

Your doctor will provide you with instructions on how to take Doxiva correctly. It is important to follow these instructions and take the medicine as directed. In general, Doxiva is usually taken twice daily and should be taken with food.

What are the side effects of Doxiva?

Common side effects of Doxiva can include headache, nausea, stomach pain, and diarrhea. If you experience any severe or persistent side effects or if you have any questions regarding the medicine, contact your doctor as soon as possible.

Can I take Doxiva if I'm pregnant?

It is not recommended to take Doxiva if you are pregnant. If you become pregnant while taking this medicine, you should stop taking it and speak to your doctor right away.

What is the difference between Doxiva and Theophylline?

Both Doxiva and Theophylline are medicines used to treat breathing difficulties associated with asthma and COPD. Theophylline is a shorter-acting medicine than Doxiva and is usually taken four times a day. Doxiva is a longer-acting medicine and is typically taken twice a day.

Can I take other medications while taking Doxiva?

It is important to tell your doctor about all other medications you are taking before starting on Doxiva. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

Can I drink alcohol while taking Doxiva?

It is generally not recommended to drink alcohol while taking Doxiva. Alcohol can increase the risk of side effects and may also decrease the effectiveness of the medicine. If you have any questions or concerns, speak to your doctor.

How long does it take for Doxiva to work?

It usually takes about 48 to 72 hours for Doxiva to reach its full effect. If you have not noticed any improvement in your symptoms after this time, contact your doctor.

Is Doxiva habit-forming?

No, Doxiva is not considered to be habit-forming. However, it is important to take the medicine exactly as prescribed and not to take more than the recommended dosage.

What if I miss a dose of Doxiva?

If you forget to take a dose of Doxiva, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Does Doxiva have any long-term side effects?

The long-term side effects of Doxiva vary depending on the person and the length of time they have been taking it. It is important to speak to your doctor about any potential risks or side effects before taking this medicine.

Can Doxiva cause headaches?

Yes, headaches are a common side effect of taking Doxiva. If you experience any severe or persistent headaches, speak to your doctor.

Can Doxiva make my breathing difficulties worse?

It is important to speak to your doctor if you experience any worsening of your breathing difficulties while taking Doxiva. Your doctor may need to adjust your dosage or recommend another medication.

Do I have to take Doxiva every day?

Yes, you should take Doxiva as directed by your doctor in order to maintain the best possible result. It is important to take this medicine every day as it takes some time for the drug to reach its full effect.

What should I do if I have an allergic reaction to Doxiva?

If you experience any allergic reactions to Doxiva such as difficulty breathing, swelling of the face, lips, or tongue, or hives, stop taking the medicine immediately and seek medical help. Be sure to let your doctor know if you have had any allergic reactions to this medicine in the past.

When can I expect to see results while taking Doxiva?

It typically takes about 48 to 72 hours for Doxiva to reach its full effect. If you have not noticed any improvements in your symptoms after this time, you should discuss this with your doctor.

Can I take Doxiva with other asthma medications?

It is generally safe to take Doxiva with other asthma medications. However, it is important to discuss this with your doctor before taking any other medicines, as they may interact with each other.

Can Doxiva help with difficulty breathing due to COPD?

Yes, Doxiva is used to treat breathing difficulties associated with chronic obstructive pulmonary disease (COPD). It works by relaxing the air passages and reducing the swelling of the lining of the airways.

What should I do if I experience an irregular heartbeat while taking Doxiva?

If you experience an irregular heartbeat or palpitations while taking Doxiva, stop taking the medicine and seek medical help right away. Be sure to let your doctor know if you have had any heart problems in the past.

Does Doxiva cause drowsiness?

Yes, drowsiness is a potential side effect of taking Doxiva. If you experience any drowsiness, you should not operate any heavy machinery or vehicles.

Can I take Doxiva while breastfeeding?

It is generally not recommended to take Doxiva while breastfeeding. If you are breastfeeding and need to take this medicine, you should discuss this with your doctor.

What if I forget to take Doxiva?

If you forget to take a dose of Doxiva, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Can I take Doxiva while pregnant?

It is not recommended to take Doxiva if you are pregnant. If you become pregnant while taking this medicine, you should stop taking it and speak to your doctor right away.

Is it safe to take Doxiva with other medications?

It is important to tell your doctor about all other medications you are taking before starting on Doxiva. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

How much Doxiva should I take?

Your dose of Doxiva will depend on your medical condition and response to treatment. The dose may also be affected by other medications you are taking. You should always follow the instructions of your doctor and take the medicine exactly as directed.

What should I avoid while taking Doxiva?

It is important to avoid alcohol while taking Doxiva, as it may increase the risk of side effects and decrease the effectiveness of the medicine. Additionally, you should not operate any heavy machinery or vehicles, as the medicine may cause drowsiness.

Can I take Doxiva without food?

It is generally recommended to take Doxiva with food. Taking the medicine with food can help to reduce stomach upset and improve absorption of the drug. If you have any questions or concerns, speak to your doctor.

Does Doxiva have any serious side effects?

Yes, there are potential serious side effects associated with the use of Doxiva. These side effects can include shortness of breath, chest pain, irregular heartbeat, seizure, and rash. If you experience any of these symptoms, stop taking the medicine and seek medical help right away.

Can I take other asthma medications while on Doxiva?

It is generally safe to take other asthma medications while taking Doxiva. However, it is important to discuss this with your doctor before taking any other medicines, as they may interact with each other.

How long can I take Doxiva for?

The length of time you can take Doxiva for depends on your condition and response to treatment. It is important to follow your doctor’s instructions and not to stop taking the medication without their advice.

Can I take Doxiva while taking other medications?

It is important to tell your doctor about all other medications you are taking before starting on Doxiva. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

Can Doxiva cause nausea?

Yes, nausea is a potential side effect of taking Doxiva. If you experience any nausea, you should consult with your doctor. Your doctor may advise you to take the medicine with food or with an antacid.

What if I overdose on Doxiva?

If you overdose on Doxiva, seek medical help right away. Overdosing on this medicine may lead to serious side effects, such as difficulty breathing, chest pain, and irregular heartbeat.

Can Doxiva make my asthma symptoms worse?

It is important to speak to your doctor if you experience any worsening of your asthma symptoms while taking Doxiva. Your doctor may need to adjust your dosage or recommend a different medication.

Does Doxiva help with shortness of breath?

Yes, Doxiva is used to treat breathing difficulties associated with asthma and COPD, including shortness of breath. It works by relaxing the air passages and reducing the swelling of the lining of the airways.

Is Doxiva available over the counter?

No, Doxiva is not available over-the-counter. You must obtain this medicine through prescription from your doctor.

Should I take Doxiva in the morning or at night?

The timing of your dose of Doxiva is important and you should follow your doctor’s instructions regarding when to take the medicine. Generally, Doxiva is usually taken twice daily and should be taken with food.

Are there any safety precautions I should be aware of while taking Doxiva?

Yes, there are some safety precautions you should be aware of while taking Doxiva. These include avoiding alcohol, operating any heavy machinery or vehicles, and letting your doctor know if you have heart or kidney problems. Additionally, it is important to not take more than the recommended dosage of the medicine.