Clofenac SR
Clofenac SR Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Clofenac SR is a brand name. Its generic name is Diclofenac.
Introduction
Clofenac SR is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the production of certain natural substances that cause inflammation. Clofenac SR is used to treat pain and inflammation associated with various conditions, including arthritis, muscle sprains and strains, gout, painful menstrual periods, and migraine.
Uses
Clofenac SR is used to treat pain and inflammation associated with various conditions, including arthritis, muscle sprains and strains, gout, painful menstrual periods, and migraine.
Mechanism of Action
Clofenac SR works by blocking the production of certain natural substances that cause inflammation.
Absorption
Clofenac SR is absorbed rapidly and extensively with oral administration.
Route of Elimination
Clofenac SR is mainly eliminated by metabolism in the liver and to a small extent by excretion through the kidney.
Dosage
The recommended dose of diclofenac is 50-100mg, up to three times a day, depending on the condition and individual response. It is generally taken with food or milk to reduce stomach irritation.
Administration
Clofenac SR is available in various forms, including tablets, capsules, and topical gels, or liquid. It is generally taken by mouth with or without food.
Side Effects
Common side effects of diclofenac include nausea, vomiting, stomach upset, headache, dizziness, and drowsiness. Other more serious side-effects include an increased risk of stroke, heart attack, bleeding, and ulcers.
Toxicity
The onset of toxicity is usually at the 75mg dose. Symptoms may include drowsiness, confusion, dizziness, and nausea.
Precaution
Patients should not take diclofenac if they have a history of ulcers, or if they are taking other medications that may increase the risk of bleeding, such as warfarin, aspirin, or any other NSAIDs. In addition, it should be used with caution in patients with high blood pressure, kidney or liver disease, or heart failure.
Interaction
Clofenac SR should not be used with certain medications, including corticosteroids, diuretics, and warfarin. In addition, patients should avoid alcohol, as it can increase the risk of stomach irritation.
Disease Interaction
Clofenac SR should not be used in patients with certain diseases. These include stomach, kidney, or liver diseases, as well as bleeding disorders or heart failure.
Drug Interaction
Clofenac SR may interact with other medications, including antacids, lithium, and warfarin. Patients should talk to their doctor about any medications they are taking before beginning treatment with diclofenac.
Food Interactions
Clofenac SR should not be taken with food. Patients should make sure to take the medication with a full glass of water, and at least one hour before or two hours after meals.
Pregnancy Use
Clofenac SR should not be used during pregnancy, except if clearly necessary. If used, regular monitoring of the baby's condition is advised.
Lactation Use
Clofenac SR should not be used while breastfeeding, as it may pass into breast milk and affect the baby.
Acute Overdose
An overdose of diclofenac can be serious; symptoms may include nausea, vomiting, stomach pain, and dizziness. If an overdose is suspected, contact a doctor or poison control center immediately.
Contraindication
Clofenac SR should not be used in patients with known hypersensitivity to it, or to other NSAIDs. In addition, it should not be used in patients with bleeding disorders, or in patients with a history of ulcer or stomach bleeding.
Use Direction
Clofenac SR should be taken with food, or milk to reduce stomach irritation. It should not be used with alcohol.
Storage Condition
Clofenac SR should be stored at room temperature, and away from moisture and heat. It should be kept away from children and pets.
Volume of Distribution
The volume of distribution of diclofenac is 0.16 L/kg.
Half Life
The half-life of diclofenac is 1.2-2 hours.
Clearance
The clearance of diclofenac is 0.13-0.17 mL/min/kg.
Here you find in details version of Clofenac SR
Some Frequently Asked Questions About Clofenac SR
What is Clofenac SR?
Clofenac SR is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and help relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis) such as inflammation, swelling, stiffness, and joint pain.
What are the benefits of taking Clofenac SR?
Clofenac SR helps reduce inflammation and pain caused by arthritis and lowers fever. It may also help prevent damage to your joints caused by arthritis.
What are the side effects of taking Clofenac SR?
Common side effects of Clofenac SR include stomach pain, heartburn, nausea, vomiting, constipation, and dizziness. More serious side effects including bleeding, ulcers, and kidney and liver problems can also occur.
What should I tell my doctor before taking Clofenac SR?
Tell your doctor about all other medications you are taking, including over-the-counter medicines, vitamins, and supplements. You should also tell your doctor if you are pregnant, breastfeeding, or have any allergies.
Can I take Clofenac SR with other medications?
