Artiflex

Artiflex Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Artiflex is a brand name. Its generic name is Celecoxib.

Introduction

Artiflex, also known as Celebrex, is an NSAID medication used to treat various conditions of inflammation and pain. Commonly used to treat arthritis, Artiflex works by inhibiting the enzyme COX-2, reducing inflammation and decreasing pain.

Uses

Artiflex is commonly used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, menstrual pain, and pain caused by inflammation (such as that associated with injuries). It is also used to reduce the number of colorectal polyps in people with familial adenomatous polyposis.

Mechanism of Action

Artiflex works by inhibiting the COX-2 enzyme, which is responsible for the production of several pro-inflammatory mediators in the body. By blocking the action of this enzyme, the amount of these mediators is reduced, leading to decreased inflammation and pain.

How Long Does It Take to Work?

The effects of Artiflex usually begin within 3-4 days of taking the medication. It may take up to two weeks to feel the full effects of the medication.

Absorption

Artiflex is rapidly and extensively absorbed from the gastrointestinal tract after oral administration.

Route of Elimination

Artiflex is eliminated in the feces and urine. About 80% of an administered dose is recovered in feces as unchanged drug, metabolites, and biliary excretion products. About 30% of the drug is eliminated unchanged in the urine.

Dosage

The recommended adult dose for Artiflex is 200-400 mg taken twice daily. The maximum daily dose is 800 mg. Dosage should be adjusted in patients with impaired kidney function.

Administration

Artiflex should be taken with a full glass of water and should be taken on an empty stomach.

Side Effects

Common side effects of Artiflex include nausea, stomach pain, diarrhea, dizziness, constipation, gas, heartburn, drowsiness, headache, and rash. Some serious side effects may include swelling of the face, hands, feet, ankles, stomach pains, chest pain, and difficulty breathing.

Toxicity

Artiflex is generally well tolerated. However, Artiflex can cause serious side effects if taken in high doses and when used for long periods of time. The risk of serious side effects increases with the duration of treatment.

Precautions

Patients taking Artiflex should be aware of the potential risk for stomach ulcers and bleeding. Patients should also be aware of the risk of hypersensitivity reactions and kidney impairment associated with this medication.

Interaction

Artiflex can interact with other medications, including inhibitors of cytochrome P-450 isoenzymes, antibiotics, antifungals, antihypertensives, anticonvulsants, and some corticosteroids. Before using Artiflex, consult your doctor or pharmacist.

Disease Interaction

Patients with heart failure, high blood pressure, blood clotting disorders, or an allergy to NSAIDs should not take Artiflex. Patients with a pre-existing bleeding disorder, bleeding ulcer, or liver disease should use Artiflex with caution.

Drug Interactions

Artiflex may interact with a number of drugs, including warfarin, lithium, methotrexate, ACE inhibitors, and corticosteroids. Consult your doctor or pharmacist for a complete list of drug interactions.

Food Interactions

Alcohol should be avoided while taking Artiflex. Other foods high in fat may increase the rate of absorption of the medication.

Pregnancy Use

Artiflex is contraindicated in pregnant women. Other NSAIDs should be considered in pregnant women to avoid risk.

Lactation Use

Artiflex is contraindicated in breastfeeding women. Other NSAIDs should be considered in breastfeeding women to avoid risk.

Acute Overdose

In case of acute overdose, seek medical attention immediately. Symptoms may include confusion, vomiting, rash, stomach pain, and breathing difficulty.

Contraindication

Artiflex is contraindicated in pregnant women and breastfeeding women. Artiflex is also contraindicated in patients with a history of hypersensitivity reaction to Artiflex or any other NSAID.

Use Direction

Artiflex should be taken as directed by your health care provider. It should be taken with a full glass of water, and should be taken on an empty stomach. Do not exceed the recommended dosage.

Storage Condition

Artiflex should be stored at room temperature away from direct sunlight and heat. Keep out of reach of children.

Volume of Distribution

The average volume of distribution for Artiflex is approximately 17 L/kg.

Half Life

The average half-life of Artiflex is approximately 11 hours.

Clearance

The clearance for Artiflex is approximately 0.4 L/hr/kg.

