Detrusin LA

Detrusin LA Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Detrusin LA is a brand name. Its generic name is Tolterodine.

Introduction

Detrusin LA is a medication used to treat bladder problems such as difficulty in urination. It works by blocking certain kinds of muscle contractions in the bladder, thus allowing more urine to be released. It can also decrease the number of urinary accidents caused by overactive bladder.

Uses For

Detrusin LA is used to treat bladder problems such as difficulty in urination, urinary frequency, and lack of control over urination (urge incontinence). It may also be used to reduce the number of urinary tract infections in people with an overactive bladder.

Mechanism of Action

Detrusin LA works by blocking the action of acetylcholine, which is a neurotransmitter that stimulates the bladder muscles. By blocking acetylcholine, tolterodine relaxes the bladder muscle, and this allows more urine to pass through.

How Long Does It Take To Work?

Detrusin LA usually begins to work in a few hours, but some people may not see the full effects for up to a week.

Absorption

Detrusin LA is well-absorbed after oral administration. The maximum concentrations of the active metabolite of tolterodine, 5-hydroxymethyl tolterodine, is reached about 2 hours after administration.

Route of Elimination

Detrusin LA and its active metabolite, 5-hydroxymethyl tolterodine are eliminated primarily through the urinary tract. Approximately 80% of the dose is excreted as either unchanged tolterodine or its active metabolite.

Dosage

The usual dose for adults is 2 mg twice daily with food. This can be adjusted depending on the individual’s response and tolerance to the medication. The maximum dose is 4 mg per day. Detrusin LA should not be used by children under the age of 18, and is not recommended for older adults.

Administration

Detrusin LA should be taken orally with food, and should be taken at the same time each day. It should be taken on a full stomach.

Side Effect

Common side effects of tolterodine include dry mouth, dizziness, and blurred vision. Other more serious side effects can include irregular heartbeat, weakness, and fainting.

Toxicity

Detrusin LA is usually well-tolerated, but it is possible for an overdose to occur. Symptoms of an overdose can include extreme drowsiness, slowed breathing, and coma. If an overdose is suspected, seek medical attention immediately.

Precautions

Detrusin LA should not be taken with other medications that contain anticholinergics, as this may increase the risk of side effects. Notify your doctor if you have any heart problems, or if you have a seizure disorder or a bladder obstruction, as tolterodine may not be suitable.

Interaction

Detrusin LA should not be taken with antacids, or with medications that contain anticholinergics. Tell your doctor about all other medications you are taking, as well as any supplements, herbal remedies or over-the-counter drugs.

Disease Interaction

Detrusin LA should not be taken if you suffer from certain liver diseases, or if you have glaucoma. If you suffer from any disease, it is important to inform your doctor before taking tolterodine.

Drug Interaction

Detrusin LA may interact with certain drugs, including antacids, other tolterodine products, and medications containing anticholinergics. It is important to let your doctor know of all the medications and supplements you are currently taking before starting tolterodine.

Food Interactions

Detrusin LA should be taken with food to help increase its absorption. Avoid taking tolterodine with alcohol or grapefruit juice, as this can cause side effects.

Pregnancy Use

Detrusin LA should not be used during pregnancy unless absolutely necessary. Speak with your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.

Lactation Use

It is not known if tolterodine passes into breast milk. If you are breastfeeding, speak with your doctor before taking tolterodine.

Acute Overdose

Signs of an overdose include extreme drowsiness, slowed breathing, and coma. Seek medical attention immediately if an overdose is suspected.

Contraindication

Detrusin LA should not be taken if you have certain liver diseases, glaucoma, or if you are taking antacids or other tolterodine products. It should also be avoided in children under the age of 18, and in patients over the age of 65.

Use Direction

Take tolterodine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Take it with food to help increase its absorption, and take it at the same time each day.

Storage Condition

Keep tolterodine in a sealed container at room temperature, away from moisture, heat, and light.

Volume of Distribution

The plasma volume of distribution of tolterodine is approximately 0.4L/kg.

Half Life

The half-life of tolterodine is 8 hours.

Clearance

The clearance of tolterodine is approximately 6.9 mL/min/kg.

Here you find in details version of Detrusin LA

Some Frequently Asked Questions About Detrusin LA

What is Detrusin LA?

