Cyred

Cyred, a brand name for a formulation containing essential Ethinyl Estradiol + Desogestrel, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Cyred, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.

Introduction

Cyred is a combination oral contraceptive pill (OCP) commonly used as a form of birth control. The combination contains a synthetic estrogen compound (ethinyl estradiol) and a progestin compound (desogestrel) that work together against pregnancy by inhibiting ovulation, creating a fertilization-resistant environment in the cervix, and thickening cervical mucus.

Uses

Cyred is primarily used to prevent pregnancy. Additionally, it can help lighten menstrual flow, lessen dysmenorrhea, reduce acne, and reduce risk of pelvic inflammatory diseases. It can also help to reduce symptoms of pre-existing endometriosis and reduce ovarian cysts.

Mechanism of Action

Cyred works primarily by suppressing the body's natural reproductive cycle. The combination blocks ovulation, making it harder for a mature egg to be fertilized. Additionally, it causes thinning and stickiness of cervical mucus, making it more difficult for sperm to pass through the cervix. It also alters uterine walls, making implantation of a fertilized egg more difficult.

How Long Does it Take to Work?

Cyred begins working on the first day when taken as directed. It is important to start the OCP on the Sunday following the start of a menstrual period.

Absorption

Cyred is quickly and completely absorbed in the body following oral administration. Peak concentrations of both hormones occurs shortly after ingestion, however the two hormones have different half-lives. The Ethinyl Estradiol has a half-life of about 24 hours, while desogestrel has a half-life of 14-16 hours.

Route of Elimination

Cyred is eliminated from the body mainly in the form of glucuronide and sulfate conjugates via the kidneys and biliary system into the feces.

Dosage

Cyred is available as a pill taken on a 21-day cycle; each pill capsule contains 0.15 mg of ethinyl estradiol and 0.15mg of desogestrel. It is recommended that new users take the pill for 21 days and then take the next 7 pills with no active medications (placebos) to allow a menstrual cycle to occur.

Administration

Cyred is taken orally usually once daily at the same time every day. It is important to note that a woman's hormone levels may become irregular if she misses more than 2 consecutive doses.

Side Effects

Common side effects of Cyred include headache, nausea, breast pain and tenderness, changes in menstrual spotting or bleeding patterns, abdominal cramps, and mood changes. Less common and more serious side effects include thromboembolism, stroke, heart attack, and an increased risk of liver tumors.

Toxicity

The toxicity of Cyred is relatively low. However, it is important to take the lowest dose possible to reduce the risk of adverse side effects. If the medication is taken as directed, serious toxicity is unlikely to occur.

Precaution

Before taking Ethinyl Estradiol + Desogestresl, it is important to discuss with a healthcare professional if a woman is pregnant, has a history of blood clots, heart attack, or stroke, or has any other medical condition that can be affected by the drug. Additionally, it is important to discuss with a healthcare professional any circumtances that may increase one's likelihood of developing side effects such as smoking, drinking alcohol, or using illicit substances.

Interaction

Drug interactions can occur with Cyred, and it is important to discuss with a healthcare professional any other medications taken before starting this OCP. Specifically, drugs that may decrease the efficacy of this medication include rifampin, phenytoin,carbamazepine, certain antibiotics, herbal products, and certain antifungal drugs.

Disease Interaction

Women with pre-existing medical conditions may need to be especially cautious when using Cyred. Certain disease states can cause increased risks and side effects such as hypertension, diabetes, coronary artery disease, and obesity.

Drug Interaction

Drug interactions can occur with Cyred, and it is important to discuss with a healthcare professional any other medications taken before starting this OCP. Specifically, drugs that may decrease the efficacy of this medication include rifampin, phenytoin,carbamazepine, certain antibiotics, herbal products, and certain antifungal drugs.

Food Interactions

Foods that may interact with Cyred include grapefruit, chocolates, spinach, and green tea leaves which may decrease the medicinal efficacy of the OCP. It is important to talk to a doctor before consuming any of these foods.

Pregnancy Use

Cyred is generally not recommended for use in pregnant women. However, in the event of a missed pill that leads to pregnancy, a doctor should be consulted to discuss the risks as soon as possible.

Lactation Use

Cyred should be avoided by lactating mothers. It is recommended to use an alternate form of contraception, such as a condom, while breastfeeding.

Acute Overdose

In case of an acute overdose of Cyred, seek medical attention immediately. Symptoms of an acute overdose may include changes in heart rate, nausea, vomiting, dizziness, or uncontrolled movements.

Contraindication

Cyred is contraindicated in women with a history of traumatic cerebrovascular accidents, deep vein thrombosis, thromboembolism, or an impairment of liver function. Additionally, women who are found to have Texas or other high risk papillomavirus infections should also avoid taking this OCP.

Use Direction

Cyred should be taken for 21 consecutive days and a 7 day break should follow before starting the next cycle. The pill should be taken at approximately the same time each day. Missing more than two consecutive pills may increase the risk of pregnancy.

Storage Conditions

Cyred should be stored at room temperature and kept out of direct sunlight and away from sources of moisture and heat. It should be kept out of reach of children and pets.

Volume of Distribution

The volume of distribution for Cyred is approximately 4 liters per kg.

Half Life

The half life of Ethinyl Estradiol is about 24 hours and the half life of desogestrel is around 14-16 hours.

Clearance

The clearance rate for Cyred is approximately 33 ml per minute per kg.

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