Clindax-B
Clindax-B Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Clindax-B is a brand name. Its generic name is Clindamycin + Benzoyl peroxide.
Introduction of Clindamycin + Benzoyl Peroxide
Clindamycin + Benzoyl Peroxide is a combination topical medicine used to reduce the number of acne lesions/pimples. It contains the antibiotic clindamycin as well as the antimicrobial benzoyl peroxide and is used to treat moderate to severe acne.Uses of Clindamycin + Benzoyl Peroxide
Clindamycin + Benzoyl Peroxide is used to treat acne. It is most effective when used with other acne treatment products, including topical tretinoin, adapalene, or azelaic acid.Mechanism of Action
Clindamycin inhibits bacterial growth by interfering with the bacterial cell wall synthesis and protein production. Benzoyl peroxide works by helping the skin eliminate bacteria and reducing inflammation. The combination of the two medications helps to effectively reduce the number of acne lesions.How Long Does It Take To Work?
It typically takes 4-6 weeks of consistent, twice-daily use of this medication to see results.Absorption
Clindamycin and Benzoyl Peroxide are both topically absorbed through the skin.Route of Elimination
Clindamycin and Benzoyl Peroxide are both eliminated through the urine and feces.Dosage
The Clindamycin/Benzoyl Peroxide combination is available in several strengths - 1.2 % / 2.5 %, 1 % / 5 %, or 0.75 % / 5 %. Typically, it is applied twice daily for 8 weeks.Administration
Clindamycin/Benzoyl Peroxide should be applied to affected areas of the skin twice daily. It is important to read the patient information leaflet that accompanies the medication and follow the instructions for use carefully. It is important not to apply the medication to excessively dry or irritated skin and to avoid contact with the eyes, mouth, and other sensitive areas.Side Effects
Common side effects of Clindamycin/Benzoyl Peroxide may include dry skin, peeling or burning skin, redness or itching. Others may include rash, stinging, blurred vision, and nausea.Toxicity
Clindamycin/Benzoyl Peroxide is generally safe in adults. There is no known toxic dose for these medications, but they may not be suitable in pregnant or breastfeeding women, as well as in children under 12 years old.Precautions
The use of Clindamycin/Benzoyl Peroxide should not be used in some patients, including those who are allergic to either of the active ingredients, those with kidney/liver problems, and those who have an imbalanced electrolyte levels. It should not be used on sunburned, windburned, dry, chapped, irritated, or broken skin.Interactions
Clindamycin/Benzoyl Peroxide may interact with other medications such as hormonal contraceptives, oral acne medications, or other topical medications. It may also interact with some herbal products or dietary supplements.Disease Interactions
Clindamycin/Benzoyl Peroxide may interact with certain diseases such as asthma, eczema, rosacea, and dermatitis. It is important to tell your healthcare provider if you have any pre-existing medical condition.Drug Interactions
Clindamycin/Benzoyl Peroxide may interact with certain drugs such as vitamins, HIV medications, antifungals, antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).Food Interactions
When taking Clindamycin/Benzoyl Peroxide, it is important to avoid eating or drinking dairy products, as these may increase the absorption of the medication.Pregnancy Use
Clindamycin/Benzoyl Peroxide should not be used during pregnancy. Women who are breastfeeding should also not use this medication.Lactation Use
Clindamycin/Benzoyl Peroxide should not be used during lactation.Acute Overdose
There is no evidence of an acute overdose with Clindamycin/Benzoyl Peroxide. However, if an overdose is suspected, seek medical attention immediately.Contraindication
Clindamycin/Benzoyl Peroxide should not be used in patients who are allergic to clindamycin or benzoyl peroxide.Use Direction
Clindamycin/Benzoyl Peroxide should be applied to affected areas of skin twice daily. Follow the directions provided by your physician or pharmacist.Storage Condition
Clindamycin/Benzoyl Peroxide should be stored at room temperature and away from heat and light. It is important to keep the medication out of reach of children.Volume of Distribution
Clindamycin and Benzoyl Peroxide have a low volume of distribution.Half Life
The half life of Clindamycin and Benzoyl Peroxide is about 6 hours.Clearance
The clearance rate of Clindamycin and Benzoyl Peroxide is about 10 mL/minute/kg.Here you find in details version of Clindax-B