Bongel

Bongel Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Bongel is a brand name. Its generic name is Cetalkonium Chloride + Choline Salicylate.

Introduction

Cetalkonium Chloride (CTC) and Choline Salicylate (CS) are two active pharmaceutical ingredients widely used in the medical industry. CTC is an antiseptic compound that helps reduce inflammation, while CS is an analgesic that aids in relieving pain. Together, CTC and CS are used to treat a wide variety of common infections and minor injuries.

Uses

Cetalkonium Chloride and Choline Salicylate are commonly used to provide symptomatic relief from itching, burning, pain, and discomfort associated with minor cuts, abrasions, and insect bites. It is also effective in the treatment of inflammations due to infection, earaches, sunburn, and other hot, irritated skin conditions. Additionally, it has been used to reduce the swelling of sprains and strains and to treat minor cases of Acne and Dyshidrosis.

Mechanism of Action

Cetalkonium chloride is a cationic quaternary ammonium compound, meaning that its positive charges interact with negatively charged bacterial membranes and cause them to rupture. This disruption of the cell membrane leads to cell death and effectively treats bacterial infections. Choline salicylate will provide anti-inflammatory and analgesic effect.

How Long Does it Take to Work?

Cetalkonium Chloride and Choline Salicylate generally start working immediately or within a few minutes, and the effects can last for several hours. Depending on the severity of the infection or inflammation, the treatment can require either a single application or multiple applications over a period of a few days or weeks.

Absorption

Cetalkonium Chloride and Choline Salicylate have a very low potential for absorption into the bloodstream, meaning that most of the drug remains on the skin surface.

Route of Elimination

Cetalkonium Chloride and Choline Salicylate will be eliminated through the skin over a period of time.

Dosage

The typical dosage for an adult is 2 to 3 milliliters of the CTC/CS solution applied to the affected area up to 3 times a day as needed. The dosage may vary for certain medical conditions or other medications used in combination.

Administration

Cetalkonium Chloride and Choline Salicylate can be applied topically as a liquid solution to the skin or to the affected area. It should not be taken orally or by injection. Care should be taken to avoid contact with eyes, mucous membranes, and sensitive skin areas.

Side Effects

Cetalkonium Chloride and Choline Salicylate are generally well tolerated when applied topically. Possible side effects may include burning, stinging, or itching at the application site. In the event of irritation, discontinue use and consult a physician.

Toxicity

Cetalkonium Chloride and Choline Salicylate are largely considered to be nontoxic due to their low potential for systemic absorption when applied topically.

Precautions

Cetalkonium Chloride and Choline Salicylate should not be used on broken or damaged skin. It should also be avoided in cases of known hypersensitivity or allergy to any of its components.

Interactions

No known drug interactions have been reported with the use of Cetalkonium Chloride and Choline Salicylate.

Disease Interactions

Cetalkonium Chloride and Choline Salicylate should be used cautiously in individuals with known kidney or liver dysfunction, as well as those with asthma or allergies.

Drug Interactions

No known drug interactions have been reported with the use of Cetalkonium Chloride and Choline Salicylate.

Food Interactions

No known food interactions have been reported with the use of Cetalkonium Chloride and Choline Salicylate.

Pregnancy Use

Cetalkonium Chloride and Choline Salicylate are not recommended for use in pregnant women, as safety has not been established.

Lactation Use

Cetalkonium Chloride and Choline Salicylate should not be used by nursing mothers, as safety has not been established.

Acute Overdose

An acute overdose of Cetalkonium Chloride and Choline Salicylate is unlikely due to its low systemic absorption. However, any overdoses should be managed symptomatically.

Contraindications

Cetalkonium Chloride and Choline Salicylate should not be used in individuals with a known hypersensitivity or allergy to any of its active ingredients.

Use Directions

Cetalkonium Chloride and Choline Salicylate should be applied to the affected area up to 3 times a day as needed. Care should be taken to avoid contact with delicate areas such as eyes, mucous membranes, and sensitive skin areas.

Storage Conditions

Cetalkonium Chloride and Choline Salicylate should be stored at room temperature, away from heat, light, and moisture.

Volume of Distribution

The volume of distribution of Cetalkonium Chloride and Choline Salicylate is unknown, as it is unlikely to be significantly systemically absorbed.

Half-Life

The half-life of Cetalkonium Chloride and Choline Salicylate is unknown, as it is unlikely to be significantly systemically absorbed.

Clearance

The clearance of Cetalkonium Chloride and Choline Salicylate is unknown, as it is unlikely to be significantly systemically absorbed.

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