Cero-HC

Cero-HC Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cero-HC is a brand name. Its generic name is Ciprofloxacin + Hydrocortisone Acetate.

Introduction

Cero-HC is a combination product used for the treatment of otitis externa (ear infection) or swimmer's ear. Ciprofloxacin belongs to a class of drugs called quinolone antibiotics which are used to kill bacteria. Hydrocortisone acetate is used to reduce the inflammation and pain associated with the ear infection. This combination is available in both generic and brand form.

Uses

Cero-HC is used for the treatment of outer ear infections caused by bacteria or fungi. These infections include swimmer's ear (otitis externa) and inflammation of the ear canal (external otitis).

Mechanism of Action

Ciprofloxacin is an antibiotic that kills bacteria. It works by interfering with the bacterial DNA, preventing the bacteria from reproducing. Hydrocortisone acetate is a corticosteroid that reduces inflammation and swelling.

How Long Does It Take to Work?

The effects of Cero-HC will become apparent after a few days of treatment. However, it is important to take the medicine as directed by your healthcare provider.

Absorption

Ciprofloxacin is rapidly and completely absorbed from the gut after oral administration. Hydrocortisone is absorbed from the gut and absorbed from the skin after topical application.

Route of Elimination

Ciprofloxacin is primarily eliminated through urine. Hydrocortisone is primarily eliminated through the kidneys.

Dosage

Cero-HC comes in a suspension, or liquid, form. It is typically taken three times a day. The recommended dose in adults and children over 12 months of age is 5-10 drops or 0.25-0.50 mL of suspension. It is important to speak to your healthcare provider for specific dosing instructions as these may vary depending on the individual.

Administration

Cero-HC is administered as an ear drop or suspension directly into the ear. It is important to consult your healthcare provider for specific administration instructions.

Side Effects

The most common side effects of Cero-HC include a burning sensation in the ear, temporary hearing loss, itching, redness or swelling around the ear, and a strange taste in the mouth. More severe, though less common, side effects may include an allergic reaction, dizziness, blurred vision, and rash.

Toxicity

Cero-HC is generally well tolerated. However, if taken in large doses, it may cause some serious side effects. If you experience any of these side effects, seek medical attention immediately.

Precautions

It is important to speak to your healthcare provider before taking Cero-HC. It is important to tell your doctor if you are pregnant or breastfeeding, have kidney or liver disease, or have had an ear infection before.

Interactions

Cero-HC may interact with other medications. It is important to tell your healthcare provider about all the medications you are taking, including over the counter medications, vitamins, and herbal remedies.

Disease Interactions

Cero-HC may worsen certain health conditions. Tell your healthcare provider if you have diabetes, glaucoma, asthma, or any other health condition.

Drug Interactions

Cero-HC may interact with certain other medications. Check with your healthcare provider if you are taking any other medications.

Food Interactions

Cero-HC does not interact with food.

Pregnancy Use

Cero-HC should only be used during pregnancy if the benefit outweighs the risk. It is important to speak to your healthcare provider about the risks and benefits of using this medication during pregnancy.

Lactation Use

Cero-HC should be used with caution in women who are breastfeeding. It is important to speak to your healthcare provider about the risks and benefits of using this medication while breastfeeding.

Acute Overdose

If an overdose is suspected, seek medical attention right away. Some common symptoms of an overdose include nausea, vomiting, drowsiness, dizziness, and confusion.

Contraindication

Cero-HC should not be used in people who are allergic to ciprofloxacin or any other ingredients of the medication.

Use Direction

Follow the instructions given by your healthcare provider when taking Cero-HC. Do not take the medication more often than prescribed or for longer than instructed.

Storage Condition

Cero-HC should be stored at room temperature between 59-86°F (15-30°C). Keep the medication in a cool, dry place away from direct light and moisture.

Volume of Distribution

Ciprofloxacin is widely distributed in the body, with a volume of distribution of 0.4 L/kg. It is not known how much of the hydrocortisone acetate in the suspension is absorbed.

Half Life

Ciprofloxacin has a half-life of 4-5 hours, while hydrocortisone has a half-life of 18-36 hours.

Clearance

Ciprofloxacin has an oral clearance of 0.25 L/hr/kg and a renal clearance of 0.05- 0.07 L/hr/kg. It is not known how much of the hydrocortisone acetate in the suspension is cleared.

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