Avodil VL

Avodil VL Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Avodil VL is a brand name. Its generic name is Amlodipine + Valsartan.

Introduction

Avodil VL is an antihypertensive medication that is used to treat hypertension. It is a combination of the calcium channel blocker Amlodipine and the angiotensin II receptor blocker Valsartan.

Uses for

Avodil VL is used to treat mild or moderate hypertension by lowering blood pressure and preventing associated complications such as stroke and cardiovascular disease.

Mechanism Of Action

Avodil VL works by blocking calcium channels in the blood vessels, causing them to relax and decrease blood pressure. Valsartan blocks the action of Angiotensin II, which normally causes the narrowing of certain blood vessels, and decreases blood pressure. Valsartan also increases the amount of circulating blood volume.

How Long Does It Take To Work

The effects of Avodil VL can be seen within two weeks of taking the medication, and it will normally reach its full effect within four to eight weeks.

Absorption

Amlodipine is readily absorbed from the gastrointestinal tract and reaches maximal levels within 2 to 4 hours. Valsartan is also absorbed rapidly and peak effects occur 1-2 hours after administration.

Route Of Elimination

Avodil VL is eliminated partly by the kidneys and partly by the intestines.

Dosage

The recommended adult starting dose of Avodil VL is amlodipine 5mg/valsartan 160 mg once a day with or without food. Dosage may be increased as necessary. Maximum recommended dose is amlodipine 10mg/valsartan 320mg once a day.

Administration

Avodil VL should be taken orally with or without food once daily. Swallow the tablet whole and do not chew or break it.

Side Effects

Side effects of Avodil VL may include headache, dizziness, fatigue, nausea, abdominal pain, diarrhea.

Toxicity

Avodil VL is not considered toxic. However, the maximum daily recommended dose should not be exceeded and it should not be taken with grapefruit or grapefruit juice.

Precautions

Patients using Avodil VL should be monitored for any signs or symptoms of fluid accumulation, such as swelling of the ankles or feet, or shortness of breath. Patient should also inform their provider if they have a history of liver or kidney disease, heart disease, or if they have been prescribed diuretics.

Interactions

Avodil VL can interact with other medications, such as diuretics, angiotensin-converting enzyme inhibitors, potassium-sparing diuretics, potassium supplements, and birth control pills.

Disease Interactions

Avodil VL should not be used in patients with anuria, aortic stenosis, or severe hepatic impairment.

Drug Interactions

Avodil VL can interact with other drugs, such as diuretics, angiotensin-converting enzyme inhibitors, potassium-sparing diuretics, potassium supplements, and birth control pills.

Food Interactions

Avodil VL should not be taken with grapefruit or grapefruit juice, as grapefruit may interfere with the absorption of the medication.

Pregnancy Use

Avodil VL should not be used during pregnancy unless the benefit outweighs the risk.

Lactation Use

Avodil VL is not recommended for use in nursing mothers.

Acute Overdoses

Patients who have taken an overdose of Avodil VL should seek medical help as soon as possible. Symptoms of overdose may include hypotension, dizziness, and confusion.

Contraindication

Avodil VL is contraindicated in patients with anuria, aortic stenosis, or severe hepatic impairment.

Use Direction

Avodil VL should be taken once daily as prescribed by your doctor. Take the medication with or without food. Swallow the medicine whole, do not chew or break it.

Storage Condition

Avodil VL should be stored at room temperature and in a tight, light-resistant container.

Volume Of Distribution

Amlodipine+Valsartan has a volume of distribution of 118L.

Half Life

Amlodipine has a half-life of approximately 75 hours and Valsartan has a half-life of approximately 6 hours.

Clearance

Amlodipine+Valsartan is eliminated mainly by cytochrome P450 enzyme system in the liver, with a smaller portion excreted unchanged in the urine.

Here you find in details version of Avodil VL

Some Frequently Asked Questions About Avodil VL

What is Avodil VL?

Avodil VL is a combination medicine used to treat high blood pressure (hypertension). It contains two different medicines which help lower blood pressure: amlodipine and valsartan. Amlodipine is a calcium channel blocker that works by relaxing the muscles in your blood vessels to help lower your blood pressure. Valsartan is an angiotensin II receptor blocker that works by blocking the action of certain chemicals in your body that tighten your blood vessels, causing your blood pressure to go up.

How do I take Avodil VL?

Avodil VL should be taken as prescribed by your doctor. The usual starting dose for adults is 5 mg/160 mg, taken once daily. Your doctor may increase your dose if needed.

What are the possible side effects of Avodil VL?

Common side effects include dizziness, headache, low blood pressure, fatigue, nausea, diarrhea, muscle cramps, and decreased heart rate. Less common side effects can include skin rash, joint pain, increased urination, decreased kidney function, chest pain, and heart failure. Talk to your doctor if you experience any of these side effects while taking Avodil VL.

What should I do if I forget to take Avodil VL?

If you miss a dose, take it as soon as you remember. If it is close to the time of the next dose, skip the missed dose and take your next dose at the regular time. Do not take a double dose of Avodil VL.

Can I take Avodil VL while pregnant?

It is not recommended that you take Avodil VL while pregnant. Talk to your doctor if you are pregnant or planning to become pregnant while taking Avodil VL.

Can I take Avodil VL with other medications?

It is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Avodil VL and affect how it works, so let your doctor know about all the medications you take.

What should I know before taking Avodil VL?

Before taking Avodil VL, tell your doctor about all your medical conditions, including if you have a history of heart problems, kidney disease, liver disease, are pregnant or planning to become pregnant, or if you are breastfeeding. Also tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Should I avoid taking other medications with Avodil VL?