Here you find in details version of Artiflex

Some Frequently Asked Questions About Artiflex

What is Artiflex?

Artiflex is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, inflammation, and stiffness caused by arthritis and some other conditions. It is sold under the brand names Celebrex and Celebra.

How does Artiflex work?

Artiflex is an anti-inflammatory drug that works by inhibiting the production of prostaglandins, substances that cause inflammation. This reduction in prostaglandins helps reduce pain and inflammation in patients with arthritis and other conditions.

What is the difference between Artiflex and other NSAIDs?

Artiflex is a newer generation of NSAIDs that are less likely to cause stomach irritation and bleeding. It is also less likely to cause kidney damage than traditional NSAIDs. It is commonly used for the treatment of arthritis and other painful conditions.

What are the side effects of Artiflex?

Common side effects of Artiflex include stomach upset, nausea, diarrhea, headache, and dizziness. Less common but more serious side effects include liver and kidney damage, increased risk of bleeding or stroke, and allergic reactions.

Is Artiflex safe to use long-term?

Artiflex is generally considered safe to use long-term, however it can increase risk of certain side effects such as stomach irritation and an increased risk of stroke or bleeding. Talk to your doctor to make sure Artiflex is right for you.

Can Artiflex be crushed or split in half?

No, Artiflex should not be crushed or split in half. Taking the whole capsule at once is the only safe way to take this medication.

What should be avoided while taking Artiflex?

Alcohol should be avoided while taking Artiflex, as it can increase the risk of stomach bleeding. You should also avoid using other medications including NSAIDs and steroids without talking to your doctor first, as they can increase the risk of side effects.

Is Artiflex safe to use during pregnancy and breastfeeding?

No, Artiflex should not be used during pregnancy or breastfeeding. If you are pregnant or think you might be pregnant, talk to your doctor before taking celecoxib.

Can Artiflex interact with other medications?

Yes, Artiflex can interact with other medications including NSAIDs, steroids, blood thinners, and some antibiotics. Talk to your doctor or pharmacist before starting or changing medications to make sure Artiflex is right for you.

How do you take Artiflex?

Artiflex should be taken exactly as your doctor or healthcare provider has prescribed. Do not take more or less than what is recommended. The usual recommended dose is 200 mg once or twice daily. It should be taken with food to reduce stomach irritation.

What should I do if I miss a dose of Artiflex?

If you miss a dose of Artiflex, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time.

How long does it take for Artiflex to start working?

It can take up to a few weeks for Artiflex to start working. If your symptoms do not improve after 4-6 weeks, talk to your doctor, as the dose may need to be adjusted.

Is Artiflex habit forming?

No, Artiflex is not habit forming. However, it is important to take the medication as prescribed and not to stop taking it without talking to your doctor first.

Is Artiflex safe to use in children?

Artiflex is not approved for use in children. Talk to your doctor before giving your child Artiflex.

Can Artiflex cause weight gain?

No, Artiflex does not typically cause weight gain, however some patients taking this medication may experience appetite changes. Talk to your doctor if you experience significant weight gain while taking Artiflex.

Should I take Artiflex with food?

Yes, Artiflex should be taken with food to reduce stomach irritation. Eating a full meal—including protein, vegetables, and some fat—will help protect your stomach.

Is Artiflex addictive?

No, Artiflex is not an addictive medication. However, it is important to take it as prescribed and not to stop taking it without talking to your doctor first.

Can Artiflex cause liver damage?

Yes, there is a risk of liver damage with long-term use of Artiflex. Your doctor may order regular blood tests to monitor your liver function if you take this medication for an extended period of time.

Can Artiflex be used for pain relief?

Yes, Artiflex is often used to treat pain and inflammation associated with arthritis and other conditions. Talk to your doctor to make sure Artiflex is right for you.

Should Artiflex be taken with other medications?

Artiflex can interact with many other medications. Talk to your doctor or pharmacist before starting or changing medications to make sure Artiflex is right for you.

Does Artiflex interact with birth control?

Yes, there is a potential for Artiflex to interact with birth control pills, leading to an increased risk of side effects. Talk to your doctor about safer alternatives for contraception if you take this medication.

