Azelastinum

Azelastinum, a brand name for a formulation containing essential Azelastine, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Azelastinum, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.

Azelastinum - Overview

Azelastinum is a prescription medication used to prevent and treat the symptoms of seasonal and year-round allergic rhinitis, or hay fever, and to prevent itching of the eyes caused by allergies. It is available in an oral form, eye drops, and nasal spray.

Uses For Azelastinum

Azelastinum is used to prevent and treat the symptoms of seasonal and year-round allergic rhinitis, or hay fever, and to prevent itching of the eyes caused by allergies. It is also used to prevent and treat itching of the eyes related to allergic conjunctivitis.

Mechanism of Action

Azelastinum works by acting on histamine receptors in the body. Histamine is a naturally occurring chemical compound that is involved in allergic reactions. Azelastinum works by blocking the action of the histamine and preventing it from causing allergic reactions.

How Long Does It Take to Work?

Azelastinum typically takes effect within a few minutes of administration and can last up to 24 hours.

Absorption

Azelastinum is well absorbed in the body after oral, inhalation, or topical administration.

Route of Elimination

Azelastinum is primarily metabolised in the liver by CYP450 and then excreted in the urine and faeces.

Dosage and Administration

Azelastinum is available in tablet, oral suspension, eyedrop, and nasal spray forms. The appropriate dosage and administration depends on the form of azelastine being used and the medical condition being treated. For oral tablets, the usual dose is 1-2 tablets taken twice a day. For oral suspension, the usual dose is 2-4 milliliters of oral suspension taken twice a day, after meals. For eye drops, the usual dose is 2-4 drops into the affected eye(s) twice a day. For nasal spray, the usual dose is 2 sprays in each nostril twice a day.

Side Effects

Common side effects of azelastine include drowsiness, dry mouth, fatigue, nasal irritation, and bitter taste in the mouth. Contact your doctor if any of these effects worsen or persist.

Toxicity

Azelastinum has low toxicity when used at the recommended doses.

Precautions

Azelastinum may cause drowsiness, so use caution before performing activities that require alertness, such as driving or operating heavy machinery. It is also important to tell your doctor about any other medications or supplements you are taking before beginning treatment with azelastine.

Interactions

Azelastinum may interact with other medications, causing unpredictable changes in effects or side effects. Therefore, it is important to tell your doctor about any medications or supplements you are taking before beginning treatment with azelastine.

Disease Interactions

Azelastinum may interact with certain diseases, such as renal impairment, liver disease, urinary retention, or asthma. It is important to tell your doctor if you have any of these conditions before beginning treatment with azelastine.

Drug Interactions

Azelastinum may interact with certain drugs, such as anticholinergics, MAO inhibitors, or tricyclic antidepressants. It is important to tell your doctor if you are taking any of these medications before beginning treatment with azelastine.

Food Interactions

Azelastinum may interact with certain foods, such as caffeine, grapefruit, or licorice. It is important to tell your doctor if you are consuming any of these foods before beginning treatment with azelastine.

Pregnancy Use

Azelastinum should be used during pregnancy only if clearly needed. It is important to discuss the risks and benefits of its use with your doctor before beginning treatment.

Lactation Use

Azelastinum is not recommended for use during lactation. It is important to discuss the risks and benefits of its use with your doctor before beginning treatment.

Acute Overdose

If an overdose of azelastine is suspected, contact your local poison control center or emergency room immediately.

Contraindication

Azelastinum is contraindicated in patients who are allergic to any of the active ingredients or any of the inactive ingredients.

Use Direction

It is important to follow the exact dosing instructions provided by your doctor. Do not increase the dose or frequency of azelastine without consulting your doctor.

Storage Condition

Azelastinum should be stored at temperatures below 30°C (86°F).

Volume of Distribution

The volume of distribution of azelastine is 0.39 L/kg.

Half Life

The half life of azelastine is 5-11 hours.

Clearance

The clearance of azelastine is 0.38 L/min/kg.

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