Doximar

Doximar Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Doximar is a brand name. Its generic name is Doxofylline.

Introduction

Doximar is an oral synthetic xanthine derivative used to treat and prevent wheezing or long-term breathing difficulty in people with asthma or other chronic pulmonary diseases such as COPD or emphysema. It is classified as a bronchodilator.

Uses for

Doximar’s primary use is to help to open the airways in the lungs as it works as a bronchodilator. It is used in conditions such as asthma, chronic obstructive pulmonary disease (COPD), bronchitis, emphysema, and chronic bronchitis. In addition, Doximar can also be used to treat nasal congestion, recurrent respiratory infections and difficulty in breathing during exercise.

Mechanism of Action

Doximar works mainly by opening up the airways in the lungs. It achieves this by inhibiting the chemicals that cause the airways to become constricted or narrow. This relaxes the muscles in the airways allowing them to open wider, which makes it easier for the air to flow in and out of the lungs. This helps to reduce symptoms of asthma and other breathing difficulties as well as reducing the frequency of asthma attacks.

How Long Does it Take to Work?

Doximar usually takes around 30 minutes to begin to take effect. The maximum effect is usually reached within one to four hours and the effects can last for up to six hours.

Absorption

Doximar is rapidly and completely absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 1-2 hours of administration.

Route of Elimination

Doximar is metabolised in the liver and is eliminated mainly by the kidneys. About 10-20% of the administered dose is excreted unchanged in the urine.

Dosage

The dosage of Doximar will depend on the individual. It is available as 50, 100 and 400 mg tablets and can be taken once or twice a day. It is recommended to take the lowest dose that is effective in controlling the condition. For adults, the usual starting dose is 100 mg twice a day and the maximum dose is 400 mg twice a day.Children aged 6 years and above should take 6-12 mg/kg/day in two to three divided doses.

Administration

Doximar should be taken exactly as your doctor has prescribed. It should be swallowed as a whole tablet with a glass of water and should not be crushed or chewed. The tablet should be taken before a meal or at bedtime.

Side Effect

The most common side effects of Doximar are headache, nausea, vomiting, abdominal pain, diarrhoea, and loss of appetite. Other side effects include dizziness, insomnia, dry mouth, and rash.

Toxicity

Doximar is not usually toxic in therapeutic doses, although an overdose of the drug may lead to serious side effects such as confusion, hallucinations, seizures, tachycardia, and respiratory depression. An overdose can be fatal if not treated immediately.

Precaution

Doximar should be taken with caution in patients with kidney or liver impairment. It should be used with caution in patients with diabetes, as it may cause a decrease in blood sugar levels. Patients should be advised to monitor blood sugar levels. Patients with a history of seizures should also use caution when taking this drug.

Interaction

Doximar can interact with certain medications, such as anticoagulants, oral contraceptives, and certain antibiotics. Alcohol can also interact with this drug and should be avoided. Patients should inform their doctor or pharmacist of all medications they are taking.

Disease Interaction

Doximar should be used with caution in patients with certain diseases as it may worsen symptoms or cause side effects. These include diabetes, kidney or liver impairment, heart failure, an overactive thyroid, and certain eye diseases.

Drug Interactions

Doximar can interact with certain drugs, including anticoagulants, diuretics, oral contraceptives, certain antibiotics, and other xanthine derivatives. Patients should inform their doctor or pharmacist of all medications they are taking.

Food Interactions

Food should be taken at least 2 hours (1 hour before or 1 hour after) after taking Doximar to decrease its effects. Patients should avoid caffeine-containing foods and drinks such as coffee, tea, and chocolate during the course of treatment.

Pregnancy Use

Doximar should be used with caution during pregnancy as it can cross the placenta and potentially cause harm to the fetus. It is not recommended for use during the first trimester of pregnancy.

Lactation Use

It is unknown whether Doximar is excreted in human breast milk. Therefore, caution should be exercised when administering this drug to nursing mothers.

Acute Overdose

An acute overdose of Doximar can lead to serious side effects such as confusion, hallucinations, seizures, tachycardia, and respiratory depression. Treatment of an overdose usually includes supportive care and symptomatic treatment.

