Caltrate

Caltrate Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Caltrate is a brand name. Its generic name is Calcium Orotate Dihydrate.

Caltrate

Caltrate is a form of calcium salt that has been used as a dietary supplement. It is composed of calcium and orotic acid and is sometimes referred to as orotic acid calcium complex. It is a water-soluble mineral that is not found naturally in foods and must be ingested in supplemental form.

Introduction

Caltrate is a mineral form of calcium and orotic acid, sometimes referred to as orotic acid calcium complex, and is water-soluble. Studies have shown that the orotic acid helps with calcium absorption, making calcium orotate dihydrate an ideal calcium supplement for those who have difficulty absorbing other calcium supplements. It is not naturally found in foods and must be taken as a dietary supplement.

Uses For

Caltrate is used as a dietary supplement to help maintain bone density and to help prevent osteoporosis. It may also be recommended to strengthen bones and teeth, for bone growth, and for proper muscle and nerve function. It is an essential mineral for nerve transmission and muscle contraction. It plays key roles in multiple body systems including blood clotting, immune system, and hormone regulation.

Mechanism of Action

Caltrate works by supplying a readily available source of calcium and orotic acid to the body. The orotic acid helps increase the absorption of the calcium, which helps to support healthy bones, muscles, and nerves. Calcium also helps to regulate other bodily functions, such as blood clotting, hormones, and the immune system.

How Long Does it Take to Work?

Since Caltrate is a dietary supplement, it will depend on the person's individual body chemistry and how quickly they absorb the minerals. For most, it will usually take several weeks to start seeing the benefits of it.

Absorption

As a water-soluble mineral, Caltrate is readily absorbed in the gut. The addition of the orotic acid helps to increase the rate of absorption of the calcium. For some people, it may take several weeks to start seeing the full effects of the supplement.

Route of Elimination

Caltrate is eliminated from the body through waste, primarily through urine. The rate of elimination will depend on the individual and can vary. People who are taking the supplement for a longer period of time may have a higher rate of elimination.

Dosage

For adults and children over 12 years, the recommended dosage is 1000 to 1500 mg daily, taken with food, in divided doses. For children under 12 years, the dosage should be determined by a qualified healthcare professional. It is important to not exceed the recommended dosage as this can lead to serious side effects.

Administration

Caltrate should be taken orally, with food. It is best to spread the doses throughout the day, taking the supplement in two or three divided doses for optimal absorption. The supplement should be taken at the same time each day to ensure that the body is continually receiving a regular supply of calcium.

Side Effect

The most common side effects associated with Caltrate are gastrointestinal discomfort such as bloating, gas, and constipation. Other side effects may include headache, nausea, muscle pain and cramping, and fever. If any of these side effects persist or worsen, it is important to contact your healthcare provider.

Toxicity

Caltrate is considered to be a low toxicity substance. However, taking more than the recommended doses can lead to serious health risks such as kidney stones, dehydration, and an irregular heartbeat. It is important to speak to a healthcare professional before taking any supplement.

Precaution

It is important to speak to your healthcare professional before taking Caltrate. This supplement should be used cautiously in those with chronic kidney disease. Other precautions include not taking this supplement if you are pregnant, breastfeeding, or taking medications. Be sure to tell your doctor about all medications and supplements you are taking.

Interaction

Caltrate has the potential to interact with other medications, supplements, and herbs. It is important to tell your healthcare professional about any medications, supplements, and herbs you are currently taking before starting this supplement.

Disease Interaction

Caltrate may interact with certain diseases, especially those affecting the heart, kidneys, or gastrointestinal tract. It is important to speak to a healthcare provider before taking this supplement if you have a medical condition or disease.

Drug Interaction

Caltrate may interact with other drugs, both prescription and non-prescription medications. Some of these drugs include antacids, antibiotics, antifungal medications, laxatives, diuretics, and some chemotherapy drugs. It is important to tell your healthcare provider about all medications and supplements you are taking before starting this supplement.

Food Interactions

Caltrate may interact with certain foods, such as dairy, spinach, nuts, and chocolate. It is important to speak to a healthcare provider before taking this supplement to identify potential food interactions.

Pregnancy Use

Caltrate is not recommended for women who are pregnant or planning to become pregnant. It is important to speak to a healthcare professional before taking any supplement during pregnancy or when trying to become pregnant.

Lactation use

Caltrate is not recommended for women who are breastfeeding. It is important to consult with a healthcare professional before taking any supplement while breastfeeding.

Acute Overdose

Taking too much of Caltrate can lead to an acute overdose. Symptoms of an acute overdose may include nausea, vomiting, diarrhea, muscle weakness, confusion, coma, and seizures. If an overdose is suspected, it is important to seek medical attention immediately.

Contraindication

Caltrate should not be taken by people who have kidney disease or an inflammatory bowel disorder. It should also not be taken by people who are taking antacids, laxatives, or diuretics. It is important to speak to a healthcare provider before taking this supplement to determine if it is right for you.

Use Directions

Caltrate should be taken as directed by your healthcare professional. It is important to take this supplement with food, and it is best to spread the doses throughout the day. Do not take more than the recommended dosage as this can lead to serious side effects.

Storage Condition

Caltrate should be stored in a cool, dry place out of direct sunlight. It is important to keep the supplement away from heat and moisture. Do not store the supplement in the refrigerator or the freezer.

Volume of Distribution

Calcium orotate dihydrate is distributed well throughout the body and is found in saliva, bile, and urine. It is quickly absorbed in the gut and begins to circulate through the body.

Half Life

The half-life of Calcium orotate dihydrate is approximately 1.5 hours. It begins to be absorbed in the gut and is then distributed to other parts of the body.

Clearance

The clearance of Calcium orotate dihydrate is approximately 10 mL/min. It is quickly absorbed in the gut and then metabolized and eliminated from the body, primarily through the urine.

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Some Frequently Asked Questions About Caltrate