Cortisol

Cortisol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cortisol is a brand name. Its generic name is Clobetasol Propionate.

Introduction

Cortisol is a synthetic corticosteroid drug, used topically to reduce inflammation to treat certain skin conditions such as eczema, psoriasis, and dermatitis. It is a derivative of prednisolone and is a potent drug, available in cream, ointment, foam, and aerosol solutions for topical use. It is also known as cormex, clobex, clodan, clocort, olux, and temovate.

Uses For

Cortisol is primarily used to treat inflammatory skin diseases such as eczema, psoriasis, and lichen planus. It helps reduce itching, redness, and irritation associated with these conditions. It can also be used to treat alopecia areata, an autoimmune disorder that causes hair loss.

Mechanism Of Action

Cortisol works by inhibiting the production of certain inflammatory substances in the body. These substances can cause itching, redness, and inflammation when produced in excess. Cortisol works to reduce this inflammation and thus reduce the symptoms associated with skin conditions.

How Long Does It Take To Work

Cortisol usually takes effect within 12 hours of application. The effects typically last for up to four weeks, depending on the severity of the condition being treated.

Absorption

Cortisol is rapidly absorbed through the skin. Studies have shown that 5-15% of the drug is absorbed into the bloodstream following topical application.

Route of Elimination

Cortisol is eliminated from the body primarily in the urine and feces.

Dosage

Cortisol is available in a variety of forms, including creams, ointments, foam, and aerosols for topical use. The dosage of Cortisol depends on the patient’s age, weight, and the severity of the condition being treated. A doctor can provide a more precise dosage schedule, depending on the patient’s individual needs.

Administration

Cortisol should be applied to the affected area of the skin only. It should not be applied to the face, scalp, groin, axillae, or other sensitive areas of the body. Wash hands thoroughly after application.

Side Effect

Common side effects of Cortisol include burning, itching, dryness, irritation, stinging, redness, and peeling skin. Rare side effects include hives, swelling of the face, lips, tongue, or throat, difficulty breathing, vision problems, dizziness, and rash.

Toxicity

Cortisol can be toxic if too much is applied or if it is applied over a large area of skin or an area of skin with ulceration or broken skin. Ingestion of Cortisol can lead to severe symptoms such as lethargy, nausea, vomiting, and abdominal pain.

Precaution

Cortisol should only be used as directed by a doctor or pharmacist and must not be ingested. It should not be used for more than two weeks on an area of skin that is larger than 50 cm2. If the symptoms persist, the patient should seek medical help. Avoid contact with eyes and wash hands thoroughly after application.

Interaction

Cortisol may interact with certain drugs, such as other corticosteroid drugs, alcohol, or certain antibiotics. It is important for patients to inform their doctor or pharmacist of all medications they are taking in order to reduce the risk of interactions.

Disease Interaction

Cortisol should not be used by people with certain diseases, such as tuberculosis, diabetes, osteoporosis, congestive heart failure, ulcerative colitis, glaucoma, and hypersensitivity to corticosteroids.

Drug Interaction

Cortisol may interact with certain drugs, such as other corticosteroid drugs, alcohol, or certain antibiotics. It is important to inform the doctor or pharmacist of all medications that are being taken in order to reduce the risk of interactions.

Food Interactions

Cortisol is not known to interact with food. However, it should be used with caution in individuals with known allergic reactions to certain foods or ingredients.

Pregnancy Use

Cortisol should not be used during pregnancy. It should be avoided in nursing mothers and in women planning to become pregnant.

Lactation Use

Cortisol should not be used during lactation.

Acute Overdose

Overdose of Cortisol can lead to systemic side effects, such as high blood pressure, rapid heart rate, confusion, mood changes, and kidney damage. If overdose is suspected, the patient should seek medical help immediately.

Contraindication

Cortisol should not be used by people with certain diseases, such as tuberculosis, diabetes, osteoporosis, congestive heart failure, ulcerative colitis, glaucoma, and hypersensitivity to corticosteroids.

Use Direction

Cortisol is for external use only. It should be applied sparingly to the affected area one to three times daily. Wash hands thoroughly after application.

Storage Condition

Cortisol should be stored at room temperature, away from heat, light, and moisture. It should be kept away from children and pets.

Volume of Distribution

The volume of distribution of Cortisol is not known.

Half Life

The half-life of Cortisol is approximately two days.

Clearance

The clearance of Cortisol is not known.

Here you find in details version of Cortisol

Some Frequently Asked Questions About Cortisol

What is Cortisol?

Cortisol is a highly potent topical corticosteroid that is used to treat various skin conditions such as psoriasis, eczema, atopic dermatitis, and other areas of inflammation or irritation.

How does Cortisol work?

Cortisol works by reducing inflammation in the skin and decreasing the activity of the immune system. This helps to reduce symptoms such as itching, swelling, redness, and irritation.

What are the side effects of Cortisol?

Common side effects of Cortisol include skin irritation, burning, stinging, itching, redness, thinning of the skin, and acne. More serious side effects may include increased hair growth, streaking or lightening of the skin, stretch marks, and other changes to your skin.

Is Cortisol safe to use in children?

Yes, Cortisol can be safely used in children, but only under the supervision of a doctor. Children should not apply more than recommended, and should not use it for longer than directed by a doctor.

Is Cortisol available over the counter?

No, Cortisol is a prescription medication that is not available over-the-counter.

What happens if I use Cortisol too often?

Using Cortisol too often can cause additional skin irritation, changes in the skin, and systemic side effects. It is important to follow your doctor's directions when using Cortisol.

How often can I use Cortisol?

The frequency of use will depend on the condition being treated. It is important to follow your doctor's instructions with regards to use.

How often should I apply Cortisol?