Contraindication

Doximar is contraindicated in patients with known hypersensitivity to xanthine derivatives, as well as in patients with severe liver or kidney impairment.

Use Direction

Doximar should be taken as directed by the doctor or pharmacist. The tablets should be swallowed whole with a glass of water and should not be crushed or chewed. Take the drug at the same time every day and make sure to take the lowest dose that is effective in controlling the condition.

Storage Condition

Doximar should be stored at a controlled room temperature of 15 to 30°C and must be kept away from light, moisture and heat. The tablets must be stored in a locked container and should be out of reach of children.

Volume of Distribution

The volume of distribution of Doximar is approximately 0.6 L/kg. It is widely distributed into body tissues.

Half Life

The elimination half life of Doximar is approximately 3.3 hours although it may vary in different individuals.

Clearance

The total clearance of Doximar is approximately 17 mL/min/kg. The renal clearance is approximately 15 mL/min/kg.

Here you find in details version of Doximar

Some Frequently Asked Questions About Doximar

What is Doximar?

Doximar is a medicine used to treat breathing difficulties associated with asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing the air passages and reducing the swelling of the lining of the airways.

Is Doximar safe to take?

Yes, Doximar is generally considered safe to take and is used to treat breathing difficulties associated with asthma and COPD. However, it is important to discuss any potential risks or side effects with your doctor before taking this medicine.

How do I take Doximar?

Your doctor will provide you with instructions on how to take Doximar correctly. It is important to follow these instructions and take the medicine as directed. In general, Doximar is usually taken twice daily and should be taken with food.

What are the side effects of Doximar?

Common side effects of Doximar can include headache, nausea, stomach pain, and diarrhea. If you experience any severe or persistent side effects or if you have any questions regarding the medicine, contact your doctor as soon as possible.

Can I take Doximar if I'm pregnant?

It is not recommended to take Doximar if you are pregnant. If you become pregnant while taking this medicine, you should stop taking it and speak to your doctor right away.

What is the difference between Doximar and Theophylline?

Both Doximar and Theophylline are medicines used to treat breathing difficulties associated with asthma and COPD. Theophylline is a shorter-acting medicine than Doximar and is usually taken four times a day. Doximar is a longer-acting medicine and is typically taken twice a day.

Can I take other medications while taking Doximar?

It is important to tell your doctor about all other medications you are taking before starting on Doximar. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

Can I drink alcohol while taking Doximar?

It is generally not recommended to drink alcohol while taking Doximar. Alcohol can increase the risk of side effects and may also decrease the effectiveness of the medicine. If you have any questions or concerns, speak to your doctor.

How long does it take for Doximar to work?

It usually takes about 48 to 72 hours for Doximar to reach its full effect. If you have not noticed any improvement in your symptoms after this time, contact your doctor.

Is Doximar habit-forming?

No, Doximar is not considered to be habit-forming. However, it is important to take the medicine exactly as prescribed and not to take more than the recommended dosage.

What if I miss a dose of Doximar?

If you forget to take a dose of Doximar, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Does Doximar have any long-term side effects?

The long-term side effects of Doximar vary depending on the person and the length of time they have been taking it. It is important to speak to your doctor about any potential risks or side effects before taking this medicine.

Can Doximar cause headaches?

Yes, headaches are a common side effect of taking Doximar. If you experience any severe or persistent headaches, speak to your doctor.

Can Doximar make my breathing difficulties worse?

It is important to speak to your doctor if you experience any worsening of your breathing difficulties while taking Doximar. Your doctor may need to adjust your dosage or recommend another medication.

Do I have to take Doximar every day?

Yes, you should take Doximar as directed by your doctor in order to maintain the best possible result. It is important to take this medicine every day as it takes some time for the drug to reach its full effect.

What should I do if I have an allergic reaction to Doximar?

If you experience any allergic reactions to Doximar such as difficulty breathing, swelling of the face, lips, or tongue, or hives, stop taking the medicine immediately and seek medical help. Be sure to let your doctor know if you have had any allergic reactions to this medicine in the past.

When can I expect to see results while taking Doximar?

It typically takes about 48 to 72 hours for Doximar to reach its full effect. If you have not noticed any improvements in your symptoms after this time, you should discuss this with your doctor.

