Delorin

Delorin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Delorin is a brand name. Its generic name is Desloratadine.

Introduction

Delorin is an antihistamine developed by the German pharmaceutical company Schering. It is used to treat hay fever, urticaria, and other allergic symptoms. It is commonly used for both allergic and non-allergic rhinitis, as well as conjunctivitis due to allergies.

Uses For

Delorin is used in adults and children aged 12 years or above to relieve the symptoms of hay fever (allergic rhinitis) and hives (urticaria).

Mechanism of Action

Delorin works by blocking the action of histamine. Histamine is one of the chemicals released by the body during an allergic reaction. By blocking histamine, desloratadine reduces the swollen, red, itchy skin associated with hives and the runny nose and headache symptoms of hay fever and other allergies.

How Long Does it Take to Work?

Delorin generally begins to work within one to three hours after taking the medication.

Absorption

Delorin is absorbed quickly and completely after oral administration.

Route of Elimination

Delorin is metabolized in the liver and eliminated through the urine.

Dosage

Delorin is available in several forms: 0.5 mg, 1 mg, 2.5 mg, 5 mg, and 10 mg tablets, a 0.5 mg/mL syrup, and 5 mg and 10 mg dispersed tablets in sachet. The recommended dosage for adults and children aged 12 and older is 5 mg once daily.

Administration

Delorin should be taken orally with water. Tablets should not be chewed or crushed. The tablets and syrup may be taken with or without food.

Side Effects

Common side effects of desloratadine include headache, dry mouth, nosebleeds, and sore throat. Rarely, some people may experience serious side effects such as anaphylaxis, heart palpitations, and seizures.

Toxicity

Delorin is generally safe and well tolerated, and overdoses are not life-threatening. Symptoms of an overdose may include drowsiness, dizziness, dry mouth, and upset stomach.

Precautions

Delorin should be used with caution in people with liver and kidney diseases, as reduced renal and hepatic function can reduce its efficacy. In addition, it should not be taken by people who are taking other drugs that may interact with it, such as ketoconazole, itraconazole, or certain antibiotics.

Interaction

Delorin may interact with other drugs, including antacids, anticoagulants, antipsychotics, certain antibiotics, and digoxin.

Disease Interaction

Delorin may interact with certain diseases such as asthma, kidney disease, and liver disease.

Drug Interaction

Delorin may interact with drugs such as ketoconazole, itraconazole, and certain antibiotics. Other interactions can occur, so patients should always inform their healthcare provider of any medications they are taking.

Food Interactions

No clinically significant food interactions have been reported with the use of desloratadine.

Pregnancy Use

Delorin is not recommended for use during pregnancy.

Lactation Use

It is not known if desloratadine is safe for use in lactating women. It should be used with caution if breastfeeding.

Acute Overdose

Symptoms of an overdose may include drowsiness, dizziness, dry mouth, and upset stomach. If an overdose occurs, it should be treated symptomatically and supportive measures should be taken.

Contraindication

Delorin is contraindicated in people who are hypersensitive to it or any of its ingredients.

Use Direction

Delorin should be taken orally with water, with or without food. Tablets should not be chewed or crushed. The recommended dosage for adults and children aged 12 and older is 5 mg once daily.

Storage Condition

Delorin should be stored at room temperature between 68°F and 77°F (20°C and 25°C). Keep this and all other medications away from children and pets.

Volume of Distribution

The apparent volume of distribution of desloratadine is approximately 17 L/kg.

Half Life

The half-life of desloratadine is approximately 24 hours.

Clearance

The overall clearance of desloratadine is approximately 3 mL/min/kg.

Here you find in details version of Delorin

Some Frequently Asked Questions About Delorin

What is desloratadine?

Delorin is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

Can I take desloratadine while pregnant?

Delorin has not been studied in pregnant women, so talk to your doctor if you are pregnant or plan on becoming pregnant before taking desloratadine.

Is desloratadine a steroid?

No, desloratadine is not a steroid. Delorin is an antihistamine.

Can desloratadine cause drowsiness?

Yes, desloratadine can cause drowsiness. If you experience drowsiness while taking desloratadine, do not operate heavy machinery or drive a car until you are sure the drug does not affect you adversely.

What are the side effects of desloratadine?

The most common side effects of desloratadine are headache, drowsiness, dry mouth, sore throat, and cough. Other less common side effects include nausea, vomiting, dizziness, constipation, fatigue, and difficulty sleeping.

How should desloratadine be stored?

Delorin should be stored at room temperature (15-30°C/59-86°F), away from moisture and heat. Keep the medication in a secure container out of reach of children.

How long does desloratadine take to work?

Delorin usually starts to work within 1 to 3 hours after taking it. The effects may last up to 24 hours.

Is desloratadine an over the counter medicine?

Yes, desloratadine is available over the counter and does not require a prescription.

How long can you take desloratadine for?

Delorin should be taken for the shortest amount of time necessary to relieve symptoms. Do not take desloratadine for longer than 2 weeks without consulting your doctor.

What is the difference between desloratadine and loratadine?

Delorin and loratadine are both antihistamines used to relieve allergy symptoms. Delorin may be more effective at relieving symptoms than loratadine and can last longer in the body.

Is desloratadine a brand name or generic?

Delorin is both a brand name and a generic drug. It is available under several brand names including Clarinex and NeoClarityn.

What is desloratadine used for?

Delorin is used to treat allergies and the symptoms that result from them such as sneezing, runny nose, itching eyes, and itchy or watery eyes.

