Cinaron

Cinaron Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cinaron is a brand name. Its generic name is Cinnarizine.

Introduction

Cinaron is an anti-vertigo, anti-dizziness and anti-emetic drug which belongs to the group of piperazine derivatives. It is also known as Stugeron or Stugeron Forte in some countries and works by affecting some of the chemicals in your brain.

Uses for

Cinaron is used for the prevention and treatment of symptoms such as vertigo, dizziness, and nausea caused by a variety of conditions including labyrinthitis, Meniere's disease, drug-induced motion sickness, and even by anxiety or stress.

Mechanism of Action

Cinaron works by blocking the action of certain neurotransmitters in the brain, thereby helping reduce the symptoms of vertigo and nausea. It also works to reduce anxiety, which can help reduce the likelihood of the symptoms reoccurring.

How long does it take to work?

Cinaron typically starts to work within an hour, although it can occasionally take up to three hours. Its effects may last up to eight hours, but it is possible for the effects to last up to 24 hours.

Absorption

Cinaron is rapidly absorbed after oral administration, with peak plasma concentrations achieved within 4 hours. It is well absorbed from the gastrointestinal tract and reaches peak plasma concentrations after 4 hours.

Route of Elimination

Cinaron is metabolized in the liver and is excreted mainly via the kidneys. It has a long half-life, with most of the metabolized product being eliminated within seven days.

Dosage

The dosage of cinnarizine depends on the severity and underlying cause of the vertigo or nausea. Generally, it is recommended to take 15 mg to 25 mg three times daily, or as prescribed by a doctor.

Administration

Cinaron should be taken with plenty of fluids. The tablets can be divided into equal smaller doses if needed. It is best to take cinnarizine with or after food to reduce the risk of gastric irritations.

Side Effects

The most common side effects of cinnarizine include: drowsiness, headaches, dry mouth, skin rash, loss of appetite, nausea, vomiting, dizziness, blurred vision, difficulty concentrating, confusion, nervousness, depression, and menstrual irregularities.

Toxicity

Cinaron is considered to be a relatively safe medicine, but high doses can lead to toxicity. Symptoms of an overdose of cinnarizine may include nausea, vomiting, drowsiness, confusion, increased heart rate, decreased blood pressure, and seizures.

Precautions

Before taking cinnarizine, it is important to notify your doctor if you have any other medical conditions, such as kidney or liver disease, heart disease, prostate problems, glaucoma, depression, or any allergies. It is also important to tell your doctor about all medications you are taking, including over-the-counter and herbal medications.

Interactions

Cinaron may interact with other medications, including those that affect the central nervous system, and can lead to serious side effects such as confusion, sedation, and dizziness. It is important to notify your doctor if you are taking any other medications, including over-the-counter and herbal medicines.

Disease Interaction

Cinaron can interact with certain diseases and medical conditions, such as liver or kidney disease, glaucoma, prostate problems, and depression, and can cause serious side effects. It is important to notify your doctor if you have any of these conditions or diseases before taking cinnarizine.

Drug Interaction

Cinaron may interact with certain drugs, including those that act on the central nervous system. Such drugs include benzodiazepines, opioids, antidepressants, antipsychotics, and anticonvulsants. It is important to notify your doctor if you are taking any other medications before taking cinnarizine.

Food Interactions

Cinaron may interact with certain foods, including those that contain caffeine or alcohol, which can increase the risk of adverse side effects. It is important to notify your doctor of any dietary changes or specific foods you consume before taking cinnarizine.

Pregnancy Use

Cinaron should not be taken by pregnant women or those planning to become pregnant, as it can harm the fetus. It is important to notify your doctor if you are pregnant before taking cinnarizine.

Lactation Use

Cinaron should not be taken by nursing mothers, as it can be passed through breast milk and can possibly harm a nursing infant. It is important to notify your doctor of any breastfeeding before taking cinnarizine.

Acute Overdose

If an overdose of cinnarizine is suspected, it is important to immediately seek medical help. Symptoms of an overdose may include nausea, vomiting, drowsiness, confusion, increased heart rate, decreased blood pressure, and seizures.

Contraindication

Cinaron should not be taken by people who are allergic to cinnarizine or any of the ingredients in the medication. It is also not suitable for people with certain health conditions, such as liver or kidney disease, glaucoma, prostate problems, or depression.

Use Direction

Cinaron should be taken as directed by a doctor or pharmacist. The suggested dose is 15 to 25 mg three times daily. The tablets can be divided into equal smaller doses if needed and should be taken with plenty of fluids. It is best to take cinnarizine with or after food to reduce the risk of gastric irritations.

Storage Condition

Cinaron should be stored at room temperature, away from direct light and moisture. Keep it away from children and pets. It should be kept in its original packaging.

Volume of Distribution

Cinaron has a volume of distribution between 1.09 and 1.25 L/kg.

Half Life

Cinaron has an elimination half-life of approximately 15-20 hours.

Clearance

The clearance of cinnarizine is approximately 0.17-0.21 ml/min/kg.

