Brospan
Brospan Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Brospan is a brand name. Its generic name is Hyoscine Butylbromide.
etcIntroduction
Hyoscine butylbromide, also known as scopolamine butylbromide, is a medication used to treat various conditions such as motion sickness, cramps of the uterus and stomach muscles, and to reduce secretions from the salivary glands, respiratory tract, and intestines.Uses
Hyoscine butylbromide is used to treat motion sickness, cramps, and secretions from the salivary glands, respiratory tract, and intestines. It may also be used in the pre-operative and post-operative setting as an anti-emetic to prevent vomiting and other symptoms of nausea.Mechanism of Action
Hyoscine butylbromide works by inhibiting acetylcholine, a neurotransmitter responsible for stimulating muscles. This leads to blocking of parasympathetic nerve impulses to the salivary, respiratory, and gastrointestinal tracts, leading to decreased secretions in all three areas. This also helps to control motion sickness by decreasing the signals of nausea and vomiting.How Long Does It Take to Work?
The effects of hyoscine butylbromide usually start within 30 minutes and last up to 4-6 hours.Absorption
Hyoscine butylbromide is rapidly absorbed after oral administration.Route of Elimination
Hyoscine butylbromide is mostly eliminated through the kidneys as metabolites.Dosage and Administration
Hyoscine butylbromide is available in oral tablets or capsules. The dosage will depend on the individual’s condition and age. For motion sickness or pre or postoperative treatment, adults may take 2 to 4 tablets per day with meals and children may take 1 tablet per day. In the case of cramps, adults may take 2 tablets three times per day and children may take 1 tablet three times per day.Side Effect
The most common side effects of hyoscine butylbromide include dry mouth, blurred vision, drowsiness, dizziness, and constipation.Toxicity
Hyoscine butylbromide is a relatively safe medication with few toxic effects even in large doses. However, in cases where there is an overdose, the side effects can be very serious. Symptoms include restlessness, loss of vision, hallucinations, and convulsions.Precautions
Patients being treated with Hyoscine butylbromide should be monitored closely as it may increase the effects of alcohol and other central nervous system depressants. The elderly should use this medication with caution as they may be more sensitive to its effects.Interactions
Hyoscine butylbromide should not be taken with MAO inhibitors or muscle relaxants as this may increase the effects of these drugs. Additionally, there may be an increased risk of toxicity if taken with other medications, such as blood pressure medications, antihistamines, certain antibiotics, and antipsychotics.Disease Interactions
Hyoscine butylbromide should be used with caution in patients with certain medical conditions, including glaucoma, enlarged prostate, myasthenia gravis, respiratory depression, kidney or liver disease, psychiatric conditions, and bladder obstruction.Drug Interactions
Hyoscine butylbromide may interact with alcohol, narcotics, MAO inhibitors, muscle relaxants, certain antibiotics, and antipsychotics. Patients should also be aware that certain drugs, such as blood pressure medications, may also interact with hyoscine butylbromide.Food Interactions
Hyoscine butylbromide taken with food may be more effective than taken on an empty stomach.Pregnancy and Lactation Use
Hyoscine butylbromide should be used with caution during pregnancy and nursing mothers should not take this medication.Acute Overdose
Symptoms of an acute overdose include restlessness, delirium, blurred vision, peripheral cyanosis, respiratory depression, convulsions, and death if not treated immediately.Contraindications
Hyoscine butylbromide is contraindicated in patients with known hypersensitivity to the medication, and in patients with glaucoma and urinary blockages.Dose Directions
The dosage of Hyoscine butylbromide depends on the individual’s condition and age. For motion sickness or pre or postoperative treatment, adults may take 2 to 4 tablets per day with meals and children may take 1 tablet per day. In the case of cramps, adults may take 2 tablets three times per day and children may take 1 tablet three times per day.Storage Conditions
Hyoscine butylbromide should be stored at room temperature.Volume of Distribution
Hyoscine butylbromide is distributed mainly in the liver, spleen, kidneys and intestines.Half Life
The half-life of hyoscine butylbromide is about 16 hours.Clearance
Hyoscine butylbromide is mainly eliminated through the kidneys via renal clearance.Here you find in details version of Brospan
Some Frequently Asked Questions About Brospan
What is Brospan?
Brospan, also known as scopolamine butylbromide, is a medication used to relieve nausea, vomiting, vertigo and motion sickness.
What is the dosage of Brospan?
The usual adult dose range is 0.4 to 0.8 mg, administered intramuscularly or subcutaneously, or per rectum as needed.
Is Brospan safe for children?
Yes, Brospan is safe for children when used according to the dosage and directions provided by a physician.
Is Brospan habit forming?
No, there is no evidence to suggest that Brospan is habit-forming.
What are the side effects of Brospan?
