Delagil
Delagil Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Delagil is a brand name. Its generic name is Chloroquine.
Introduction
Delagil is an antimalarial medication used to prevent and treat malaria. It belongs to a group of medications known as synthetic antimalarials. It works by interfering with the growth of parasites in the red blood cells of the human body.Uses For
Delagil is usually used to prevent and treat malaria. It may also be used to treat infections caused by certain other parasites.Mechanism of Action
Delagil works by interfering with the growth of parasites in the red blood cells of the human body. It is thought that chloroquine works by inhibiting certain enzymes that are important for the survival of the parasite.How Long Does it Take to Work?
The effects of chloroquine in the treatment of malaria can be seen within 7 days of starting treatment.Absorption
Delagil is rapidly absorbed from the gastrointestinal tract. It is rapidly distributed to most organs and tissues, with concentrations being highest in the liver, lungs, and spleen.Route of Elimination
Delagil is mainly eliminated by the kidney. It is also metabolized in the liver and excreted in bile.Dosage
The recommended adult dose for prevention malaria is 500 mg of chloroquine phosphate once a week or 250 mg twice a week. For treating malaria in adults, the recommended dose is 500 mg of chloroquine phosphate once daily for two days followed by 500 mg once weekly for 8 weeks. Pediatric doses may need to be adjusted according to weight and body surface area.Administration
Delagil is usually taken orally with a full glass of water. It can be taken with or without food, but it is best to take it with food if stomach upset occurs. If you are taking chloroquine to prevent malaria, you should begin taking it at least 2 weeks before entering an endemic area. You should also continue taking it for 4 weeks after leaving the endemic area.Side Effect
Delagil may cause side effects such as nausea, vomiting, loss of appetite, headache, stomach pain, dizziness, and rash. Serious side effects include vision changes, seizures, irregular heartbeat, mental/mood changes, and anemia.Toxicity
Delagil can be toxic if too much of it is taken. Symptoms of chloroquine toxicity include nausea, vomiting, abdominal pain, dizziness, confusion, blurred vision, and seizures. In severe cases, coma and even death can occur.Precaution
It is important to tell your doctor about any other medications that you are taking before taking chloroquine. You should also tell your doctor if you have any allergies, history of eye problems, or if you have any liver or kidney problems.Interaction
Delagil can interact with certain medications such as magnesium oxide, ketoconazole, and tamoxifen. It can also interact with certain supplements such as vitamin C, calcium, and fluoride.Disease Interaction
Delagil can interact with certain medical conditions such as kidney disease, psoriasis, psoriatic arthritis, and sulfonamide sensitivity. People with these conditions should talk to their doctor before taking chloroquine.Drug Interaction
Delagil can interact with other medications such as phenytoin, pyrimethamine, warfarin, or other antimalarial medications.Food Interactions
Delagil may interact with certain foods such as alcohol, grapefruit juice, and horseradish.Pregnancy Use
Delagil should not be used during pregnancy unless the benefits outweigh the risks. If you are pregnant, talk to your doctor about the potential risks and benefits of using chloroquine.Lactation Use
It is not known whether chloroquine is excreted into human milk. Therefore, chloroquine should be used with caution in nursing women.Acute Overdose
If an overdose of chloroquine occurs, it is important to seek medical attention immediately. Symptoms of an overdose may include nausea, vomiting, abdominal pain, confusion, blurred vision, seizures, and coma.Contraindication
Delagil is contraindicated in patients with a known hypersensitivity to it.Use Direction
Follow the directions on your prescription label carefully. Do not take more than the recommended dose of chloroquine. Talk to your doctor or healthcare provider if you have any questions.Storage Conditions
Delagil should be stored at room temperature away from heat, light, and moisture.Volume of Distribution
Delagil is highly bound to plasma proteins, as well as red blood cells. The volume of distribution is 12-17L/kg.Half-Life
The terminal half-life of chloroquine is between 50 and 60 hours.Clearance
The renal clearance of chloroquine is 12-17ml/min/kg.Here you find in details version of Delagil
Some Frequently Asked Questions About Delagil
What is Delagil?
Delagil, also known as chloroquine phosphate, is an antimalarial medication used to treat and prevent malaria. It is also used to treat certain types of bacterial and protozoal infections.
How does Delagil work?
Delagil works by binding to protozoal cells and inhibiting the formation of heme, the component of hemoglobin that captures and transports oxygen.
What is Delagil used for?
Delagil is mainly used to treat and prevent malaria. It can also be used to treat certain protozoal infections, such as amebiasis and giardiasis.
What is Delagil phosphate?
Delagil phosphate is an antimalarial medication used to treat and prevent malaria. It is a chloroquine derivative.
What is the brand name for Delagil?
Delagil is a generic medication, but it is sold under brand names such as Aralen, Nivaquine, and Maprotiline.
What is the dosage for Delagil?
The recommended adult dose is 250 mg (4 tablets) once a week, taken together with proguanil, or 500 mg (8 tablets) once a week, taken without proguanil.
What are the side effects of Delagil?
