Dextran 70

Dextran 70 Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dextran 70 is a brand name. Its generic name is Dextran + Sodium Chloride.

Introduction

Dextran and sodium chloride (otherwise known as “saline solution”) are a combination of ingredients used for a variety of medical purposes. They are typically used for intravenous (IV) solutions for hydration, electrolyte replenishment and to reduce swelling.

Uses

Dextran and sodium chloride are used for a variety of reasons in clinical practice. They can be used for:
  • treating dehydration
  • maintaining electrolyte balance
  • correcting electrolyte imbalances (especially hyponatremia and hypernatremia)
  • treating hypovolemia
  • treating edema caused by congestive heart failure
  • treating acid-base imbalances
  • preventing bacterial endocarditis
  • removing fluid from the body in cases of edema
  • treating overdose of barbiturates or opiates

Mechanism of Action

The combination of dextran and sodium chloride works by providing the body with the necessary amounts of sodium and other electrolytes. The dextran helps to reduce fluid loss by controlling the osmotic pressure of the solution and allowing water to move back into the cells. The sodium chloride in the solution is used to replenish electrolyte levels in the body.

How Long Does It Take to Work?

The length of time it takes for dextran and sodium chloride to work will depend on the type of situation being treated. In general, the solution should start to produce benefits within a few minutes of being administered.

Absorption

Dextran and sodium chloride are both readily absorbed by the body and can easily reach systemic circulation.

Route of Elimination

Dextran and sodium chloride are both eliminated from the body primarily through the kidneys.

Dosage

The dosage of dextran and sodium chloride will depend on the specific condition being treated and on the age, weight, and health of the patient. It is important to consult with a healthcare provider before taking any medication or supplement.

Administration

Dextran and sodium chloride are typically given intravenously via injection. It is important to follow the instructions of a healthcare provider when administering the solution.

Side Effects

Dextran and sodium chloride are generally well-tolerated, but side effects may occur. Possible side effects include nausea, vomiting, dizziness, headache, or rash. If any of these side effects occur, it is important to contact a healthcare provider for further evaluation and treatment.

Toxicity

Dextran and sodium chloride are generally very safe and non-toxic. These substances are not known to cause any serious or long-term damage when used as directed.

Precautions

Before taking dextran and sodium chloride, it is important to discuss any allergies or medical conditions with a healthcare provider. Additionally, people with diabetes or kidney disease should speak with their doctor before taking this solution.

Interactions

It is important to inform a healthcare provider of any other medications being taken before using dextran and sodium chloride. It is also important to let a healthcare provider know about any supplements, herbs, or vitamins being taken before using this solution.

Disease Interactions

Dextran and sodium chloride can interact with certain medical conditions. People with diabetes should be watched closely while taking this solution, as it may affect their blood sugar levels. People with kidney disease may need to have their electrolyte levels monitored more closely.

Drug Interactions

Dextran and sodium chloride can interact with certain medications, such as diuretics, angiotensin converting enzyme inhibitors, and non-steroidal anti-inflammatory drugs. It is important to notify a healthcare provider of all medications being taken before taking this solution.

Food Interactions

Dextran and sodium chloride do not usually interact with food. It is important to maintain a healthy and balanced diet while taking this solution.

Pregnancy Use

Dextran and sodium chloride should only be used during pregnancy if the potential benefits outweigh the potential risks. Women should consult with their healthcare provider before taking this solution.

Lactation Use

Dextran and sodium chloride should only be used during lactation if the potential benefits outweigh the potential risks. Women should consult with their healthcare provider before taking this solution.

Acute Overdose

Symptoms of an acute overdose of dextran and sodium chloride may include nausea, vomiting, dizziness, fatigue, and electrolyte imbalance. If any of these symptoms occur, it is important to seek medical attention immediately.

Contraindications

Dextran and sodium chloride should not be used in people with an allergy to either dextran or sodium chloride. It should also not be used in people with known electrolyte imbalances. It is important to discuss any potential contraindications with a healthcare provider before taking this solution.

Use Direction

The directions for using dextran and sodium chloride will depend on the specific condition being treated. It is important to follow the instructions of a healthcare provider when using this solution.

Storage Condition

Dextran and sodium chloride should be stored at room temperature in a cool, dry place. It should be kept out of direct sunlight and away from extreme temperatures.

Volume of Distribution

The volume of distribution of dextran and sodium chloride is relatively small, as it is mostly eliminated by the kidneys.

Half Life

The half life of dextran and sodium chloride is very short, as it is rapidly eliminated from the body.

Clearance

Dextran and sodium chloride are both eliminated primarily through the kidneys. The clearance of this solution is rapid and efficient.

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