No, however it is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Avodil VL and affect how it works, so your doctor needs to know about all the medications you take.

Does Avodil VL cause weight gain?

Weight gain has been reported in people taking Avodil VL. Tell your doctor if you are experiencing any changes in your weight while taking Avodil VL.

Is Avodil VL safe to take for a long time?

Avodil VL is generally safe to take for a long time, however, it is important to talk to your doctor about any risks or concerns you may have. Your doctor will be able to discuss the benefits and risks for you.

Should I take Avodil VL in the morning or at night?

Avodil VL can be taken either in the morning or at night. It is best to take the medication at the same time each day to keep a consistent level in your blood. Talk to your doctor about the best time for you to take Avodil VL.

What are the common side effects of Avodil VL?

Common side effects include dizziness, headache, low blood pressure, fatigue, nausea, diarrhea, muscle cramps, and decreased heart rate. Less common side effects can include skin rash, joint pain, increased urination, decreased kidney function, chest pain, and heart failure. Talk to your doctor if you experience any of these side effects while taking Avodil VL.

What should I do if I experience side effects from Avodil VL?

If you experience any side effects from Avodil VL, talk to your doctor or pharmacist. They may be able to adjust your dose or suggest alternatives. It is also important to tell your doctor about any other medications you are taking, as they can also cause side effects.

Can I drink alcohol while taking Avodil VL?

Alcohol can increase the side effects of Avodil VL. It is best to talk to your doctor about drinking alcohol while taking this medicine. If you decide to drink, do so in moderation.

Can I take a diuretic with Avodil VL?

A diuretic may be taken with Avodil VL if needed. Your doctor will be able to determine if a diuretic is necessary for your condition.

Are there any other medications I should avoid while taking Avodil VL?

There are certain medications that should be avoided while taking Avodil VL, including other angiotension-converting enzyme (ACE) inhibitors, angiotension-II receptor blockers (ARBs), calcium channel blockers (CCBs), potassium-sparing diuretics, trimethoprim-sulfamethoxazole, and non-steroidal anti-inflammatory drugs (NSAIDs). Check with your doctor or pharmacist to make sure your medications are safe to take with Avodil VL.

What should I do if I experience an allergic reaction to Avodil VL?

If you experience any signs of an allergic reaction, including hives, itching, skin rash, difficulty breathing, or swelling of your face, lips, tongue, or throat, seek medical attention immediately. Stop taking Avodil VL and tell your doctor right away.

What happens if I overdose on Avodil VL?

If you think you or someone else has overdosed on Avodil VL, call 911 or your local poison control center right away. Symptoms of an overdose may include severe dizziness, slow heartbeat, confusion, difficulty breathing, and fainting.

Are there any foods or drinks I should avoid while taking Avodil VL?

Alcohol and caffeine can increase the side effects of Avodil VL. Avoid drinking large amounts of caffeine-containing beverages (e.g., coffee, tea, cola) or alcohol while you are taking this medication. Talk to your doctor about your diet and medications, as certain foods may interact with them.

Can Avodil VL be used to treat other conditions?

Avodil VL is mostly used to treat high blood pressure (hypertension). It may be used off-label to treat other conditions, however, only your doctor can determine if this is appropriate for your condition. Speak with your doctor about any other conditions you may have and if Avodil VL is an appropriate treatment.

Will Avodil VL help lower my blood pressure?

Avodil VL is used to treat high blood pressure (hypertension). This medication can help lower your blood pressure over time. Follow your doctor's instructions and report any changes in your blood pressure to your doctor.

How quickly will I notice a difference after taking Avodil VL?

The effects of Avodil VL may take several weeks to become evident. You may begin to notice a lower blood pressure within a few weeks. Your doctor can monitor your blood pressure during treatment and adjust your dose if necessary.

Can I take Avodil VL if I have a history of heart problems?

Avodil VL can be used for people with a history of heart problems, however, your doctor may adjust your dose or use other medications to help control your symptoms. Your doctor will be able to determine the best treatment plan for you.

Will I need to have regular blood tests while taking Avodil VL?

You may need to have regular blood tests while taking Avodil VL. Your doctor will be able to determine if regular blood tests are necessary. Tell your doctor if you experience any changes in your blood pressure while taking Avodil VL.

Can I take other medications with Avodil VL?

It is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Avodil VL and affect how it works, so let your doctor know about all the medications you take.

What should I do if I experience dizziness while taking Avodil VL?

Dizziness is a common side effect of Avodil VL. If you experience dizziness while taking this medication, contact your doctor. Avoid driving, operating machinery, or performing other hazardous activities until the dizziness passes.

Should I take Avodil VL with food?

Avodil VL can be taken with or without food. It is best to take the medication at the same time each day to keep a consistent level in your blood. Talk to your doctor about the best time for you to take Avodil VL.

Can Avodil VL be used to treat heart failure?

Avodil VL may be used off-label to treat certain conditions, such as heart failure. Your doctor will be able to determine if this is an appropriate treatment for your condition.

Can Avodil VL be used in children?

Avodil VL is not indicated for use in children. Consult your doctor if you are considering treating a child with this medication.

Does Avodil VL lower cholesterol?

Avodil VL does not directly lower cholesterol. However, lower blood pressure can help improve cholesterol levels. If you are looking to lower your cholesterol, it is important to talk to your doctor about lifestyle changes, medications, and other treatments.

Does Avodil VL cause hair loss?

Hair loss is not a common side effect of Avodil VL. However, it has been reported in some people taking this medication. Talk to your doctor if you experience any changes in your hair while taking this medication.