Asmaloc SR Tablet (Sustained Release)

Brand Name: Asmaloc SR
Generic: Theophylline
Weight: 400 mg
Type: Tablet (Sustained Release)
Therapeutic Class: Theophylline & related drugs
Manufacturer: Sharif Pharmaceuticals Ltd.
Price: 4.17
Last Updated: 2020-11-22 18:15:00

Asmaloc SR Tablet (Sustained Release) Uses

Asmaloc SR Tablet (Sustained Release) contains Theophylline. Asmaloc SR uses:

This is indicated for the symptomatic treatment of reversible bronchoconstriction associated with bronchial asthma, chronic obstructive pulmonary emphysema, chronic bronchitis and related bronchospastic disorders.

Asmaloc SR Tablet (Sustained Release) Doses

Asmaloc SR Tablet (Sustained Release) contains Theophylline 400 mg. Asmaloc SR doses:

Dosages are adjusted to maintain serum theophylline concentrations that provide optimal relief of symptoms with minimal side effects. Most of the controlled release preparations may be administered every 12 hours in adults while administration every 8 hours may be necessary in some children with markedly rapid hepatic metabolism of theophylline. The recommended dosages for achieving serum theophylline concentrations within the accepted therapeutic range is as follow: 

  • 1-6 months: 10 mg/Kg/day
  • 6 months-1 year: 15 mg/Kg/day
  • 1-9 years: 24 mg/Kg/day
  • 10-16 years: 18 mg/Kg/day
  • Adults: 10-15 mg/Kg/day


Side Effects

The following side effects have been observed:

Gastrointestinal: Nausea, vomiting, epigastric pain and diarrhoea.

Central nervous system: Headache, irritability, restlessness, insomnia, muscles twitching.

Cardiovascular: Palpitation, tachycardia, hypotension. circulatory failure.

Respiratory: Tachypnoea.Renal: Potentiation of diuresis.

Others: Alopecia, hyperglycemia, rash etc.


Asmaloc SR Tablet (Sustained Release) is a bronchodilator, structurally classified as a Methylxanthine. Asmaloc SR Tablet (Sustained Release) has two distinct actions in the airways of patients with reversible obstruction; smooth muscle relaxation and suppression of the response of the airways to stimuli. Asmaloc SR Tablet (Sustained Release) also increases the force of contraction of diaphragmatic muscles. The half-life of Asmaloc SR Tablet (Sustained Release) is influenced by a number of known variables. In adult nonsmokers with uncomplicated asthma the half-life ranges from 3 to 9 hours

Asmaloc SR Precaution

Careful consideration is needed for various interacting drugs and physiologic conditions that can alter Asmaloc SR Tablet (Sustained Release) clearance. Dosage adjustment is required prior to initiation of Asmaloc SR Tablet (Sustained Release) therapy, prior to increases in Asmaloc SR Tablet (Sustained Release) dose, and during follow up. The dose of Asmaloc SR Tablet (Sustained Release) selected for initiation of therapy should be low and, if tolerated, increased slowly over a period of time.


Allopurinol, cimetidine, norfloxacin, ciprofloxacin, erythromycin, oral contraceptives and propranolol increase serum theophylline levels. Phenytoin, methotrexate and rifampicin lead to decreased serum theophylline levels

Pregnancy Lactation use

Pregnancy: It is not known whether Asmaloc SR Tablet (Sustained Release) can cause foetal harm when administered to pregnant woman.Xanthines should be given to a pregnant woman only if clearly needed.

Nursing mother: Asmaloc SR Tablet (Sustained Release) is excreted into breast milk and may cause irritability or other signs of mild toxicity in nursing human infants. Serious adverse effects in the infant are unlikely unless the mother has toxic serum Asmaloc SR Tablet (Sustained Release) concentrations.


Hypersensitivity to xanthine derivatives. It is also contraindicated in patients with active peptic ulcer disease and in individuals with underlying seizure disorders (unless receiving appropriate anti-convulsing medication).

Asmaloc SR Tablet (Sustained Release) should not be administered concurrently with other xanthine. Use with caution in patients with hypoxemia, hypertension, or those with history of peptic ulcer. Do not attempt to maintain any dose that is not tolerated.

Special Warning


Acute Overdose

Symptoms may include nausea, vomiting, gastrointestinal irritation, cramps, convulsions, tachycardia & hypotension. The stomach contents should be emptied & supportive measures employed to maintain circulation, respiration & fluid & electrolyte balance. Electrocardiographic monitoring should be carried out & in severe poisoning charcoal haemoperfusion should be used.

Interaction with other Medicine


Storage Condition

Store in a cool and dry place, protect from light and moisture. Keep out of the reach of children

Asmaloc SR Tablet (Sustained Release) price in Bangladesh 4.17