Common side effects of chloroquine include headaches, loss of appetite, diarrhea, nausea, vomiting, and skin rash. Rarely, chloroquine can cause serious side effects, such as seizures and liver damage.
Is Delagil a vesicant?
No, chloroquine is not a vesicant.
Can Delagil be used to treat Covid-19?
Yes, chloroquine can be used to treat Covid-19 in combination with other medications, but only under the supervision of a doctor.
Is Delagil safe during pregnancy?
Delagil is not recommended for use during pregnancy, as it may harm the developing baby. Women who are pregnant or breastfeeding should discuss the risks and benefits of using chloroquine with their doctor.
Can Delagil be used to treat bacterial infections?
Yes, chloroquine can be used to treat certain bacterial infections, such as amebiasis and giardiasis.
Can Delagil be taken with other medications?
Yes, chloroquine can be taken with other medications, but patients should discuss the risks and benefits of taking multiple medications with their doctor.
What are the interactions of Delagil with other medications?
Delagil can interact with certain medications, including but not limited to: antacids, cimetidine, kaolin, aspirin, antihistamines, aminoglycosides, nonsteroidal anti-inflammatory drugs (NSAIDs), and tetracyclines.
What are the possible drug interactions of Delagil?
Delagil can interact with certain medications, including but not limited to antacids, cimetidine, kaolin, aspirin, antihistamines, aminoglycosides, nonsteroidal anti-inflammatory drugs (NSAIDs), and tetracyclines.
Is Delagil safe for children?
Delagil is generally safe for children, but children under 2 years of age should not take chloroquine. Children aged 2 to 16 years should take the adult dosage, but it should be divided into two doses, taken 12 hours apart.
Is Delagil available over the counter?
No, chloroquine is not available over the counter and it should only be taken under the supervision of a doctor.
Is Delagil addictive?
No, chloroquine is not known to be addictive.
How long does it take for Delagil to work?
It can take up to seven days for chloroquine to take full effect against malaria, but it usually works within two days.
What is the shelf life of Delagil?
The shelf life of chloroquine is three years.
Can Delagil be given intravenously?
Yes, chloroquine can be given intravenously, but it should only be done so under the supervision of a doctor.
Does Delagil cause hair loss?
Delagil can cause hair loss, but this is a rare side effect.
Is Delagil a blood thinner?
No, chloroquine is not a blood thinner.
How long does Delagil stay in your system?
Delagil can remain in the body for up to six weeks after it has been taken.
Can Delagil cure malaria?
Yes, chloroquine can be used to treat and prevent malaria.
Can Delagil be used to treat lupus?
Yes, chloroquine can be used to treat certain types of lupus.
Is Delagil only available in tablet form?
No, chloroquine is available in tablet and liquid form.
Does Delagil have any interactions with food?
Yes, chloroquine can interact with certain foods, such as dairy products, so it is important to discuss food interactions with your doctor before taking chloroquine.
Can Delagil cause kidney damage?
Delagil can rarely cause kidney damage, but it is important to discuss the risks of kidney damage with your doctor before taking chloroquine.
What are the long-term effects of taking Delagil?
Delagil can have long-term effects on the liver, kidneys, and vision. Rarely, choloroquine can cause irreversible damage to the eyes.
Is Delagil fatal?
Delagil can rarely cause death, but it is important to discuss the risks of taking chloroquine with your doctor before taking it.
What is the maximum dosage for Delagil?
The maximum recommended dosage of chloroquine is 500 mg per day.
Can Delagil cause an allergic reaction?
Yes, chloroquine can cause an allergic reaction, including difficulty breathing, hives, and swelling of the face, mouth, lips, tongue, or throat.
What does Delagil do to the retina?
Delagil can cause retinopathy, which is a condition that affects the retina of the eye. Prolonged use of chloroquine can cause permanent damage to the retina.
Can Delagil worsen existing liver disease?
Yes, chloroquine can worsen existing liver disease, so it is important to discuss the risks of taking chloroquine with your doctor before taking it.
Can Delagil cause liver damage?
Rarely, chloroquine can cause liver damage. It is important to discuss the risks of liver damage with your doctor before taking chloroquine.
Can Delagil be used to treat ringworm?
Yes, chloroquine can be used to treat certain types of fungal infections, including ringworm.
Can Delagil cause dizziness?
Yes, chloroquine can cause dizziness, but it is usually temporary.
Can Delagil be used to treat urinary tract infections?
No, chloroquine cannot be used to treat urinary tract infections.
Can Delagil cause nausea?
Yes, chloroquine can cause nausea, but this is usually temporary.
Can Delagil cause diarrhea?
Yes, chloroquine can cause diarrhea, but this is usually temporary.
Can Delagil cause stomach pain?
Yes, chloroquine can cause stomach pain, but this is usually temporary.
Can Delagil be used to treat chlamydia?
No, chloroquine cannot be used to treat chlamydia.
Can Delagil cause liver failure?
Rarely, chloroquine can cause liver failure. It is important to discuss the risks of taking chloroquine with your doctor before taking it.