Cephradine

Cephradine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cephradine is a brand name. Its generic name is Cefradine.

Introduction

Cephradine is an antibiotic drug commonly used for treatment of infections caused by bacteria. It is a first-generation cephalosporin and belongs to the class of cephalosporins. It is a semi-synthetic antibiotic, which means that it has been made in a laboratory from natural substances.

Uses for

Cephradine is used to treat a variety of infections, including but not limited to respiratory infections, skin infections, chest infections, urinary tract infections, and some sexually transmitted diseases.

Mechanism of Action

Cephradine works by inhibiting the bacteria's ability to make proteins which are an important part of its structure, function, and multiplication. By inhibiting this process, cefradine is able to kill the bacteria and prevent it from multiplying.

How Long Does it Take to Work?

Cephradine usually starts to work within a few hours of taking the medication. However, depending on the type of infection being treated, it can take up to several days before the symptoms start to clear up.

Absorption

Cephradine is mostly absorbed from the gastrointestinal tract, with the exception of the dose taken rectally. The majority of an oral dose is absorbed within 3 hours, with peak plasma concentrations occurring after 4-6 hours.

Route of Elimination

Cephradine is eliminated largely from the urine as the unchanged form. Some is also excreted in the feces via biliary excretion. The half-life is in the range of 1-2 hours.

Dosage

Cephradine is available in the form of tablets, capsules, and soluble tablets. The usual adult dosage ranges from 500mg to 1000mg twice daily, depending on the severity of the infection being treated.

Administration

Cephradine should be taken orally with a glass of water, preferably one hour before or two hours after meals, or as directed by the healthcare provider. It is important not to take cefradine with food as this interferes with absorption. For rectal administration, the dose should be dissolved in a small amount of water.

Side Effect

Common side effects of cefradine include nausea, vomiting, abdominal pain, diarrhea, skin rash, oral thrush, and vaginal itching. More serious side effects include anemia, jaundice, fever, and seizures.

Toxicity

Cephradine is generally safe and well tolerated at the recommended dosage. Overdose can lead to symptoms such as renal failure, seizures, and blood disorders.

Precautions

Cephradine should be used with caution in patients with liver or kidney disease, and in those taking other medications such as anticoagulants, oral contraceptives, and diuretics. It should also be used with caution in pregnant and breastfeeding women.

Interactions

Cephradine may interact with other drugs and should not be taken in combination with other antibiotics, sedatives, or anticoagulants. It also interacts with some herbs and supplements, including ginkgo biloba, garlic, and St. John's Wort.

Disease Interaction

Cephradine has been known to interact with certain diseases, including kidney and liver disease, which may affect its effectiveness or cause side effects. It may also interact with other diseases, such as diabetes, which can alter its metabolism and increase its potential for side effects.

Drug Interactions

Cephradine may interact with other drugs including anticoagulants, oral contraceptives, and diuretics. Taking cefradine simultaneously with these drugs may increase the risk of side effects. Additionally, cefradine may increase the risk of bleeding when taken with other drugs that increase blood clotting time.

Food Interactions

Cephradine should be taken one hour before or two hours after meals. Taking it simultaneously with food may reduce its effectiveness. It should also not be taken with dairy products, including milk, cheese, and yogurt, as this may reduce its absorption rate.

Pregnancy Use

Cephradine should be used with caution in pregnant women. There is limited evidence regarding the safety of cefradine during pregnancy. If used, the lowest effective dosage should be used for the shortest duration possible.

Lactation Use

Cephradine should be avoided during lactation as it is excreted in breast milk. If it must be used, the lowest effective dosage should be used for the shortest duration possible.

Acute Overdose

If an overdose is suspected, the patient should be taken to the doctor or hospital immediately. Symptoms of an overdose include nausea, vomiting, abdominal pain, drowsiness, convulsions, and sweating.

Contraindication

Cephradine is contraindicated in patients with a known hypersensitivity to cephalosporins or penicillins. It is also contraindicated in patients with severe renal or hepatic impairment, and in those who have had a previous episode of either anaphylactic or anaphylactoid reactions.

Use Direction

Cephradine should always be taken as prescribed by the doctor. The dosing frequency and duration of treatment should not be altered without consulting the healthcare provider.

Storage Condition

Cephradine should be stored at room temperature in a closed container, away from moisture and direct sunlight. Keep out of reach of children and pets.

Volume of Distribution

Cephradine has a volume of distribution of 0.3-0.6 L/kg indicating a low penetration into tissues.

Half Life

The elimination half-life of cefradine is in the range of 1-2 hours.

Clearance

Cephradine is mainly eliminated by the kidneys with an average clearance of 250mL/min.

Here you find in details version of Cephradine

Some Frequently Asked Questions About Cephradine

What is Cephradine?

Cephradine is a type of antibiotic medicine that is used to treat bacterial infections.

How does Cephradine work?

Cephradine works by preventing bacteria from forming cell walls, which are necessary for the bacteria to survive and grow.

What type of infections can Cephradine treat?

Cephradine is used to treat bacterial infections such as skin and soft tissue infections, urinary tract infections, and respiratory tract infections.

Who should not take Cephradine?

