Coliret

Coliret Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Coliret is a brand name. Its generic name is Dicyclomine.

Introduction

Coliret is an antispasmodic and anticholinergic used to treat abdominal cramping, spasms, and pain associated with irritable bowel syndrome (IBS) and other gastrointestinal (GI) disorders. It works by blocking the action of the neurotransmitter, acetylcholine, which helps reduce muscle spasms and cramping in the gut.

Uses For

Coliret is used to treat abdominal discomfort, cramping, and pain associated with irritable bowel syndrome. It may also be used to treat spasms caused by other GI disorders.

Mechanism of Action

Coliret works by blocking the action of the neurotransmitter acetylcholine, which helps reduce muscle spasms and cramping in the gut. This action helps relieve the abdominal discomfort, cramping, and pain associated with irritable bowel syndrome and other GI disorders.

How Long Does it Take to Work?

Coliret typically begins to work within one to two hours after it is taken.

Absorption

Coliret is rapidly and almost completely absorbed after oral administration.

Route of Elimination

Coliret is almost completely metabolized in the liver and is excreted in the urine as metabolites and in the feces.

Dosage

Coliret tablets are usually taken four times daily. The recommended dose is 10 mg to 20 mg, four times per day, 1 to 2 hours before meals and/or at bedtime.

Administration

Coliret can be taken with or without food. It is recommended to take dicyclomine with food or milk to prevent stomach irritation.

Side Effects

Common side effects include dry mouth, constipation, blurred vision, drowsiness, dizziness, difficulty urinating, and headache.

Toxicity

Overdoses of dicyclomine can result in extreme drowsiness, dry mouth, dilated pupils, flushing, fever, seizures, and in severe cases, coma.

Precautions

Coliret can be habit-forming and may cause severe drowsiness. Patients should avoid drinking alcohol, driving, or operating machinery while taking dicyclomine.

Interactions

Coliret can interact with certain medications, including anticholinergics, some antidepressants, antipsychotics, antihistamines, and antifungals.

Disease Interactions

Coliret may not be suitable for patients with certain heart conditions, prostate problems, glaucoma, and some types of lung disease.

Drug Interactions

Coliret may interact with certain drugs, including some antacids, antibiotics, antidepressants, antifungals, antihistamines, and antipsychotics.

Food Interactions

Taking dicyclomine with food may decrease stomach irritation. However, it is important to avoid drinking grapefruit juice or eating grapefruit while taking dicyclomine as they may increase drug levels, causing side effects.

Pregnancy Use

Coliret should not be taken during pregnancy as it may cause harm to the fetus.

Lactation Use

Coliret should not be taken during breastfeeding as the drug may pass into breastmilk, causing unwanted side effects in the baby.

Acute Overdose

In the event of an acute overdose, seek immediate medical attention. Symptoms of an overdose may include extreme drowsiness, dry mouth, dilated pupils, flushing, fever, seizures, and in severe cases, coma.

Contraindication

Coliret should not be taken by patients with ulcerative colitis, hiatal hernia, myasthenia gravis, obstructive diseases of the gastrointestinal tract, obstructive diseases of the bladder or the bile ducts, or in patients with hypersensitivity to the drug.

Use Direction

Follow the instructions for taking dicyclomine as prescribed by your doctor. Do not take more or less than prescribed. Do not abruptly stop taking dicyclomine as it may worsen symptoms.

Storage Condition

Coliret should be stored at room temperature (15-30°C). Keep out of reach of children.

Volume of Distribution

The volume of distribution of dicyclomine is not known.

Half Life

The elimination half-life of dicyclomine is approximately 4 to 6 hours.

Clearance

The clearance of dicyclomine is not known.

Here you find in details version of Coliret

Some Frequently Asked Questions About Coliret

What is Coliret?

Coliret is a medication used to treat muscle spasms in the gut commonly caused by irritable bowel syndrome (IBS). It belongs to a group of drugs called anticholinergics/antispasmodics.

How does Coliret work?

Coliret works by blocking certain chemicals in the nervous system that lead to muscle contractions in the gut. This helps relieve spasms and associated pain, discomfort, and bloating.

What are the side effects of Coliret?

The most common side effects of Coliret are dry mouth, dizziness, blurred vision, headache, and restlessness. Other less common side effects include difficulty urinating, fast heartbeat, nausea, constipation, stomach pain, and insomnia. Contact your doctor if you experience any of these side effects.

How long does it take for Coliret to work?

It usually takes about 1 hour for Coliret to take effect. The maximum effects of the medication should be felt within 3 to 4 hours after taking the dose.

How should I take Coliret?

Coliret should be taken orally with a full glass of water. Do not break, chew, or crush the tablet before taking it. Take the missed dose as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.

How often can I take Coliret?

Coliret should be taken every 6-8 hours as needed for abdominal discomfort. The daily dose should not exceed 4 tablets per day, and the total daily dose should not exceed 30mg.

Can I take Coliret with food?

Yes, Coliret can be taken with or without food. However, it is recommended to take it with food as it may decrease the chances of an upset stomach.

Are there any precautions I should be aware of before taking Coliret?

Coliret should not be taken with alcohol, as it can increase the risk of side effects such as drowsiness, dizziness, and fast heartbeat. Coliret should also not be taken with other medications that can cause drowsiness, such as antihistamines, muscle relaxants, and sleep aids. Tell your doctor about all the medications you are currently taking before starting Coliret.

Is Coliret safe during pregnancy?

Coliret should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Talk to your doctor about the risks and benefits of taking Coliret while pregnant.

Is Coliret safe for children?

