Bactroban

Bactroban Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Bactroban is a brand name. Its generic name is Mupirocin.

Bactroban

Bactroban is an antibiotic approved for topical and systemic use in humans.

Uses For

Bactroban is commonly used to treat and prevent skin infections caused by bacteria, such as Staphylococcus aureus (MRSA). It is also used to treat superficial, cutaneous, and impetigo bacterial infections, as well as being used in the eradication of nasal carriage of methicillin-resistant organisms.

Mechanism of Action

Bactroban works by inhibiting bacterial protein synthesis. It affects bacterial cells by binding to bacterial isoleucyl transfer RNA synthetase, resulting in the suppression of protein synthesis by bacterial ribosomes.

How Long Does It Take to Work?

Bactroban typically begins to work within several days. For skin infections, topical treatment may take up to 2 weeks for infection to fully resolve.

Absorption

Bactroban is partially absorbed through the skin into the bloodstream following topical application. The rate and amount of absorption are variable and dependent on the area of application.

Route of Elimination

Bactroban is primarily eliminated through the bile. It is also metabolized by the liver and excreted in the feces.

Dosage

The dosage of mupirocin cream or ointment depends on the severity of the skin infection. Adults should typically apply a thin layer of the product to the affected area every 3 to 4 hours, and not exceed 8 doses per day. For nasal application, adults and children over 12 years should apply a single dose of mupirocin cream to the nostrils, not exceeding 4 times daily.

Administration

Bactroban cream or ointment should be applied to the affected area of the skin or inside the nostrils. It should be applied in a thin layer, gently massaged in, and not be bandaged or covered. For treating impetigo, the affected area should also be washed with warm water and soap twice a day.

Side Effects

Common side effects of mupirocin include stinging, burning, itching, and redness at the application site. More serious reactions, such as severe allergic reactions, are possible, but rare. If any of these occur, ask a doctor for advice.

Toxicity

The topical administration of mupirocin is well-tolerated in humans, with side effects generally being limited to localized effects such as skin irritation. While systemic absorption is possible, it is very low and unlikely to result in toxicity.

Precautions & Warnings

Bactroban should not be used if allergic to any of its components, or if infections that are not caused by bacteria are present. In addition, people who are immunocompromised or taking antibiotics should use caution when applying mupirocin.

Interactions

Bactroban has no reported drug interactions, however, other medications may interact with mupirocin. If using any other medicines, it is best to consult with a doctor before using mupirocin.

Disease Interactions

Patients with a history of hypersensitivity reactions to other topical antibiotics may have an increased risk of developing an allergic reaction to mupirocin. Therefore, caution should be exercised when using mupirocin in patients with a known history of sensitivity.

Drug Interactions

Bactroban has no known drug interactions.

Food Interactions

Bactroban does not interact with food.

Pregnancy Use

Bactroban has been classified as category B by the Food and Drugs Administration (FDA) and is generally believed to be safe for use during pregnancy. Although there have been no reported adverse effects in humans used during pregnancy, it is best to consult with a doctor before using during pregnancy.

Lactation Use

Bactroban is not known to be harmful during lactation, but it is not known if it passes into breast milk and may have an effect on a nursing infant. Therefore, caution should be used when using mupirocin while breastfeeding.

Acute Overdose

The symptoms of an acute overdose from topical administration of mupirocin are not reported. In general, an oral ingestion of mupirocin can lead to gastrointestinal irritation or an allergic reaction.

Contraindication

Bactroban is contraindicated in individuals who have a known hypersensitivity to any of the components of mupirocin ointment.

Use Direction

Bactroban ointment or cream should be applied as a thin layer to a clean and dry skin area, and gently massaged into the skin in the direction of hair growth. It should not be put over a bandage or covered. The area should be washed with soap and warm water twice daily if treating impetigo.

Storage Condition

Bactroban should be stored at room temperature between 15°C to 25°C (59°F to 77°F). It should be kept away from light, heat, and moisture.

Volume of Distribution

The volume of distribution of mupirocin is not known.

Half-Life

The half-life of mupirocin is not known.

