Artoflex

Artoflex Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Artoflex is a brand name. Its generic name is Dexibuprofen.

Introduction

Artoflex is a non-steroidal anti-inflammatory drug (NSAID), which is used for relief of pain and inflammation. It belongs to the class of drugs called COX-2 inhibitors, which reduces pain and inflammation. Artoflex was approved by the US FDA in July 2017.

Uses

Artoflex is used to treat moderate to severe pain, inflammation and stiffness associated with arthritis and musculoskeletal conditions such as bursitis, tendinitis, and joint pain. It is also used to treat headaches, menstrual cramps, and other common pains.

Mechanism of Action

Artoflex works by blocking the action of cyclooxygenase (COX), an enzyme involved in the production of substances called prostaglandins. Prostaglandins are responsible for causing inflammation, pain, and swelling. By blocking the enzyme, Artoflex blocks the production of these prostaglandins, thereby reducing the pain and inflammation caused by the affected condition.

How long does it take to work?

The effects of Artoflex typically begin to take effect within 30 minutes to an hour after taking the drug. The drug may take up to 8 hours to show its full effects of relieving pain and inflammation.

Absorption

Artoflex is rapidly and almost completely absorbed from the gastrointestinal tract. The peak serum levels of the drug occur approximately 1-2 hours after oral administration.

Route of Elimination

Artoflex is metabolized in the liver and excreted in the urine and feces.

Dosage

The typical recommended dosage of Artoflex is 400 to 800 mg per day, taken orally in divided doses (usually, twice a day). The dose may be increased or decreased based on the patient’s response to the medication.

Administration

Artoflex is available in oral tablets and capsules, as well as in a liquid suspension. The tablets and capsules should be taken with a glass of water once or twice a day, as directed by the doctor. The liquid form of Artoflex should be taken with food or after meals.

Side Effect

Some of the common side effects of Artoflex include nausea, vomiting, abdominal pain, indigestion, headache, dizziness, and diarrhea. Serious side effects such as bloody or black, tarry stools, chest pain, difficulty breathing, and weakness in the arms and legs have also been reported.

Toxicity

High doses of Artoflex can lead to severe liver or kidney damage and even cause death. Regular monitoring of liver function tests is recommended in patients taking Artoflex. If any signs of liver or kidney damage appear, the dose of Artoflex should be reduced or stopped immediately.

Precautions

Artoflex should be used with caution in patients with a history of asthma, stomach or intestinal ulcers, kidney or liver disease, bleeding disorders, or any other medical condition. It should not be used by pregnant women or those who are breastfeeding. People taking blood thinning medications should also avoid taking Artoflex.

Interactions

Artoflex may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Artoflex.

Disease Interaction

Artoflex may interact with certain diseases, such as asthma, gastrointestinal ulcers, kidney or liver disease, or any other medical condition. People with these diseases should use Artoflex with caution and monitor their condition closely.

Drug Interactions

Artoflex may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Artoflex.

Food Interactions

Artoflex may interact with certain foods, such as dairy products, alcohol, and spicy foods. It is best to avoid these foods while taking Artoflex to minimize any potential interactions.

Pregnancy Use

Artoflex should be used with caution during pregnancy and should only be used if the potential benefits outweigh the risks to the baby. It is not recommended for pregnant women due to the potential for fetal damage or harm.

Lactation Use

Artoflex should not be used while breastfeeding as it can pass into breast milk.

Acute Overdose

An overdose of Artoflex can cause serious side effects, such as nausea, vomiting, abdominal pain, drowsiness, confusion, dizziness, fainting, respiratory depression, and death. If an overdose is suspected, seek medical attention immediately.

Contraindication

Artoflex should not be used in patients with a known hypersensitivity to ibuprofen or other NSAIDs. Patients with a history of asthma, stomach or intestinal ulcers, bleeding disorders, kidney or liver disease, or any other medical condition should also avoid using Artoflex.

Use Directions

Artoflex should be taken exactly as prescribed by the doctor. The tablets and capsules should be taken with a full glass of water once or twice a day, as directed. The liquid form of Artoflex should be taken with food or after meals.

Storage Condition

Artoflex should be stored at room temperature away from direct light and moisture. Keep it away from pets, children, and any other medicines.

Volume of Distribution

Artoflex has a volume of distribution of approximately 0.5 l/kg.

Half Life

The half-life of Artoflex is approximately 2-3 hours.

Clearance

The clearance rate of Artoflex is approximately 0.7 ml/min/kg.

Here you find in details version of Artoflex

Some Frequently Asked Questions About Artoflex

What is Artoflex?

Artoflex is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce symptoms of inflammation and pain.

What are the uses of Artoflex?

Artoflex is used to treat pain, inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and juvenile arthritis.

How should I take Artoflex?

Artoflex should be taken exactly as prescribed by your doctor. The usual adult dose is 200 to 400 mg every 4 to 6 hours.

Is Artoflex safe?

Yes, Artoflex is generally safe when taken as prescribed. However, like any medicine, there may be side effects or interactions with other medications.

Is Artoflex habit-forming?

No, Artoflex is not habit-forming and does not have any known abuse potential.

Are there any food or drink interactions with Artoflex?

Yes, Artoflex may interact with alcohol, caffeine, and certain foods. Therefore, it is important to check with your doctor or pharmacist before taking Artoflex.

What are the possible side effects of Artoflex?

Common side effects of Artoflex include abdominal pain, diarrhea, nausea, and headache. More serious side effects can occur, so it is important to talk to your doctor if you experience any unusual symptoms while taking Artoflex.

Does Artoflex have any interactions with other medications?

Yes, Artoflex may interact with some other medications, including aspirin, warfarin, and other NSAIDs. It is important to consult your doctor or pharmacist before taking any medications in combination with Artoflex.