The most common side effects of Brospan include dry mouth, blurred vision, dizziness, and drowsiness. Other less common side effects may include constipation, difficulty urinating, nausea, vomiting, and abdominal pain.
What should I do if I experience side effects while taking Brospan?
If you experience any side effects while taking Brospan, you should contact your doctor right away for further instructions.
Does Brospan interact with other medications?
Yes, Brospan may interact with certain medications and supplements, including anticholinergics, antihistamines, sedatives, drugs for sleep, and drugs used to treat depression, among others. Therefore, it is important to inform your doctor of all medications and supplements you are taking before starting Brospan.
Can Brospan be used during pregnancy?
No, Brospan should not be used during pregnancy as it may cause serious harm to the unborn baby.
Should I avoid driving while taking Brospan?
Yes, since Brospan may cause drowsiness, you should avoid driving or operating machinery while taking it.
What should I do if I miss a dose of Brospan?
If you miss a dose of Brospan, take it as soon as you remember unless it is almost time for your next dose. Do not take a double dose to make up for the missed dose.
What should I do if I overdose on Brospan?
If you or someone else has taken an overdose of Brospan, seek medical attention immediately. Do not wait for symptoms to appear.
Can I drink alcohol while taking Brospan?
No, you should avoid drinking alcohol while taking Brospan as it may increase the risk of side effects.
Is Brospan available over the counter?
No, Brospan is a prescription medication and is not available over the counter.
Can Brospan be used for long-term treatment?
No, Brospan should not be used for long-term treatment and should only be used as needed for short periods.
Is Brospan available in generic form?
No, Brospan is not available in generic form.
Can Brospan be used to treat motion sickness?
Yes, Brospan is used to treat nausea, vomiting, vertigo and motion sickness.
How long does it take for Brospan to start working?
Brospan is usually given as an injection, and it usually begins working about 15 minutes after administration.
How long does the effect of Brospan last?
The effects of Brospan usually last up to 6 hours.
What is the half-life of Brospan?
The half-life of Brospan is about 3 to 4 hours.
What is the storage condition of Brospan?
Brospan should be stored at room temperature away from light and moisture.
What is the difference between Brospan and Hyoscine Hydrobromide?
Brospan is an anticholinergic medication used to treat nausea, vomiting, vertigo and motion sickness. Hyoscine Hydrobromide is also an anticholinergic medication used to treat gastrointestinal disorders, such as irritable bowel syndrome.
Is Brospan safe for elderly use?
Yes, Brospan is safe for elderly use when used according to the dosage and directions provided by a physician.
Is Brospan used to relieve dizziness?
Yes, Brospan is used to relieve dizziness caused by vertigo as well as motion sickness.
Can Brospan be used to treat migraines?
No, Brospan is not specifically used to treat migraines. However, it can be used to relieve nausea which is one of the symptoms of migraines.
Does Brospan have antispasmodic properties?
Yes, Brospan has antispasmodic properties that may be used to treat gastrointestinal disorders.
What is the chemical structure of Brospan?
Brospan is a synthetic compound of the anticholinergic benzoic acid family. Its chemical structure is C17H23NO5.
Will Brospan make me sleepy?
Yes, Brospan can cause drowsiness and it is important to avoid activities that require alertness, such as driving or operating machinery, while taking it.
Are there studies that show Brospan is effective for motion sickness?
Yes, several studies have been conducted that demonstrate the effectiveness of Brospan in reducing nausea and vomiting associated with motion sickness.
Are there differences in dosage depending on age and weight?
Yes, the dosage of Brospan may vary depending on the age and weight of the patient, so it is important to follow the instructions of a physician when taking this medication.
What are the most common brands of Brospan?
The most common brands of Brospan include Scopacin, Dialose, and Buccinal.
Is Brospan safe to use long-term?
No, Brospan should not be used long-term as it may cause serious side effects. It should only be used as needed for short periods.
Does Brospan cause serious side effects?
Yes, although rare, Brospan can cause serious side effects such as hallucinations, confusion, fast or slow heart rate, trouble breathing, and seizures. If you experience any of these, seek medical attention immediately.
What should I do if I experience an allergic reaction to Brospan?
If you experience any symptoms of an allergic reaction to Brospan, such as rash, itching, hives, difficulty breathing, or swelling, seek emergency medical attention right away.
Can Brospan be used with other antiemetics?
Yes, Brospan can be used with other antiemetics such as prochlorperazine or metoclopramide, but it is important to consult your doctor before combining any medications.
Are there any foods or beverages to avoid while taking Brospan?
Yes, you should avoid alcohol, grapefruit juice, and multivitamins while taking Brospan.
What are the long-term effects of Brospan use?
The long-term effects of Brospan use are not known, and it should only be used for short periods as needed. If you are using it for long periods, you should consult your doctor to monitor for any side effects.