Detrusin LA is a prescription medication used to treat symptoms of an overactive bladder, including the frequent urge to urinate, feeling the need to urinate frequently or urgently, and leaking of urine. It works by decreasing muscle spasms of the bladder.

What brand names are available for Detrusin LA?

Detrusin LA is available under the brand names Detrol, Detrol LA, and Uromax.

What is the most important information I should know about Detrusin LA?

Detrusin LA may cause drowsiness or blurred vision. If affected, do not drive or engage in activities that require alertness. Avoid drinking alcohol as this may increase the drowsiness and dizziness.

Is Detrusin LA safe to use during pregnancy?

There are no adequate studies done on Detrusin LA to determine its safety during pregnancy. Consult your doctor before taking this medication if you are pregnant or if you become pregnant while taking Detrusin LA.

What should I do if I forget a dose?

If you forget a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up the dose.

What are the side effects of Detrusin LA?

Common side effects of Detrusin LA include dry mouth, headache, fatigue, constipation, stomach upset, nausea, and dizziness. Seek medical attention if any of these side effects become severe.

Does Detrusin LA interact with other medications?

Detrusin LA may interact with some medications and supplements, especially antifungals, antibiotics, or antidepressants. Tell your doctor about all medications and supplements you are taking to avoid a drug interaction.

Can I take Detrusin LA if I have kidney disease?

Detrusin LA is not recommended in patients with severe kidney impairment. Your doctor will decide the best treatment option for you.

Can I take Detrusin LA with other bladder control medications?

Do not take other bladder control medications along with Detrusin LA. Consult your doctor if you are taking any bladder control medication.

Can I take Detrusin LA if I have glaucoma?

Detrusin LA may worsen glaucoma symptoms. Consult your doctor before taking Detrusin LA to determine if it is safe for you to take.

Is Detrusin LA safe for long-term use?

Detrusin LA is generally safe for long-term use when taken as recommended by your doctor. Consult your doctor if you have any questions or concerns about long-term use of Detrusin LA.

Does Detrusin LA cause weight gain?

Detrusin LA has not been shown to cause weight gain, but it is possible that certain side effects, such as fatigue and constipation, may lead to an increase in appetite and a subsequent weight gain.

Should I avoid certain foods while taking Detrusin LA?

Detrusin LA is not known to interact with specific foods, but you should talk to your doctor to determine which foods and beverages you should avoid while taking Detrusin LA.

Can I drink alcohol while taking Detrusin LA?

It is not recommended to drink alcohol while taking Detrusin LA as it may increase the side effects of the medication and decrease its effectiveness.

Should I take Detrusin LA on an empty stomach?

Detrusin LA can be taken with or without food. Taking it with food may reduce stomach upset.

Is Detrusin LA a controlled substance?

Detrusin LA is not a controlled substance. However, it is a prescription medication and should be used as directed by the prescribing doctor.

Does Detrusin LA cause insomnia?

Insomnia has not been reported as a common side effect of Detrusin LA. If you experience insomnia while taking Detrusin LA, contact your doctor.

Can I take other medications while taking Detrusin LA?

You should discuss all medications you are taking with your doctor before beginning Detrusin LA, to avoid potential interactions. Be sure to tell your doctor about any herbal supplements, non-prescription drugs, or any other medications you are taking.

Will Detrusin LA help with night-time urination?

Detrusin LA may help to reduce the frequency of night-time urination, but it is not intended to treat this symptom.

Should I stop taking Detrusin LA if I no longer experience bladder symptoms?

If your bladder symptoms have been resolved, you should still continue taking Detrusin LA as prescribed. If you are unclear about how long you should take Detrusin LA, consult your doctor.

Is Detrusin LA an anticholinergic medication?

Yes, Detrusin LA is an anticholinergic medication. Anticholinergic medications work by blocking certain nerve signals that cause muscle spasms or other involuntary movements.

What is the usual dosage of Detrusin LA?

The usual recommended dosage of Detrusin LA is 2 mg twice daily. However, your doctor will determine the best dosage for you based on your medical condition.

Can I take Detrusin LA with other types of medications?