Cephradine should not be taken by people who are allergic to cephalosporin antibiotics. People with kidney, liver, or intestinal disease should consult a doctor before taking this medicine.

What are the possible side effects of Cephradine?

The most common side effects of Cephradine are nausea, vomiting, diarrhea, skin rash, and headache.

Is Cephradine safe to take during pregnancy?

Cephradine is generally considered safe to take during pregnancy, however it is recommended that pregnant women should consult their doctor before taking it.

What should I do if I experience any side effects from Cephradine?

If you experience any side effects, you should stop taking the medication and consult your doctor immediately.

How and when should I take Cephradine?

Cephradine should be taken with food or a full glass of water/milk. The amount and duration of treatment will depend on the type and severity of your infection.

What should I do if I miss a dose of Cephradine?

If you miss a dose of Cephradine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule.

Is it safe to consume alcohol while taking Cephradine?

It is not recommended to consume alcohol while taking Cephradine as it may increase the risk of side effects such as nausea, dizziness, drowsiness, and reduced alertness.

Can I take other medicines while taking Cephradine?

Some medicines may interact with Cephradine and it is recommended to consult your doctor before taking any other medication.

Can Cephradine be used for children?

Cephradine can be used for children but it is important to consult a doctor before giving this medicine to a child.

Are there any foods I should avoid while taking Cephradine?

No, you do not need to avoid any specific foods while taking Cephradine.

How long does it take for Cephradine to work?

It may take up to 2 weeks for Cephradine to work and start relieving symptoms.

Can I stop taking Cephradine once I start to feel better?

No, it is important to continue taking Cephradine until you have finished the course of medication prescribed by your doctor.

What should I do if I am taking Cephradine and experience a fever?

If you experience a fever while taking Cephradine, you should contact your doctor as soon as possible.

Does Cephradine interact with birth control pills?

Yes, Cephradine may interact with birth control pills. It is recommended to consult your doctor for advice.

Does Cephradine interact with other antibiotics?

Yes, some antibiotics may interact with Cephradine. It is recommended to consult your doctor for advice before taking any other medication.

Should I take Cephradine with food or on an empty stomach?

Cephradine should be taken with food or a full glass of water/milk.

Can Cephradine be used to treat a sore throat?

Yes, Cephradine is used to treat sore throat caused by bacterial infections.

Can I take Cephradine to prevent an infection?

No, Cephradine should not be taken as a preventative measure against infections.

Is Cephradine affected by hot weather?

No, Cephradine is not affected by hot weather.

Can Cephradine be taken with vitamin supplements?

Yes, Cephradine can be taken with vitamin supplements, however it is recommended to consult your doctor before taking any additional supplements.

What should I do if I experience an allergic reaction to Cephradine?

If you experience an allergic reaction to Cephradine, stop taking the medication and contact your doctor immediately.

Can I take Cephradine with antacids?

Yes, Cephradine can be taken with antacids, however it is recommended to consult your doctor for advice.

Can I take Cephradine if I am breastfeeding?

It is not recommended to take Cephradine while breastfeeding, however it is recommended to consult your doctor for advice.

Can I take Cephradine while menstruating?

Yes, you can take Cephradine while menstruating.

What should I do if I experience nausea after taking Cephradine?

If you experience nausea after taking Cephradine, it is recommended to consult your doctor for advice.

Can Cephradine interact with other medications?

Yes, some medications may interact with Cephradine and it is recommended to consult your doctor before taking any other medication.

What should I do if I experience vomiting after taking Cephradine?

If you experience vomiting after taking Cephradine, it is recommended to consult your doctor for advice.

Can I take Cephradine if I am diabetic?

Yes, Cephradine can be taken if you are diabetic, however it is recommended to consult your doctor for advice.

Can I take Cephradine if I have a kidney condition?

Yes, Cephradine can be taken if you have a kidney condition, however it is recommended to consult your doctor for advice.

Can I take Cephradine if I have a liver condition?

Yes, Cephradine can be taken if you have a liver condition, however it is recommended to consult your doctor for advice.

Is there any age restriction for taking Cephradine?

No, there is no age restriction for taking Cephradine, however it is recommended to consult your doctor for advice.

Can Cephradine cause dizziness?

Yes, Cephradine can cause dizziness, and it is recommended to consult your doctor if you experience this symptom.

Can Cephradine cause drowsiness?

Yes, Cephradine can cause drowsiness, and it is recommended to consult your doctor if you experience this symptom.

Can Cephradine cause dehydration?

Yes, Cephradine can cause dehydration, and it is recommended to consult your doctor if you experience this symptom.

Can Cephradine cause reduced alertness?

Yes, Cephradine can cause reduced alertness, and it is recommended to consult your doctor if you experience this symptom.

Can Cephradine cause a burning sensation?

Yes, Cephradine can cause a burning sensation, and it is recommended to consult your doctor if you experience this symptom.

Can Cephradine cause headaches?

Yes, Cephradine can cause headaches, and it is recommended to consult your doctor if you experience this symptom.

Can Cephradine cause stomach cramps?

Yes, Cephradine can cause stomach cramps, and it is recommended to consult your doctor if you experience this symptom.