Chlormezanone, a brand name for a formulation containing essential Chlormezanone, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Chlormezanone, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.


Chlormezanone is a non-opioid anti-inflammatory drug, which is used for relieving pain, inflammation, or stiffness associated with various conditions. It is structurally similar to mefenamic acid, but is more effective in treating certain conditions.

Uses for

Chlormezanone is used for the treatment of pain, inflammation, and stiffness associated with arthritis, muscle and bone injuries, and musculoskeletal disorders such as chronic low back pain. This drug is also used to treat menstrual pain, fever, and problems associated with other medical conditions.

Mechanism of Action

Chlormezanone works by decreasing production of prostaglandins, which are molecules that play an important role in causing pain and inflammation. It binds to and inhibits cyclooxygenase enzymes, which are responsible for the conversion of arachidonic acid to prostaglandins. As a result, inflammation and pain are reduced.

How Long Does It Take to Work?

Chlormezanone typically begins to work within 30 minutes after taking the medication.


Chlormezanone is rapidly and almost completely absorbed in the gut following oral administration. It is metabolized in the liver and then excreted in the urine.

Route of Elimination

Chlormezanone is eliminated from the body mainly through the urine.


The recommended dose of chlormezanone is 500 to 1000 mg per day, taken as two or three divided doses.


Chlormezanone is usually taken orally, with or without food. It is available in capsules, tablets, and oral suspension.

Side Effects

Common side effects associated with chlormezanone include: abdominal pain, nausea, vomiting, diarrhea, constipation, dizziness, headache, and skin rash.


Chlormezanone has a low potential for toxicity. However, long-term use of chlormezanone can increase the risk of liver toxicity.


Patients taking chlormezanone should not take any nonprescription medications without first consulting a doctor. Alcohol and other drugs can interact with chlormezanone and increase the risk of serious side effects.


Chlormezanone can interact with other medications, including some antibiotics, antifungal medications, blood-thinning medications, and anti-seizure medications. It is important to tell your doctor about all medications you are taking.

Disease Interaction

Patients with certain medical conditions, such as liver or Kidney Disease, may be at an increased risk for serious side effects when taking chlormezanone.

Drug Interaction

Chlormezanone can interact with certain drugs, including some antibiotics, antifungal medications, blood-thinning medications, and anti-seizure medications. It is important to tell your doctor about all medications you are taking.

Food Interactions

Chlormezanone may interact with certain foods or beverages, including grapefruit juice and alcohol. Therefore, it is important to talk to your doctor about any food or beverage that may interact with chlormezanone.

Pregnancy Use

Chlormezanone is classified as a Pregnancy Category B drug and is considered safe to use during pregnancy. However, pregnant women should talk to their doctor before taking chlormezanone.

Lactation Use

Chlormezanone is excreted into breast milk and is therefore not safe for use in breastfeeding mothers.

Acute Overdose

An acute overdose of chlormezanone can be dangerous and may be fatal. The most common symptoms include abdominal pain, nausea, vomiting, headache, and dizziness. If you think you or someone else has taken an overdose of chlormezanone, seek emergency medical help right away.


Chlormezanone should not be used in patients with known hypersensitivity or allergy to the drug.

Use Direction

Chlormezanone should be taken as directed by a doctor. The dosage, frequency, and duration of the medication should not be changed without the approval of a doctor.

Storage Condition

Chlormezanone should be stored at room temperature, in an air-tight container, away from light and moisture.

Volume of Distribution

Chlormezanone has a volume of distribution of approximately 1.1 L/kg.


The half-life of chlormezanone is approximately 2.3 hours.


Chlormezanone has a total body clearance of approximately 0.6 L/kg/hr.

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