Coliret should not be used in children younger than 6 years old. Talk to your doctor about the risks and benefits of giving Coliret to a child.

Can I take Coliret with other medications?

Coliret can interact with certain drugs, so it is important to tell your doctor about all the medications you are currently taking before starting Coliret. This includes both prescription and over-the-counter medications, as well as herbal supplements and vitamins.

What if I forget to take a dose of Coliret?

If you forget to take a dose of Coliret, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

What should I do if I have an allergic reaction to Coliret?

If you have an allergic reaction to Coliret such as hives, difficulty breathing, swelling of the face, lips, tongue, or throat, seek medical help immediately. Stop taking Coliret and contact your doctor right away.

Is there a generic version of Coliret available?

Yes, there is a generic version of Coliret available. The generic name is dicycloverine, and it is available in 10mg tablets.

How should I store Coliret?

Coliret should be stored at room temperature away from light and moisture. Keep the tablets in a tightly sealed container and out of reach of children.

What are the symptoms of Coliret overdose?

Symptoms of Coliret overdose may include confusion, seizures, severe drowsiness, fast heartbeat, slow breathing, dry mouth, fever, agitation, and blurred vision. If you believe someone has taken an overdose of Coliret, call your local poison control center or seek medical help right away.

Does Coliret cause weight gain?

No, Coliret does not typically cause weight gain. However, it may cause an increase in appetite, leading to weight gain if excess calories are consumed.

Can I drink alcohol while taking Coliret?

No, you should not drink alcohol while taking Coliret, as it can increase the risk of side effects such as nausea, vomiting, dizziness, and lightheadedness. Talk to your doctor about the risks and benefits of drinking alcohol while taking Coliret.

Does Coliret lower blood pressure?

No, Coliret does not typically lower blood pressure. However, it may cause a decrease in heart rate, which could lead to a drop in blood pressure.

Can I take Coliret if I have glaucoma?

Yes, you can take Coliret if you have glaucoma, but it is important to talk to your doctor about any risks. Coliret may cause an increase in the pressure in your eyes, which can make glaucoma worse.

Is Coliret a controlled substance?

No, Coliret is not a controlled substance. It is available by prescription or over-the-counter in the United States.

Can Coliret cause constipation?

Yes, Coliret can cause constipation as a side effect. If this occurs, talk to your doctor about using a laxative to avoid constipation.

Does Coliret cause dry mouth?

Yes, Coliret can cause dry mouth as a side effect. To prevent or reduce the symptoms, try drinking plenty of fluids and sucking on ice chips.

Can Coliret be crushed or split?

No, Coliret should not be cut, crushed, or split. Doing so can increase the risk of side effects and reduce the effectiveness of the medication.

Does Coliret work for headaches?

No, Coliret is not typically used to treat headaches. It is only used to treat muscle spasms in the gut. Talk to your doctor about the best treatment for your headache.

Does Coliret help with nausea?

No, Coliret is not typically used to treat nausea. It is only used to treat muscle spasms in the gut. Talk to your doctor about the best treatment for your nausea.

Can I take Coliret for cramps?

Yes, Coliret can be used to treat muscle spasms in the gut that result in cramps. Talk to your doctor about the best treatment for your cramps.

What should I avoid while taking Coliret?

You should avoid any activity that requires alertness or clear vision, such as driving or operating heavy machinery. You should also avoid drinking alcohol, as it can increase the risk of side effects. Talk to your doctor about any other activities you should avoid while taking Coliret.

Can I take other medications with Coliret?

Yes, you can take other medications with Coliret, but it is important to tell your doctor about all the medications you are currently taking before starting Coliret. This includes both prescription and over-the-counter medications, as well as herbal supplements and vitamins.

Can Coliret cause drowsiness?

Yes, Coliret can cause drowsiness as a side effect. If this occurs, do not drive or operate heavy machinery until the drowsiness has passed.

Can Coliret cause blurred vision?

Yes, Coliret can cause blurred vision as a side effect. If this occurs, do not drive or operate heavy machinery until the blurred vision has passed.

Is Coliret habit forming?

No, Coliret is not considered to be habit-forming. However, it is important to take Coliret as prescribed and follow your doctor's instructions for discontinuing the medication when it is no longer needed.

Can I take Coliret if I am allergic to sulfa drugs?

Yes, you can take Coliret if you are allergic to sulfa drugs. Coliret does not contain sulfa and is unlikely to cause an allergic reaction.

Is Coliret safe for long-term use?

Yes, Coliret is safe for long-term use, but it is important to talk to your doctor about any risks. Taking Coliret on a long-term basis can increase the risk of side effects such as dizziness, drowsiness, dry mouth, and blurred vision.

Does Coliret cause acne?

No, Coliret does not typically cause acne. However, some people have reported skin rashes or itching while taking the medication, so talk to your doctor if you experience this.

Does Coliret help with diarrhea?

Yes, Coliret can help with diarrhea caused by irritable bowel syndrome. It works by reducing muscle spasms in the gut, which can help relieve the discomfort associated with diarrhea.

Does Coliret help with gas and bloating?

Yes, Coliret can help with gas and bloating by reducing muscle spasms in the gut. This can help to reduce the symptoms of gas and bloating associated with IBS.

Can Coliret be taken with ibuprofen?

Yes, Coliret can be taken with ibuprofen. However, it is important to tell your doctor about all the medications you are currently taking before starting Coliret. This includes both prescription and over-the-counter medications, as well as herbal supplements and vitamins.

Does Coliret help with anxiety?

No, Coliret is not typically used to treat anxiety. Talk to your doctor about the best treatment for your anxiety.

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