Can Artiflex cause stomach pain?

Yes, some patients taking Artiflex may experience stomach pain. Taking the medication with food and eating a full meal—including protein, vegetables, and some fat—will help protect your stomach.

Can Artiflex cause drowsiness?

Yes, drowsiness is a possible side effect of Artiflex. Talk to your doctor if you experience excessive drowsiness while taking this medication.

Can Artiflex cause erectile dysfunction?

Yes, erectile dysfunction is a possible side effect of Artiflex. Talk to your doctor immediately if you experience any changes in your sexual function while taking this medication.

Can I take Artiflex and ibuprofen together?

No, taking both Artiflex and ibuprofen at the same time can increase your risk of stomach irritation and bleeding. Make sure to tell your doctor if you are already taking any other medications.

Should I take Artiflex with food or on an empty stomach?

Artiflex should be taken with food to reduce stomach irritation. Eating a full meal—including protein, vegetables, and some fat—will help protect your stomach.

Does Artiflex cause hair loss?

No, hair loss is not a common side effect of Artiflex. Talk to your doctor right away if you experience any changes in your hair while taking this medication.

Can Artiflex cause an allergic reaction?

Yes, allergic reactions to Artiflex are possible. Symptoms of an allergic reaction can include rash, itching, difficulty breathing, and swelling. Contact your doctor immediately if you experience any of these symptoms while taking this medication.

Can Artiflex cause constipation?

Yes, constipation is a possible side effect of Artiflex. If you experience constipation while taking this medication, talk to your doctor about ways to manage it.

Can Artiflex be used to treat fever?

No, Artiflex is not typically used to treat fever. Talk to your doctor about other options for treating fever.

Is Artiflex a blood thinner?

No, Artiflex is not a blood thinner. However, it can increase your risk of bleeding when taken with other blood thinning medications. Talk to your doctor before taking Artiflex with other medications.

Can Artiflex cause nausea?

Yes, nausea is a possible side effect of Artiflex. Talk to your doctor if you experience nausea while taking this medication.

Can Artiflex cause dehydration?

Yes, dehydration is a possible side effect of Artiflex. Make sure to drink plenty of fluids while taking this medication, especially if you are experiencing other symptoms such as nausea, vomiting, and diarrhea.

Can Artiflex cause stomach upset?

Yes, stomach upset is a possible side effect of Artiflex. Taking the medication with food and eating a full meal—including protein, vegetables, and some fat—will help protect your stomach.

What is the maximum daily dose of Artiflex?

The maximum recommended daily dose of Artiflex is 400 mg. Taking more than this can increase your risk of side effects. Talk to your doctor if you are prescribed a higher dose.

How long can I take Artiflex?

The maximum recommended duration of use of Artiflex is six months. Talk to your doctor if you need to take this medication for longer than this, as it can increase your risk of side effects.

Does Artiflex cause dizziness?

Yes, dizziness is a common side effect of Artiflex. If you experience dizziness while taking this medication, talk to your doctor about ways to manage it.

Should I take Artiflex with food or milk?

Artiflex should be taken with food to reduce stomach irritation. Eating a full meal—including protein, vegetables, and some fat—will help protect your stomach.

Does Artiflex reduce inflammation?

Yes, Artiflex is an anti-inflammatory drug that helps reduce inflammation by inhibiting the production of prostaglandins. This can reduce pain and inflammation in patients with arthritis and other conditions.

Does Artiflex cause weight gain?

No, weight gain is not typically caused by Artiflex. However, some patients taking this medication may experience appetite changes. Talk to your doctor if you experience significant weight gain while taking Artiflex.

Can Artiflex cause fatigue?

Yes, fatigue is a possible side effect of Artiflex. Talk to your doctor if you experience fatigue while taking this medication.

Can Artiflex cause heartburn?

Yes, heartburn is a possible side effect of Artiflex. Taking the medication with food and eating a full meal—including protein, vegetables, and some fat—will help protect your stomach.

Do I need to have regular blood tests while taking Artiflex?

Your doctor may order regular blood tests to monitor your liver function if you take this medication for an extended period of time. Talk to your doctor about any other tests you may need while using Artiflex.