What is the maximum daily dose of Artoflex?

The maximum daily dose of Artoflex is 800 mg per day for adults. For children, the maximum daily dose is determined based on age and weight.

What is the difference between Artoflex and ibuprofen?

Artoflex is a newer, long-acting version of ibuprofen, with a longer duration of action in the body. Artoflex is usually taken less frequently than ibuprofen, and is only available as a prescription medication.

Can pregnant or breastfeeding women take Artoflex?

It is not recommended for pregnant or breastfeeding women to take Artoflex. Women who are pregnant or breastfeeding should consult their doctor before taking any medication, including Artoflex.

Is Artoflex the same as aspirin or acetaminophen?

No, Artoflex is not the same as aspirin or acetaminophen. Artoflex is an NSAID, while aspirin and acetaminophen are not NSAIDs.

How does Artoflex work?

Artoflex works by blocking the production of certain chemicals in the body that cause inflammation and pain. This provides relief from the pain and inflammation associated with arthritis.

Can I take Artoflex with other medications?

It is not recommended to take Artoflex with certain other medications, such as aspirin, warfarin, or other NSAIDs. Consult your doctor or pharmacist before taking Artoflex with any other medication.

How long does it take for Artoflex to work?

It can take up to an hour for Artoflex to start relieving pain and inflammation. The effects of Artoflex can last for up to six hours.

In what form is Artoflex available?

Artoflex is available as a tablet, capsule, suspension, and injection. It is also available as an oral liquid for children.

How long does Artoflex take to leave the body?

The half-life of Artoflex is about 8 hours, so it takes an average of 24 to 36 hours for the drug to be completely eliminated from the body.

Can I buy Artoflex over-the-counter?

No, Artoflex is not available over the counter. It is only available by prescription from a doctor.

Is Artoflex addictive?

No, Artoflex is not an addictive drug and has no known abuse potential.

What happens if I take too much Artoflex?

Taking too much Artoflex can cause serious side effects like nausea, vomiting, stomach pain, drowsiness, headache, dizziness, or blurred vision. In some cases, it can even cause stomach or intestinal bleeding. If you take too much Artoflex, you should seek immediate medical attention.

Can I take Artoflex if I have liver or kidney problems?

It is not recommended for people with liver or kidney problems to take Artoflex. People with liver or kidney problems should consult their doctor before taking any medication.

Can Artoflex cause drowsiness?

Yes, Artoflex can cause drowsiness or dizziness in some people. It is important to check with your doctor before taking Artoflex if you are taking other medications that can cause drowsiness.

Does Artoflex interact with other substances?

Yes, Artoflex can interact with certain substances, such as alcohol, caffeine, and certain foods. It is important to discuss all medications and substances with your doctor before taking Artoflex.

How long can I take Artoflex safely?

It is not recommended to take Artoflex for longer than 10 days without consulting a doctor. Taking Artoflex for an extended period of time can increase the risk of serious side effects.

What should I do if I miss a dose of Artoflex?

If you miss a dose of Artoflex, take it as soon as you remember. Do not take two doses at once. If you take too much Artoflex, seek immediate medical attention.

Is Artoflex covered by insurance?

It depends. Most health insurance plans cover some or all of the cost of Artoflex. Check with your insurance provider for details on your coverage.

Are there any long-term side effects of taking Artoflex?

Long-term use of Artoflex can increase the risk of stomach or intestinal bleeding, heart attack, stroke, and kidney damage. If you are taking Artoflex for a prolonged period of time, it is important to talk to your doctor about the risks.

Does Artoflex affect blood pressure?

Yes, Artoflex can cause an increase in blood pressure. People with high blood pressure should consult their doctor before taking any medication, including Artoflex.

Can children take Artoflex?

Artoflex is approved for use in children as young as 2 years old. The dose and form of Artoflex used in children will be determined by the doctor and should be taken according to the doctor’s instructions.

Is Artoflex a steroid?

No, Artoflex is not a steroid. It is a nonsteroidal anti-inflammatory drug (NSAID).

What will happen if I stop taking Artoflex suddenly?

It is not recommended to stop taking Artoflex suddenly. If you need to stop taking Artoflex, talk to your doctor about how to do so safely.

Can I take Artoflex with food?

Yes, Artoflex can be taken with or without food. However, it is important to follow your doctor’s instructions and not take more than the recommended dose.

What other medications can I take with Artoflex?

It is important to talk to your doctor or pharmacist before taking any medications in combination with Artoflex, as some medications can interact with it. Some medications that are safe to take with Artoflex include acetaminophen, ibuprofen, and topical creams.

Can Artoflex be used for headaches?

Yes, Artoflex can be used for the temporary relief of headaches. If you experience frequent or severe headaches, it is important to talk to your doctor.

Does Artoflex help with swelling?

Yes, Artoflex is commonly used to reduce pain and swelling associated with conditions like osteoarthritis and rheumatoid arthritis.

Can I take Artoflex if I have a history of stomach ulcers?

It is not recommended for people with a history of stomach ulcers to take Artoflex. People with a history of stomach ulcers should talk to their doctor before taking any medication.

Can Artoflex help with menstrual cramps?

Yes, Artoflex can help to relieve pain associated with menstrual cramps. If menstrual cramps are severe or frequent, it is important to talk to a doctor.

Is Artoflex suitable for people with allergies?

Yes, Artoflex is suitable for people with allergies. People with allergies should check with their doctor before taking any medication, including Artoflex.

Can I take Artoflex with an antacid?

Yes, you can take Artoflex with an antacid. However, it is important to take antacids at least two hours before or after taking Artoflex to ensure maximum effectiveness.