Dextrim
Dextrim Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dextrim is a brand name. Its generic name is Dextromethorphan + Phenylephrine + Triprolidine.
Introduction
Dextromethorphan/Phenylephrine/Triprolidine (DPT) is a combination medication containing three active ingredients used to treat cold and flu symptoms. It is important to note that DPT is not an antibiotic and will not cure infections related to bacteria or viruses.Uses for
DPT is commonly used to treat the symptoms of the common cold or flu. It is also used to treat allergy symptoms, nasal congestion, and cough. It is often used in combination with other medications.Mechanism of Action
DPT works by suppressing the cough reflex and reduces inflammation. The dextromethorphan works as a cough suppressant, the phenylephrine acts as a decongestant and the triprolidine is a sedating antihistamine.How Long Does it Take to Work
DPT works quickly, typically providing relief from cold and flu symptoms within 30 minutes to an hour.Absorption
Dextromethorphan and phenylephrine are both rapidly absorbed through the gastrointestinal tract. Triprolidine is also well absorbed.Route of Elimination
All three active ingredient in DPT are eliminated via the kidney and liver.Dosage and Administration
DPT comes as a tablet, capsule, syrup, or liquid. The recommended dosage for adults is one or two tablets/capsules/syrups/liquid orally every 4 to 6 hours, up to a maximum of 8 tablets/capsules/syrups/liquid throughout the day, as needed for relief of symptoms. For children 6 to 12 years, the recommended dosage is ½ to 1 tablet/capsule/syrup/liquid every 4 to 6 hours, up to 4 dosages per day.Side Effects
The most common side effects of DPT are drowsiness, dry mouth, constipation, dizziness, nausea and vomiting. Other side effects may include agitation, confusion, abdominal pain, heartburn, difficulty urinating, and changes in blood pressure.Toxicity
Overdose of DPT can lead to symptoms such as difficulty breathing, seizures, extreme drowsiness, abnormal heartbeat, or loss of consciousness.Precautions
DPT should not be taken by individuals with severe kidneys or liver disease. It should also not be taken by those who recently had a heart attack or stroke or by pregnant women. Do not take for more than five days. DPT should not be taken with alcohol or certain other drugs.Interactions
DPT can interact with a variety of medications, including certain antibiotics, antidepressants, and drugs for pain or sleep. It can also interact with grapefruit and certain foods and beverages.Disease Interactions
DPT can interact with certain diseases or medical conditions, such as diabetes, hypertension, and chronic obstructive pulmonary disease.Drug Interactions
DPT should not be taken with certain medications. These include certain antibiotics, antidepressants, and drugs for pain or sleep.Food Interactions
DPT should be taken at least one hour after a meal and should not be taken with grapefruit or certain foods.Pregnancy Use
DPT is not recommended for use in pregnant women.Lactation Use
DPT is not recommended for use in breastfeeding women as it is not known to be safe.Acute Overdose
If an overdose of DPT is suspected, seek medical attention immediately. Symptoms of overdose may include difficulty breathing, seizures, extreme drowsiness, abnormal heartbeat, and loss of consciousness.Contraindication
DPT is contraindicated in individuals with severe kidney or liver disease, those who recently had a heart attack or stroke, and pregnant women.Use Direction
DPT should be taken orally as directed by a physician. If symptoms persist, individuals should contact their doctor.Storage Condition
DPT should be stored at room temperature and away from light, heat, and moisture.Volume of Distribution
DPT has a volume of distribution of 10.3 L/kg.Half-Life
DPT has a half-life of 1-2 hours.Clearance
DPT has a clearance of 16.5 L/hr/kg.Here you find in details version of Dextrim