Clearance

The clearance of mupirocin is not known.

Here you find in details version of Bactroban

Some Frequently Asked Questions About Bactroban

What is Bactroban ointment?

Bactroban ointment is an antibiotic topically used to treat skin infections caused by certain bacteria. It works by killing bacteria or preventing their growth. It is primarily used for the treatment of impetigo, or pimple-like sores. Bactroban ointment may also be used for other purposes as determined by a doctor.

Is Bactroban a steroid?

No, Bactroban is not a steroid. It is an antibiotic ointment used to treat skin infections.

How should Bactroban be applied?

Bactroban should be applied two or three times a day over the affected area of skin. It should be applied with gentle pressure so that the ointment is absorbed into the skin. The ointment should not be rubbed into the skin, but allowed to remain until it is absorbed on its own.

How long does it take for Bactroban to work?

It may take anywhere from a few days to a week for Bactroban to begin working on the affected area of skin. If improvement in the condition is not seen within this time frame, or if the condition worsens, a doctor should be consulted.

Is Bactroban safe for children?

Yes, Bactroban is generally safe for use in children, when used as directed. However, as with any medication, it is important to consult a doctor for appropriate dosage and safety information.

Is Bactroban ointment safe to use while pregnant?

Generally, Bactroban ointment is considered safe for use in pregnancy. However, it is important to consult a doctor for guidance on its use and safety during pregnancy.

What should I do if I experience an allergic reaction to Bactroban?

If you experience any signs of an allergic response such as itching, swelling, or difficulty breathing, you should stop using the ointment immediately and seek medical attention.

Is Bactroban the same as neomycin?

No, Bactroban is not the same as neomycin. Bactroban is an antibiotic topically used to treat skin infections, while neomycin is an antibiotic typically used to treat bacterial infections of the digestive system.

How long can Bactroban be used?

Bactroban should only be used for the duration of time specified by the doctor. Typically, Bactroban ointment is used for no more than 10 days.

Is Bactroban ointment available over-the-counter?

No, Bactroban ointment is only available with a prescription from a doctor.

Does Bactroban treat acne?

No, Bactroban ointment is used to treat skin infections, not acne.

Is Bactroban effective in treating MRSA?

Bactroban is effective in treating MRSA, or methicillin-resistant Staphylococcus aureus, when applied topically to the affected area of skin.

Does Bactroban ointment need to be refrigerated?

No, Bactroban ointment does not need to be refrigerated. It should be stored in a cool, dry place, away from direct sunlight.

How long does Bactroban stay in the body?

Bactroban is not known to stay in the body for particular periods of time. Once it is absorbed into the skin, it starts to work.

What are the side effects of using Bactroban?

Some side effects of using Bactroban may include burning, stinging, redness, or itching at the application site. If these or other symptoms persist or worsen, you should consult a doctor immediately.

What are the precautions for using Bactroban?

When using Bactroban, you should avoid contact with the eyes, nose, and mouth. If contact does occur, rinse affected area immediately with water. Avoid covering the treated area with a bandage or tight clothing, as this may result in increased irritation of the skin.

What should I avoid while using Bactroban?

You should avoid using other topical medication on the same area of skin where you are using Bactroban. Avoid exposing the affected area of skin to direct sunlight, and do not use cosmetics or additional skincare products on the area of skin being treated.

Should I apply sunscreen before using Bactroban?

Yes, you should apply a sunscreen with a minimum SPF of 15 before applying Bactroban. This will help prevent the skin from becoming irritated or further damaged when exposed to the sun.

What happens if I miss a dose of Bactroban?

If you miss a dose of Bactroban, you should apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

What should I do if I accidentally swallow Bactroban?

If you accidentally swallow Bactroban ointment, you should drink plenty of water, contact your doctor and seek medical help as soon as possible.

Can I use Mupircoin ointment on my face?

Yes, you can use Bactroban ointment on your face, however you should avoid contact with the eyes and mouth while doing so. It is best to consult a doctor if you are considering using Bactroban on your face.

Is Bactroban effective for ringworm infections?

