Dexifen
Dexifen Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dexifen is a brand name. Its generic name is Dexibuprofen.
Introduction
Dexifen is a non-steroidal anti-inflammatory drug (NSAID), which is used for relief of pain and inflammation. It belongs to the class of drugs called COX-2 inhibitors, which reduces pain and inflammation. Dexifen was approved by the US FDA in July 2017.Uses
Dexifen is used to treat moderate to severe pain, inflammation and stiffness associated with arthritis and musculoskeletal conditions such as bursitis, tendinitis, and joint pain. It is also used to treat headaches, menstrual cramps, and other common pains.Mechanism of Action
Dexifen works by blocking the action of cyclooxygenase (COX), an enzyme involved in the production of substances called prostaglandins. Prostaglandins are responsible for causing inflammation, pain, and swelling. By blocking the enzyme, Dexifen blocks the production of these prostaglandins, thereby reducing the pain and inflammation caused by the affected condition.How long does it take to work?
The effects of Dexifen typically begin to take effect within 30 minutes to an hour after taking the drug. The drug may take up to 8 hours to show its full effects of relieving pain and inflammation.Absorption
Dexifen is rapidly and almost completely absorbed from the gastrointestinal tract. The peak serum levels of the drug occur approximately 1-2 hours after oral administration.Route of Elimination
Dexifen is metabolized in the liver and excreted in the urine and feces.Dosage
The typical recommended dosage of Dexifen is 400 to 800 mg per day, taken orally in divided doses (usually, twice a day). The dose may be increased or decreased based on the patient’s response to the medication.Administration
Dexifen is available in oral tablets and capsules, as well as in a liquid suspension. The tablets and capsules should be taken with a glass of water once or twice a day, as directed by the doctor. The liquid form of Dexifen should be taken with food or after meals.Side Effect
Some of the common side effects of Dexifen include nausea, vomiting, abdominal pain, indigestion, headache, dizziness, and diarrhea. Serious side effects such as bloody or black, tarry stools, chest pain, difficulty breathing, and weakness in the arms and legs have also been reported.Toxicity
High doses of Dexifen can lead to severe liver or kidney damage and even cause death. Regular monitoring of liver function tests is recommended in patients taking Dexifen. If any signs of liver or kidney damage appear, the dose of Dexifen should be reduced or stopped immediately.Precautions
Dexifen should be used with caution in patients with a history of asthma, stomach or intestinal ulcers, kidney or liver disease, bleeding disorders, or any other medical condition. It should not be used by pregnant women or those who are breastfeeding. People taking blood thinning medications should also avoid taking Dexifen.Interactions
Dexifen may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Dexifen.Disease Interaction
Dexifen may interact with certain diseases, such as asthma, gastrointestinal ulcers, kidney or liver disease, or any other medical condition. People with these diseases should use Dexifen with caution and monitor their condition closely.Drug Interactions
Dexifen may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Dexifen.Food Interactions
Dexifen may interact with certain foods, such as dairy products, alcohol, and spicy foods. It is best to avoid these foods while taking Dexifen to minimize any potential interactions.Pregnancy Use
Dexifen should be used with caution during pregnancy and should only be used if the potential benefits outweigh the risks to the baby. It is not recommended for pregnant women due to the potential for fetal damage or harm.Lactation Use
Dexifen should not be used while breastfeeding as it can pass into breast milk.Acute Overdose
An overdose of Dexifen can cause serious side effects, such as nausea, vomiting, abdominal pain, drowsiness, confusion, dizziness, fainting, respiratory depression, and death. If an overdose is suspected, seek medical attention immediately.Contraindication
Dexifen should not be used in patients with a known hypersensitivity to ibuprofen or other NSAIDs. Patients with a history of asthma, stomach or intestinal ulcers, bleeding disorders, kidney or liver disease, or any other medical condition should also avoid using Dexifen.Use Directions
Dexifen should be taken exactly as prescribed by the doctor. The tablets and capsules should be taken with a full glass of water once or twice a day, as directed. The liquid form of Dexifen should be taken with food or after meals.Storage Condition
Dexifen should be stored at room temperature away from direct light and moisture. Keep it away from pets, children, and any other medicines.Volume of Distribution
Dexifen has a volume of distribution of approximately 0.5 l/kg.Half Life
The half-life of Dexifen is approximately 2-3 hours.Clearance
The clearance rate of Dexifen is approximately 0.7 ml/min/kg.Here you find in details version of Dexifen
Some Frequently Asked Questions About Dexifen
What is Dexifen?
Dexifen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce symptoms of inflammation and pain.
What are the uses of Dexifen?
Dexifen is used to treat pain, inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and juvenile arthritis.
How should I take Dexifen?
Dexifen should be taken exactly as prescribed by your doctor. The usual adult dose is 200 to 400 mg every 4 to 6 hours.
Is Dexifen safe?
Yes, Dexifen is generally safe when taken as prescribed. However, like any medicine, there may be side effects or interactions with other medications.
Is Dexifen habit-forming?
No, Dexifen is not habit-forming and does not have any known abuse potential.
Are there any food or drink interactions with Dexifen?
Yes, Dexifen may interact with alcohol, caffeine, and certain foods. Therefore, it is important to check with your doctor or pharmacist before taking Dexifen.
What are the possible side effects of Dexifen?
Common side effects of Dexifen include abdominal pain, diarrhea, nausea, and headache. More serious side effects can occur, so it is important to talk to your doctor if you experience any unusual symptoms while taking Dexifen.
Does Dexifen have any interactions with other medications?
Yes, Dexifen may interact with some other medications, including aspirin, warfarin, and other NSAIDs. It is important to consult your doctor or pharmacist before taking any medications in combination with Dexifen.