Here you find in details version of Cinaron

Some Frequently Asked Questions About Cinaron

. Q1. What is Cinaron? A1. Cinaron is an antihistamine and anticholinergic drug typically used to treat symptoms such as nausea, vomiting, vertigo, motion sickness, and dizziness. It is also used to treat anxiety and depression. Q2. Who is Cinaron suitable for? A2. Cinaron is suitable for people who are experiencing symptoms of nausea, vomiting, vertigo, motion sickness, and dizziness. It is also used to treat anxiety and depression. Q3. What are the side effects of Cinaron? A3. Common side effects of Cinaron include drowsiness, headache, and dry mouth. More serious side effects that require immediate medical attention include fainting, seizures, difficulty breathing, and confusion. Q4. Should I tell my doctor if I take Cinaron? A4. Yes, it is important to tell your doctor if you take Cinaron, as it can interact with some other medications. Also, it is important to tell your doctor about any other medical conditions that you have, so that they can determine if Cinaron is suitable for you. Q5. What is the recommended dosage of Cinaron? A5. The recommended dosage of Cinaron is one tablet taken twice a day. Dosage may vary depending on individual needs and should be taken as prescribed by your doctor. Q6. Is Cinaron safe for pregnant women? A6. Cinaron is not usually recommended for pregnant women, as there is not enough information to determine its safety for them. If you are pregnant or planning to become pregnant, it is important to talk to your doctor before taking Cinaron. Q7. How long does Cinaron take to work? A7. Cinaron may begin to take effect within 30 minutes after taking it orally. However, it may take up to several days of taking it before the full effect is felt. Q8. Is Cinaron addictive? A8. No, Cinaron is not normally considered to be habit-forming or addictive. However, it is important not to take more than the recommended dose, as this could lead to an increased risk of side effects. Q9. Is Cinaron available over-the-counter? A9. No, Cinaron is a prescription medication and is not available over the counter. Q10. How long does Cinaron stay in the body? A10. Cinaron is metabolized by the liver and is thought to stay in the body for up to 24 hours. Q11. Can I take Cinaron with other medications? A11. Yes, Cinaron can be taken with other medications, but it is important to speak to your doctor first to make sure it is safe. Certain medications may interact with Cinaron and increase the risk of side effects. Q12. Can I drink alcohol while taking Cinaron? A12. It is not recommended to drink alcohol while taking Cinaron, as it can increase drowsiness and lead to an increased risk of side effects. Q13. Is Cinaron safe for children? A13. Cinaron is generally not recommended for children aged 12 or younger. Always talk to your doctor before giving Cinaron to a child. Q14. What foods should I avoid when taking Cinaron? A14. You should avoid alcohol and grapefruit or grapefruit juice when taking Cinaron, as these can interact with the medication and increase the risk of side effects. Q15. Can I drive while taking Cinaron? A15. It is not recommended to drive or operate machinery while taking Cinaron, as it can cause drowsiness and impairment of judgement. Q16. Can I take Cinaron before surgery? A16. You should stop taking Cinaron at least two weeks before having any surgery, as it can increase the risk of side effects. Q17. How should Cinaron be stored? A17. Cinaron should be stored at room temperature and should be kept away from moisture and heat. Do not store Cinaron in the bathroom. Q18. What should I do if I miss a dose of Cinaron? A18. If you miss a dose of Cinaron, take the missed dose as soon as you remember. If it is close to the time for the next dose, skip the missed dose and take only the next regular dose. Do not take a double dose. Q19. Can Cinaron be taken on an empty stomach? A19. It is generally recommended to take Cinaron with or after a meal or snack, as it may decrease the risk of side effects such as nausea and vomiting. Q20. What are the possible drug interactions of Cinaron? A20. Possible drug interactions of Cinaron include anticholinergics, opioids, barbiturates, MAO inhibitors, and certain antihistamines. It is important to let your doctor know about any other medications you take, so that they can decide if Cinaron is safe for you. Q21. Is Cinaron safe for seniors? A21. Cinaron is safe for seniors, but it is important to let your doctor know about any other medications you take, and any other medical conditions you may have, so that they can decide if Cinaron is safe for you. Q22. Can Cinaron cause constipation? A22. Yes, one of the known side effects of Cinaron is constipation. If you experience constipation, it is important to talk to your doctor as they may recommend changes to your diet or medication to help alleviate the symptoms. Q23. Is Cinaron safe for breastfeeding mothers? A23. Cinaron is usually not recommended for breastfeeding mothers due to lack of data. Always talk to your doctor before taking Cinaron if you are breastfeeding. Q24. Is Cinaron safe for those with liver problems? A24. Cinaron may not be suitable for those with liver problems, as it may worsen their condition. Always talk to your doctor before taking Cinaron if you have liver problems. Q25. What is the best way to take Cinaron? A25. Cinaron tablets should be swallowed whole with a glass of water. Do not take the tablets with alcohol or grapefruit juice, as these can interact with the medication and increase the risk of side effects. Q26. Is Cinaron safe for those with kidney problems? A26. Cinaron may not be suitable for those with kidney problems. Always talk to your doctor before taking Cinaron if you have kidney problems. Q27. Is Cinaron safe for those with asthma? A27. Cinaron may not be suitable for those with asthma, as it may worsen their condition. Always talk to your doctor before taking Cinaron if you have asthma. Q28. Can Cinaron cause weight gain? A28. Cinaron can cause weight gain in some people. If you experience weight gain while taking Cinaron, it is important to talk to your doctor as they may be able to recommend ways to counter this. Q29. Is Cinaron safe for those with diabetes? A29. Yes, Cinaron is generally considered safe for people with diabetes. However, it is important to talk to your doctor before taking Cinaron if you have diabetes, to make sure it is the right medication for you. Q30. Can Cinaron cause blurry vision? A30. Blurry vision is a known side effect of Cinaron. If you experience blurry vision while taking Cinaron, it is important to tell your doctor as they may recommend an alternative or suggest ways to reduce the side effect.