Yes, Bactroban has been shown to be effective in treating ringworm infections when used topically.

How soon after using Bactroban can I return to my usual activities?

You should wait until any irritation caused by applying Bactroban has subsided before returning to your normal activities. If the irritation persists, consult your doctor before resuming any activities.

What does Bactroban treat?

Bactroban is an antibiotic topically used to treat skin infections caused by certain bacteria. It is primarily used for the treatment of impetigo, or pimple-like sores.

Can I use Bactroban more than twice a day?

No, you should not use Bactroban more than twice a day. Overuse of Bactroban may lead to an increased risk of skin irritation, and the development of resistant bacteria.

What should I do if Bactroban does not seem to be working?

If Bactroban does not seem to be working, you should consider switching to another antibiotic or topical medication. It is also important to consult a doctor as soon as possible if the condition does not improve, or if it worsens.

Can Bactroban be used with other medications?

Yes, Bactroban can be used with other medications, however it is important to consult a doctor before doing so. Some medications may interfere with the efficiency and effectiveness of Bactroban.

What are the common uses of Bactroban?

The common uses of Bactroban are for the treatment of skin infections, such as impetigo, folliculitis, and boils. It is also used for the treatment of MRSA, or methicillin-resistant Staphylococcus aureus.

Does Bactroban cause an increase in blood pressure?

No, Bactroban does not cause an increase in blood pressure. However, if you are currently taking medications to lower blood pressure, you should consult a doctor before using Bactroban ointment.

Is Bactroban safe to use for long-term treatment?

No, Bactroban should not be used for long-term treatment. It should only be used for the duration specified by the doctor, typically no more than 10 days.

Will Bactroban help with eczema?

No, Bactroban is not usually used to treat eczema. It should not be used to treat any skin condition without consulting a doctor first.

What should I do if I forget to apply Bactroban?

If you forget to apply Bactroban, you should apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

What happens if Bactroban gets in my eyes?

If Bactroban gets in your eyes, rinse the affected area with plenty of water. If irritation or blurred vision persists, contact your doctor as soon as possible.

Can I use Bactroban on open wounds?

No, Bactroban should not be used on open wounds. You should seek medical attention for any open wounds before using Bactroban ointment.

Can I use Bactroban on a baby?

Yes, Bactroban can be used on a baby, however it is important to consult a doctor for the appropriate dosage. It is also important to ensure that the baby does not touch or rub their eyes after using Bactroban ointment.

Is Bactroban ointment used to treat yeast infections?

No, Bactroban ointment is not used to treat yeast infections. It is an antibiotic used to treat bacterial skin infections.

How will I know if my skin infection has been successfully treated by Bactroban?

If your skin infection has been successfully treated with Bactroban, the area of skin should begin to improve within a few days. If there is no improvement after a week of using the ointment, you should consult a doctor.

Should I wash my hands after applying Bactroban?

Yes, you should wash your hands after applying Bactroban ointment, as it may contain bacteria or other germs that could lead to infection.

Can Bactroban be used on cuts?

No, Bactroban should not be used on cuts or other irritated areas of skin. You should seek medical attention for any cuts or open wounds before using Bactroban ointment.

Do I need to apply a bandage over the area of skin I applied Bactroban?

No, you should not apply a bandage over the area of skin where you applied Bactroban. Covering the area with a bandage or tight clothing may result in increased irritation of the skin.

Can I use Bactroban on my genitals?

It is not recommended to use Bactroban on the genitals as it may cause irritation. If you have a skin infection in the genital area, it is best to consult a doctor for appropriate treatment.

Can Bactroban be used to treat a cold?

No, Bactroban is not effective in treating colds. It is used to treat bacterial skin infections only.

Can Bactroban be used in combination with other antibiotics?

Yes, Bactroban can be used in combination with other antibiotics, however it is important to first consult a doctor or healthcare provider before doing so.

Does Bactroban ointment have any drug interactions?

Yes, Bactroban ointment may interact with certain medications, such as probenecid, tetracyclines, and certain beta-blockers