Desyeno Er

Desyeno Er, a brand name for a formulation containing essential Desvenlafaxine, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Desyeno Er, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.

Introduction

Desyeno Er, also known by its brand name Pristiq, is an antidepressant medication used to treat major depressive disorder (MDD). It is a serotonin-norepinephrine reuptake inhibitor (SNRI). It belongs to the same class of medications as venlafaxine (Effexor) and duloxetine (Cymbalta).

Uses For

Desyeno Er is used to treat adults with major depressive disorder (MDD). It is also used to treat generalized anxiety disorder (GAD), panic disorder, post-traumatic stress disorder (PTSD), and social anxiety disorder.

Mechanism of Action

The exact mechanism of action of desvenlafaxine is not known. It is thought to work by increasing the amount of serotonin and norepinephrine in the brain, which are two neurotransmitters that are associated with feelings of wellbeing and mood balance.

How Long Does It Take to Work?

Desyeno Er usually starts to work within one to three weeks. It can take six weeks or longer before its full effects are felt. The response to treatment may vary from patient to patient.

Absorption

Desyeno Er is rapidly absorbed after oral administration with peak concentrations occurring within 1-2 hours. It is highly bioavailable with an absolute oral bioavailability of approximately 70%.

Route of Elimination

Desyeno Er is primarily metabolized in the liver by the cytochrome P450 isoenzyme CYP2D6 and to a lesser extent by CYP2C19 and CYP3A4. It is eliminated by the kidneys in unchanged form and as metabolites.

Dosage

Desyeno Er is available as an extended-release tablet taken by mouth once daily. The usual starting dose is 50 mg once daily. This drug may be increased up to 100 mg daily, depending on the patient’s response.

Administration

Desyeno Er should be taken by mouth once daily with or without food. The tablet can be swallowed whole or dissolved in water to form a suspension for easier ingestion if needed.

Side Effect

Desyeno Er may cause side effects such as nausea, vomiting, constipation, dry mouth, insomnia, headache, dizziness, and drowsiness. If these side effects do not go away or become bothersome, contact your doctor for advice.

Toxicity

Desyeno Er has low toxicity and is unlikely to cause serious adverse effects. Severe to life-threatening reactions have been reported but typically only occur in the setting of overdose.

Precaution

Patients should be monitored for underlying medical conditions, particularly depression and suicidal thoughts. Patients should be monitored for changes in behavior, especially during the first few months of treatment.

Interaction

Desyeno Er can interact with certain medications (e.g. antidepressants, heart medications, blood thinners, etc.). It can also interact with certain foods and beverages (e.g. alcohol, grapefruit juice, etc.). Patients should discuss all potential drug and food interactions with their doctor prior to taking desvenlafaxine.

Disease Interaction

Desyeno Er may interact with certain diseases, such as bipolar disorder, glaucoma, liver disease, and kidney disease. Patients should discuss any known disease interactions with their doctor prior to taking desvenlafaxine.

Drug Interaction

Desyeno Er may interact with certain drugs, such as non-steroidal anti-inflammatory drugs (NSAIDs), anticoagulants, and antiarrhythmics. Patients should discuss all potential drug interactions with their doctor prior to taking desvenlafaxine.

Food Interaction

Desyeno Er may interact with certain foods and beverages, such as alcohol, grapefruit juice, and caffeine. Patients should discuss all potential food and beverage interactions with their doctor prior to taking desvenlafaxine.

Pregnancy Use

Desyeno Er should be used in pregnancy only when the benefit outweighs the risk. Patients should discuss all concerns with their doctor prior to taking desvenlafaxine.

Lactation Use

Desyeno Er is excreted in breast milk and should be avoided in nursing mothers. Patients should discuss all concerns with their doctor prior to taking desvenlafaxine.

Acute Overdose

Acute overdose of desvenlafaxine can be life-threatening. Symptoms of overdose may include somnolence, confusion, coma, and seizures. If an acute overdose is suspected, immediate medical attention should be sought.

Contraindication

Desyeno Er is contraindicated in patients with hypersensitivity to the drug or any of its components. It is also contraindicated in patients with certain underlying medical conditions, such as bipolar disorder, glaucoma, liver disease, and kidney disease.

Use Direction

Desyeno Er should be taken as directed by your doctor. The usual dose is 50-100 mg taken orally once daily with or without food. Do not take more than the recommended dose.

Storage Condition

Desyeno Er should be stored at room temperature, away from moisture and heat. Do not store in the bathroom. Keep this and all medication out of the reach of children.

Volume of Distribution

The volume of distribution of desvenlafaxine is approximately 42 liters/kg.

Half Life

The elimination half-life of desvenlafaxine is approximately 11 hours.

Clearance

The clearance of desvenlafaxine is approximately 0.95 mL/min/kg.

Here you find in details version of Desyeno Er

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