Detrusin LA should not be taken with other medications that act on the bladder, such as oxybutynin and solifenacin. Discuss all medications you are taking with your doctor before beginning Detrusin LA.

If I am taking Detrusin LA, can I still go swimming?

Yes, you can still go swimming while taking Detrusin LA. However, you should keep in mind that Detrusin LA may cause side effects such as dizziness or drowsiness, and swimming in these conditions may pose a safety risk.

What should I do if I experience muscle spasms after taking Detrusin LA?

Muscle spasms can be a side effect of Detrusin LA. If you experience severe muscle spasms, contact your doctor as soon as possible.

What are the most common side effects of Detrusin LA?

The most common side effects of Detrusin LA are dry mouth, headache, fatigue, constipation, stomach upset, nausea, and dizziness. Consult your doctor if any of these side effects become severe or if they persist.

Can Detrusin LA cause difficulty urinating?

Detrusin LA is designed to reduce the frequency of urination and can sometimes cause difficulty urinating. If you experience difficulty urinating while taking Detrusin LA, contact your doctor.

Is Detrusin LA available as an over-the-counter medication?

No, Detrusin LA is not available as an over-the-counter medication. It is available as a prescription medication and should be taken as directed by your doctor.

Can I take Detrusin LA if I am breastfeeding?

It is not known if Detrusin LA passes into breastmilk. Therefore, it is recommended that you not take Detrusin LA if you are breastfeeding.

What should I do if I experience side effects from taking Detrusin LA?

If you experience any side effects while taking Detrusin LA, contact your doctor as soon as possible. Your doctor will determine if any further medical attention is required.

Can I take antacids while taking Detrusin LA?

It is not recommended to take antacids while taking Detrusin LA. Antacids may reduce the effectiveness of the medication. Consult your doctor for more information.

Can Detrusin LA cause blurred vision?

Blurred vision is a common side effect of Detrusin LA. If you experience blurred vision while taking Detrusin LA, contact your doctor.

Is Detrusin LA a narcotic medication?

No, Detrusin LA is not a narcotic medication. It is an anticholinergic medication used to treat symptoms of an overactive bladder.

Can Detrusin LA be taken with other anticholinergic medications?

No, Detrusin LA should not be taken with other anticholinergic medications. Consult your doctor for more information.

Does Detrusin LA interfere with my bladder control?

Detrusin LA is not known to interfere with bladder control. It is used to reduce the frequency of bladder muscle contractions, which can help to improve bladder control.

Can I take Detrusin LA if I have a catheter in place?

Yes, it is safe to take Detrusin LA if you have a catheter in place. However, you should talk to your doctor to ensure that it is safe for you to take.

Can Detrusin LA cause constipation?

Constipation is a common side effect of Detrusin LA. If you experience severe constipation while taking Detrusin LA, contact your doctor as soon as possible.

What should I do if I experience severe dry mouth while taking Detrusin LA?

Dry mouth is a common side effect of Detrusin LA, but if it becomes severe or uncomfortable, contact your doctor as soon as possible. Your doctor may recommend a saliva substitute or other measure to help manage your dry mouth.

Can I take Detrusin LA while taking diuretics?

Yes, it is safe to take Detrusin LA while taking diuretics. However, you should talk to your doctor to ensure that it is safe for you to take both medications.

Can I take Detrusin LA if I have diabetes?

Yes, it is safe to take Detrusin LA if you have diabetes. However, your doctor may need to adjust the dosage of insulin or other diabetes medications while taking Detrusin LA.

Can I take Detrusin LA while taking antibiotics?

Yes, it is safe to take Detrusin LA while taking antibiotics. However, you should talk to your doctor to ensure that it is safe for you to take both medications.

Can I take Detrusin LA while taking antifungal medications?

No, it is not recommended to take Detrusin LA while taking antifungal medications due to potential drug interactions. Talk to your doctor about other treatment options for your condition.

Can I take Detrusin LA while taking blood pressure medications?

Yes, it is safe to take Detrusin LA while taking blood pressure medications. However, you should talk to your doctor to ensure that it is safe for you to take both medications.

Can I take Detrusin LA while taking antidepressant medications?

No, it is not recommended to take Detrusin LA while taking antidepressant medications due to potential drug interactions. Talk to your doctor about other treatment options for your condition.