Clofenac SR can interact with other medications and should not be taken with some medications, including aspirin, ibuprofen, certain blood thinners, and medicines used to treat HIV or cancer. Always consult with your doctor before taking Clofenac SR with other medications.
What is the recommended dosage for Clofenac SR?
The recommended dose of Clofenac SR is 50 to 100 mg taken orally three or four times daily. The dose may be adjusted depending on the condition and response to treatment. Always take Clofenac SR exactly as prescribed by your doctor.
How long does it take for Clofenac SR to work?
The effects of Clofenac SR may be noticeable within one day or may take several days for full effects to be seen. Generally, people start to feel better within two weeks of starting the medication.
Can I take Clofenac SR if I am pregnant or breastfeeding?
Clofenac SR should be avoided in pregnant or breastfeeding women. Talk to your doctor before taking this medication if you are pregnant or breastfeeding.
Is Clofenac SR safe if I have heart failure?
Clofenac SR may worsen some of the symptoms of heart failure, so exercise caution if you have this condition. Consult with your doctor before taking this medication.
Is Clofenac SR a narcotic?
No. Clofenac SR is not a narcotic. It is a nonsteroidal anti-inflammatory drug (NSAID).
Can I take Clofenac SR with food?
Yes, you can take Clofenac SR with or without food. However, taking Clofenac SR with food may decrease the risk of stomach upset.
What if I miss a dose of Clofenac SR?
If you miss a dose of Clofenac SR, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Can Clofenac SR be taken long-term?
Clofenac SR can be taken long-term but should only be used as prescribed by your doctor. Talk to your doctor about any side effects that may occur if taking this medication for an extended period of time.
Can I drink alcohol while taking Clofenac SR?
You should avoid consuming alcohol while taking Clofenac SR. Alcohol can increase the risk of stomach irritation, bleeding, and other side effects.
What should I do if I experience side effects with Clofenac SR?
If you experience side effects with Clofenac SR, consult with your doctor. Your doctor may adjust your dose or suggest an alternate treatment. Do not adjust your dose or stop taking without consulting your doctor.
What is the generic name for Clofenac SR?
The generic name for Clofenac SR is diclofenac sodium.
What is the difference between diclofenac and ibuprofen?
Clofenac SR and ibuprofen are both nonsteroidal anti-inflammatory medications used to treat pain, inflammation, and fever. Ibuprofen is generally better tolerated than Clofenac SR; Clofenac SR can irritate the stomach and cause more side effects.
When should I take Clofenac SR?
Clofenac SR should be taken as prescribed by your doctor. Generally, the recommended dose is one pill taken three or four times daily after meals.
Does Clofenac SR have any interactions with other medications?
Yes, Clofenac SR can interact with some medications. It should not be taken with aspirin, ibuprofen, certain blood thinners, or medicines used to treat HIV or some types of cancer. Talk to your doctor about any other medications you are currently taking to avoid potential interactions.
Is Clofenac SR addictive?
No, Clofenac SR is not an addictive medication.
Is Clofenac SR the same as Naproxen?
No, Clofenac SR and Naproxen are two different medications. Naproxen is another nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammation, pain, and fever.
How long should I stay on Clofenac SR?
The duration of Clofenac SR treatment will vary depending on your condition and response to treatment. Most people start to feel better within two weeks of starting the medication. Talk to your doctor about how long you will need to stay on Clofenac SR.
Can I take Clofenac SR if I have liver disease?
You should avoid taking Clofenac SR if you have liver disease. In some cases, using Clofenac SR can increase your risk of liver problems. Talk to your doctor before taking this medication.
Can Clofenac SR cause weight gain?
No, Clofenac SR does not typically cause weight gain. If you gain weight while taking Clofenac SR, consult with your doctor.
Can I use Clofenac SR for headaches?
No, Clofenac SR is not typically used for headaches. Talk to your doctor about other medications that are more effective for treating headaches.
Will Clofenac SR help me sleep better?
No, Clofenac SR is not typically used for sleep. If you are having difficulty sleeping, talk to your doctor about medications that are more effective for improving sleep.
Can I take Clofenac SR if I am breastfeeding?
No, Clofenac SR should be avoided in breastfeeding women. Talk to your doctor about other options for managing pain while breast-feeding.
Can Clofenac SR cause constipation?
Yes, Clofenac SR can cause constipation. If you experience constipation while taking Clofenac SR, talk to your doctor about treatment options.
Can I take Clofenac SR while pregnant?
No, Clofenac SR should be avoided in pregnant women. Talk to your doctor about other options for managing pain during pregnancy