Cortisol should be applied as directed by your doctor. Generally, it is recommended to apply the medication up to 2 times daily.

Does Cortisol have to be prescribed?

Yes, Cortisol is a prescription medication and should only be used under the supervision of a doctor.

How long can I use Cortisol?

The duration of use will depend on the condition being treated. It is important to follow your doctor's instructions and not use the medication for longer than directed.

What should I avoid while using Cortisol?

It is important to avoid prolonged use of the medication, contact with eyes and mouth, and the use of irritating skin products or cosmetics while using Cortisol.

Does Cortisol expire?

Yes, Clobetasol Propionte does expire. It is important to check the expiration date and discard any expired medication.

Is Cortisol safe during pregnancy?

There are no adequate studies on Cortisol and pregnancy. It is generally recommended to avoid use during pregnancy, unless directed by a doctor.

Can Cortisol be used for insect bites?

No, Cortisol should not be used for insect bites. This medication is reserved for skin conditions that require a topical corticosteroid.

Should I wash my hands after applying Cortisol?

Yes, it is important to wash your hands after applying Cortisol. This helps to avoid inadvertent transfer of the medication to other areas of the body.

Can Cortisol be used on the face?

Yes, Cortisol can be used on the face, but it should only be done so under the supervision of a doctor. It is important to follow dosing instructions and use the minimum amount possible on the face.

Is Cortisol safe for long-term use?

No, long-term use of Cortisol is not recommended, as this medication can cause changes to your skin, as well as other side effects.

Can Cortisol be used along with other medications?

Yes, Cortisol can be used in conjunction with other medications, but it is important to check with your doctor before using any other products on the same area.

Can Cortisol be used on the scalp?

Yes, Cortisol can be used on the scalp, but it should only be used under the supervision of a doctor. It is important to follow dosing instructions and use the minimum amount possible on the scalp.

Can I use a moisturizer with Cortisol?

Yes, you can use a moisturizer with Cortisol, but it is important to check with your doctor before using any additional products on the same area.

What should I do if I get Cortisol in my eyes?

It is important to remove the medication and seek medical attention if Cortisol gets into your eyes. Wash the area with lukewarm water and contact your doctor immediately.

Can Cortisol be used for sunburn?

No, Cortisol should not be used for sunburn. Sunburns should be treated with products specifically designed for that purpose.

Can I use a bandage with Cortisol?

Yes, a bandage can be used with Cortisol, but it is important to check with your doctor before using any additional products on the same area.

Is Cortisol the same as hydrocortisone?

No, Cortisol is not the same as hydrocortisone. Cortisol is a much more potent topical corticosteroid than hydrocortisone.

Is Cortisol good for acne?

Cortisol is not recommended for acne, as it may make the condition worse. There are other medications that may be used to treat acne.

Will Cortisol clear up my skin?

Cortisol can help clear up skin, but the results may vary depending on the condition being treated. Always follow your doctor's instructions when using Cortisol.

How long does it take for Cortisol to work?

Cortisol typically starts working within a few days, but it may take 2-3 weeks to notice the full effects of the medication.

Are there other corticosteroids available?

Yes, there are other topical corticosteroids available such as hydrocortisone, mometasone, and fluticasone. It is important to check with your doctor before using any of these medications.

Does Cortisol need to be refrigerated?

No, Cortisol does not need to be refrigerated. It should be stored at room temperature away from light and moisture.

Can I wear makeup while using Cortisol?

Yes, you can wear makeup while using Cortisol, but it is important to check with your doctor before using any of the products on the same area.

Does Cortisol work for ringworm?

Yes, Cortisol can be used to treat ringworm. It is recommended to apply the medication twice daily for up to two weeks.

Are there any alternatives to Cortisol?

Yes, there are other topical corticosteroids such as hydrocortisone, mometasone, and fluticasone that can be used to treat skin conditions. It is important to check with your doctor before using any of these medications.

What should I do if I am allergic to Cortisol?

If you experience any signs of an allergic reaction, such as itching, swelling, rash, or difficulty breathing, stop using the medication and seek medical attention immediately.

Can I apply Cortisol on broken skin?

No, Cortisol should not be applied to broken skin. Wait for the area to heal and talk to your doctor before applying the medication.

Can Cortisol be used for eczema?

Yes, Cortisol can be used to treat various symptoms of eczema, such as itching, swelling, redness, and irritation.

Can I use Cortisol on my hands?

Yes, Cortisol can be used on your hands, but it should only be done so under the supervision of a doctor. It is important to follow dosing instructions and use the minimum amount possible on the hands.

Can Cortisol be used on scalp during pregnancy?

No, Cortisol should not be used during pregnancy, unless directed by your doctor. Talk to your doctor about any alternatives that might be safer during pregnancy.

Can I use sunscreens with Cortisol?

Yes, you can use sunscreens with Cortisol, but it is important to check with your doctor before using any additional products on the same area.

Is Cortisol effective against rash?

Yes, Cortisol can be used to treat various skin conditions, including rash. It is important to follow your doctor's instructions when using Cortisol.

Does Cortisol have an odor?

No, Cortisol does not have an odor. It is important to follow your doctor's instructions when using this medication.

What happens when I stop using Cortisol?

When you stop using Cortisol, your symptoms may recur. It is important to stop using the medication at the right time and follow your doctor's instructions.

Is Cortisol safe for long-term use?

No, long-term use of Cortisol is not recommended, as this medication can cause changes to your skin, as well as other side effects.

Does Cortisol expire?

Yes, Clobetasol Propionte does expire. It is important to check the expiration date and discard any expired medication.

What should I do if I get Cortisol in my eyes?

It is important to remove the medication and seek medical attention if Cortisol gets into your eyes. Wash the area