What is desloratadine 5 mg used for?

Delorin 5 mg is used to relieve allergy symptoms such as sneezing, runny nose, itchy/watery eyes, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

Does desloratadine help with post nasal drip?

Yes, desloratadine can help relieve post-nasal drip by blocking the release of histamine which helps to reduce inflammation and mucus production.

Will desloratadine help a sinus headache?

Yes, desloratadine can help reduce a sinus headache by blocking the release of histamine, which helps reduce inflammation, pressure and nasal congestion.

Can I take desloratadine with alcohol?

No, you should not take desloratadine with alcohol as it can increase the side effects such as drowsiness, confusion, and dizziness.

Are there any drug interactions with desloratadine?

Yes, there are possible drug interactions with desloratadine. It is important to talk to your doctor and pharmacist before taking any other medications while taking desloratadine.

Is desloratadine safe for long term use?

Delorin is generally safe for short-term use but may not be suitable for long-term use as it can cause the body to become immune to its effects or cause other side effects.

How much desloratadine can I take?

The recommended dose of desloratadine for adults is 5 mg once daily. For children aged 2-11, the recommended dose is 2.5 mg once daily.

Does desloratadine have anti-inflammatory properties?

No, desloratadine does not have anti-inflammatory properties. Delorin is an antihistamine which blocks the release of histamine, a chemical that is responsible for allergy symptoms.

Can desloratadine be used for hives?

Yes, desloratadine can be used to treat hives. Delorin works by blocking the release of histamine, a chemical responsible for allergy symptoms such as hives.

Can desloratadine cause insomnia?

Delorin may cause difficulty sleeping in some people. If you are experiencing insomnia while taking desloratadine, talk to your doctor as they may need to adjust your dose or switch you to a different medication.

Can desloratadine cause dry mouth?

Yes, desloratadine can cause dry mouth. If you are experiencing dry mouth while taking desloratadine, it is important to drink plenty of fluids and practice good oral hygiene to help reduce the symptoms.

Can desloratadine make you dizzy?

Yes, desloratadine can make you feel dizzy or lightheaded. If you experience dizziness while taking desloratadine, talk to your doctor as they may need to switch you to a different medication.

Does desloratadine have antihistamine potential?

Yes, desloratadine is an antihistamine and works by blocking the release of histamine, a chemical responsible for allergy symptoms.

Can desloratadine be used for seasonal allergies?

Yes, desloratadine can be used to treat seasonal allergies. Delorin works by blocking the release of histamine, a chemical responsible for allergy symptoms.

Can desloratadine be used for allergic rhinitis?

Yes, desloratadine can be used for the treatment of allergic rhinitis. Delorin works by blocking the release of histamine, a chemical responsible for allergy symptoms.

Can I take Claritin and desloratadine together?

No, you should not take Claritin and desloratadine together as they both contain the same active ingredient (loratadine) which could increase the risk of side effects.

Can desloratadine cause weight gain?

Weight gain is not listed as a common side effect of desloratadine. If you experience weight gain while taking desloratadine, talk to your doctor.

Can desloratadine cause high blood pressure?

No, desloratadine does not usually cause high blood pressure. If you have high blood pressure, talk to your doctor before taking desloratadine.

Is desloratadine safe for children?

Yes, desloratadine is safe for children over the age of 2. It is important to follow your doctor's instructions for dosing and administration.

Can desloratadine cause headaches?

Yes, desloratadine can cause headaches in some people. Talk to your doctor if you experience frequent or severe headaches while taking desloratadine.

Does desloratadine have anti-allergy properties?

Yes, desloratadine is an antihistamine which works to block the release of histamine, a chemical responsible for allergy symptoms.

Can desloratadine make you sleepy?

Yes, desloratadine can make you feel drowsy or sleepy. If you experience drowsiness while taking desloratadine, do not operate machinery or drive until you are sure the drug does not affect you adversely.

Is desloratadine safe for dogs?

Delorin is not approved for use in animals and should not be given to dogs. It is important to talk to your veterinarian about the best treatment options for your dog.

Does desloratadine reduce swelling?

No, desloratadine does not reduce swelling. Delorin is an antihistamine which works to block the release of histamine, a chemical responsible for allergy symptoms.

What is the maximum dose of desloratadine?

The maximum recommended dose of desloratadine for adults and children 12 years or older is 10 mg per day. For children aged 2-11, the maximum recommended dose is 5 mg per day.

Can desloratadine be used for itching?

Yes, desloratadine can be used to treat itching. Delorin works by blocking the release of histamine, a chemical that is responsible for allergy symptoms such as itching.

Can desloratadine cause anxiety?

Anxiety is not a common side effect of desloratadine. If you experience anxiety while taking desloratadine, talk to your doctor as they may need to switch you to a different medication.

Can desloratadine cause confusion?

Yes, desloratadine can cause confusion in some people. If you experience confusion or disorientation while taking desloratadine, talk to your doctor as they may need to switch you to a different medication.

Does desloratadine have any interactions with other drugs?

Yes, desloratadine can interact with certain drugs. It is important to talk to your doctor and pharmacist before taking any other medications while taking desloratadine.

Can I take desloratadine with ibuprofen?

Yes, you can take desloratadine with ibuprofen, however, it is important to talk to your doctor and pharmacist before taking any other medications while taking desloratadine.

Can desloratadine cause constipation?

Yes, constipation is a possible side effect of desloratadine. If you are experiencing constipation while taking desloratadine, talk to your doctor as they may need to switch you to a different medication.

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