Can I take Doximar with other asthma medications?

It is generally safe to take Doximar with other asthma medications. However, it is important to discuss this with your doctor before taking any other medicines, as they may interact with each other.

Can Doximar help with difficulty breathing due to COPD?

Yes, Doximar is used to treat breathing difficulties associated with chronic obstructive pulmonary disease (COPD). It works by relaxing the air passages and reducing the swelling of the lining of the airways.

What should I do if I experience an irregular heartbeat while taking Doximar?

If you experience an irregular heartbeat or palpitations while taking Doximar, stop taking the medicine and seek medical help right away. Be sure to let your doctor know if you have had any heart problems in the past.

Does Doximar cause drowsiness?

Yes, drowsiness is a potential side effect of taking Doximar. If you experience any drowsiness, you should not operate any heavy machinery or vehicles.

Can I take Doximar while breastfeeding?

It is generally not recommended to take Doximar while breastfeeding. If you are breastfeeding and need to take this medicine, you should discuss this with your doctor.

What if I forget to take Doximar?

If you forget to take a dose of Doximar, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Can I take Doximar while pregnant?

It is not recommended to take Doximar if you are pregnant. If you become pregnant while taking this medicine, you should stop taking it and speak to your doctor right away.

Is it safe to take Doximar with other medications?

It is important to tell your doctor about all other medications you are taking before starting on Doximar. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

How much Doximar should I take?

Your dose of Doximar will depend on your medical condition and response to treatment. The dose may also be affected by other medications you are taking. You should always follow the instructions of your doctor and take the medicine exactly as directed.

What should I avoid while taking Doximar?

It is important to avoid alcohol while taking Doximar, as it may increase the risk of side effects and decrease the effectiveness of the medicine. Additionally, you should not operate any heavy machinery or vehicles, as the medicine may cause drowsiness.

Can I take Doximar without food?

It is generally recommended to take Doximar with food. Taking the medicine with food can help to reduce stomach upset and improve absorption of the drug. If you have any questions or concerns, speak to your doctor.

Does Doximar have any serious side effects?

Yes, there are potential serious side effects associated with the use of Doximar. These side effects can include shortness of breath, chest pain, irregular heartbeat, seizure, and rash. If you experience any of these symptoms, stop taking the medicine and seek medical help right away.

Can I take other asthma medications while on Doximar?

It is generally safe to take other asthma medications while taking Doximar. However, it is important to discuss this with your doctor before taking any other medicines, as they may interact with each other.

How long can I take Doximar for?

The length of time you can take Doximar for depends on your condition and response to treatment. It is important to follow your doctor’s instructions and not to stop taking the medication without their advice.

Can I take Doximar while taking other medications?

It is important to tell your doctor about all other medications you are taking before starting on Doximar. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

Can Doximar cause nausea?

Yes, nausea is a potential side effect of taking Doximar. If you experience any nausea, you should consult with your doctor. Your doctor may advise you to take the medicine with food or with an antacid.

What if I overdose on Doximar?

If you overdose on Doximar, seek medical help right away. Overdosing on this medicine may lead to serious side effects, such as difficulty breathing, chest pain, and irregular heartbeat.

Can Doximar make my asthma symptoms worse?

It is important to speak to your doctor if you experience any worsening of your asthma symptoms while taking Doximar. Your doctor may need to adjust your dosage or recommend a different medication.

Does Doximar help with shortness of breath?

Yes, Doximar is used to treat breathing difficulties associated with asthma and COPD, including shortness of breath. It works by relaxing the air passages and reducing the swelling of the lining of the airways.

Is Doximar available over the counter?

No, Doximar is not available over-the-counter. You must obtain this medicine through prescription from your doctor.

Should I take Doximar in the morning or at night?

The timing of your dose of Doximar is important and you should follow your doctor’s instructions regarding when to take the medicine. Generally, Doximar is usually taken twice daily and should be taken with food.

Are there any safety precautions I should be aware of while taking Doximar?

Yes, there are some safety precautions you should be aware of while taking Doximar. These include avoiding alcohol, operating any heavy machinery or vehicles, and letting your doctor know if you have heart or kidney problems. Additionally, it is important to not take more than the recommended dosage of the medicine.