What is the maximum daily dose of Dexifen?
The maximum daily dose of Dexifen is 800 mg per day for adults. For children, the maximum daily dose is determined based on age and weight.
What is the difference between Dexifen and ibuprofen?
Dexifen is a newer, long-acting version of ibuprofen, with a longer duration of action in the body. Dexifen is usually taken less frequently than ibuprofen, and is only available as a prescription medication.
Can pregnant or breastfeeding women take Dexifen?
It is not recommended for pregnant or breastfeeding women to take Dexifen. Women who are pregnant or breastfeeding should consult their doctor before taking any medication, including Dexifen.
Is Dexifen the same as aspirin or acetaminophen?
No, Dexifen is not the same as aspirin or acetaminophen. Dexifen is an NSAID, while aspirin and acetaminophen are not NSAIDs.
How does Dexifen work?
Dexifen works by blocking the production of certain chemicals in the body that cause inflammation and pain. This provides relief from the pain and inflammation associated with arthritis.
Can I take Dexifen with other medications?
It is not recommended to take Dexifen with certain other medications, such as aspirin, warfarin, or other NSAIDs. Consult your doctor or pharmacist before taking Dexifen with any other medication.
How long does it take for Dexifen to work?
It can take up to an hour for Dexifen to start relieving pain and inflammation. The effects of Dexifen can last for up to six hours.
In what form is Dexifen available?
Dexifen is available as a tablet, capsule, suspension, and injection. It is also available as an oral liquid for children.
How long does Dexifen take to leave the body?
The half-life of Dexifen is about 8 hours, so it takes an average of 24 to 36 hours for the drug to be completely eliminated from the body.
Can I buy Dexifen over-the-counter?
No, Dexifen is not available over the counter. It is only available by prescription from a doctor.
Is Dexifen addictive?
No, Dexifen is not an addictive drug and has no known abuse potential.
What happens if I take too much Dexifen?
Taking too much Dexifen can cause serious side effects like nausea, vomiting, stomach pain, drowsiness, headache, dizziness, or blurred vision. In some cases, it can even cause stomach or intestinal bleeding. If you take too much Dexifen, you should seek immediate medical attention.
Can I take Dexifen if I have liver or kidney problems?
It is not recommended for people with liver or kidney problems to take Dexifen. People with liver or kidney problems should consult their doctor before taking any medication.
Can Dexifen cause drowsiness?
Yes, Dexifen can cause drowsiness or dizziness in some people. It is important to check with your doctor before taking Dexifen if you are taking other medications that can cause drowsiness.
Does Dexifen interact with other substances?
Yes, Dexifen can interact with certain substances, such as alcohol, caffeine, and certain foods. It is important to discuss all medications and substances with your doctor before taking Dexifen.
How long can I take Dexifen safely?
It is not recommended to take Dexifen for longer than 10 days without consulting a doctor. Taking Dexifen for an extended period of time can increase the risk of serious side effects.
What should I do if I miss a dose of Dexifen?
If you miss a dose of Dexifen, take it as soon as you remember. Do not take two doses at once. If you take too much Dexifen, seek immediate medical attention.
Is Dexifen covered by insurance?
It depends. Most health insurance plans cover some or all of the cost of Dexifen. Check with your insurance provider for details on your coverage.
Are there any long-term side effects of taking Dexifen?
Long-term use of Dexifen can increase the risk of stomach or intestinal bleeding, heart attack, stroke, and kidney damage. If you are taking Dexifen for a prolonged period of time, it is important to talk to your doctor about the risks.
Does Dexifen affect blood pressure?
Yes, Dexifen can cause an increase in blood pressure. People with high blood pressure should consult their doctor before taking any medication, including Dexifen.
Can children take Dexifen?
Dexifen is approved for use in children as young as 2 years old. The dose and form of Dexifen used in children will be determined by the doctor and should be taken according to the doctor’s instructions.
Is Dexifen a steroid?
No, Dexifen is not a steroid. It is a nonsteroidal anti-inflammatory drug (NSAID).
What will happen if I stop taking Dexifen suddenly?
It is not recommended to stop taking Dexifen suddenly. If you need to stop taking Dexifen, talk to your doctor about how to do so safely.
Can I take Dexifen with food?
Yes, Dexifen can be taken with or without food. However, it is important to follow your doctor’s instructions and not take more than the recommended dose.
What other medications can I take with Dexifen?
It is important to talk to your doctor or pharmacist before taking any medications in combination with Dexifen, as some medications can interact with it. Some medications that are safe to take with Dexifen include acetaminophen, ibuprofen, and topical creams.
Can Dexifen be used for headaches?
Yes, Dexifen can be used for the temporary relief of headaches. If you experience frequent or severe headaches, it is important to talk to your doctor.
Does Dexifen help with swelling?
Yes, Dexifen is commonly used to reduce pain and swelling associated with conditions like osteoarthritis and rheumatoid arthritis.
Can I take Dexifen if I have a history of stomach ulcers?
It is not recommended for people with a history of stomach ulcers to take Dexifen. People with a history of stomach ulcers should talk to their doctor before taking any medication.
Can Dexifen help with menstrual cramps?
Yes, Dexifen can help to relieve pain associated with menstrual cramps. If menstrual cramps are severe or frequent, it is important to talk to a doctor.
Is Dexifen suitable for people with allergies?
Yes, Dexifen is suitable for people with allergies. People with allergies should check with their doctor before taking any medication, including Dexifen.
Can I take Dexifen with an antacid?
Yes, you can take Dexifen with an antacid. However, it is important to take antacids at least two hours before or after taking Dexifen to ensure maximum effectiveness.