Dilate Plus

Dilate Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dilate Plus is a brand name. Its generic name is Tropicamide + Phenylephrine Hydrochloride.

Introduction

Tropicamide and phenylephrine hydrochloride are two medications that are often prescribed together as a combination drug to treat certain eye problems. Tropicamide is an antispasmodic that helps to relax muscles, while phenylephrine hydrochloride is a decongestant that helps to reduce swelling in the eyes.

Uses

This combination drug is prescribed to treat a variety of eye conditions, such as prevention of cycloplegia during ophthalmoscopy, miosis, angle-closure glaucoma, and post-operative cystoid macular edema.

Mechanism of Action

Tropicamide helps to relax the ciliary muscle, which is a muscle that controls the shape of the lens in the eye. Once the muscle is relaxed, its contraction is limited, thus preventing cycloplegia from occurring. Phenylephrine hydrochloride is a decongestant that works by constricting blood vessels in the eye, reducing swelling.

How long does it take to work?

The effects of this drug are usually seen within 30 minutes of administration.

Absorption

Tropicamide is rapidly absorbed after topical administration and has a duration of action of several hours. The absorption of phenylephrine hydrochloride is not known.

Route of Elimination

Tropicamide is most likely eliminated by the kidneys and/or liver. The route of elimination of phenylephrine hydrochloride is not known.

Dosage

The recommended dosage of this drug is one to two drops of the combination into each affected eye twice daily. If you have an infection or inflammation of the eye, the dosage may need to be increased. If this is the case, it is important to speak with your doctor about the proper dosage.

Administration

This drug should be administered topically to the affected eye(s), and should never be taken orally or injected. When administering the medication, it is important to make sure that the tip of the dropper does not touch your eye, hands, or any other surface.

Side Effects

Some of the possible side effects of this drug include temporary blurred vision, burning or stinging in the eye, eye redness, dry eyes, and mild discomfort. If any of these side effects persist or worsen, it is important to contact your doctor.

Toxicity

The toxicity of this combination drug is low. However, if an overdose is suspected, it is important to seek medical attention immediately.

Precaution

This medication should not be used by anyone with a known allergy to either tropicamide or phenylephrine hydrochloride. It should also not be used by anyone with an active eye infection, glaucoma, or if you have recently had eye surgery.

Interactions

This drug may interact with other drugs, such as anticholinergics, sympathomimetics, and cholinergics. Before taking this medication, it is important to consult with your doctor or pharmacist about other medications you are taking.

Disease Interactions

This drug may be contraindicated in some diseases, such as narrow angle glaucoma, coronary insufficiency, or hypertension. It is important to speak with your doctor or pharmacist if you have any of these conditions before taking this drug.

Drug Interactions

This drug may interact with other drugs, such as anticholinergics, sympathomimetics, and cholinergics. Before taking this medication, it is important to consult with your doctor or pharmacist about other medications you are taking.

Food Interactions

This drug should not be taken with any food or beverage. It should be taken on an empty stomach.

Pregnancy Use

It is not known if this drug is safe for use during pregnancy. It is important to consult with your doctor before taking this medication if you are pregnant or planning to become pregnant.

Lactation Use

It is not known if this drug is safe for use while breastfeeding. It is important to consult with your doctor before taking this medication if you are breastfeeding.

Acute Overdose

Acute overdose of this drug may cause symptoms such as dizziness, blurred vision, headache, and seizures. If an overdose is suspected, it is important to seek medical attention immediately.

Contraindications

This drug should not be used by anyone with a known allergy to either tropicamide or phenylephrine hydrochloride. It should also not be used by anyone with an active eye infection, glaucoma, or if you have recently had eye surgery.

Use Directions

This drug should be administered topically to the affected eye(s), and should never be taken orally or injected. When administering the medication, it is important to make sure that the tip of the dropper does not touch your eye, hands, or any other surface.

Storage Conditions

This medication should be stored at room temperature in a dry and dark place away from direct sunlight.

Volume Of Distribution

The volume of distribution (Vd) of this drug is not known.

Half-Life

The half-life of this drug is not known.

Clearance

The clearance of this drug is not known.

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